Results 41 to 50 of about 226,651 (317)
Clinical Infectious Diseases, 2020 BACKGROUND Predictors of latent tuberculosis infection (LTBI) among close contacts of persons with infectious tuberculosis (TB) are incompletely understood, particularly the number of exposure hours.
M. Reichler +6 more
semanticscholar +1 more source
Tuberculosis and COVID-19 Dually Affect Human Th17 Cell Immune Response
Biomedicines, 2023 COVID-19 infection not only profoundly impacts the detection of tuberculosis infection (Tbc) but also affects modality in tuberculosis patient immune response.
Anna Starshinova +5 more
doaj +1 more source
Diagnosis of childhood tuberculosis and host RNA expression in Africa [PDF]
, 2014 Improved diagnostic tests for tuberculosis in children are needed. We hypothesized that transcriptional signatures of host blood could be used to distinguish tuberculosis from other diseases in African children who either were or were not infected with ...
Amelia C. Crampin +26 more
core +5 more sources
The knowns and unknowns of latent Mycobacterium tuberculosis infection.
Journal of Clinical Investigation, 2021 Humans have been infected with Mycobacterium tuberculosis (Mtb) for thousands of years. While tuberculosis (TB), one of the deadliest infectious diseases, is caused by uncontrolled Mtb infection, over 90% of presumed infected individuals remain ...
W. Boom, U. Schaible, J. Achkar
semanticscholar +1 more source
PLoS ONE, 2021 One principle of tuberculosis control is to prevent the development of tuberculosis disease by treating individuals with latent tuberculosis infection.
Henok G Woldu +7 more
doaj +1 more source
Journal of Clinical Microbiology, 2020 Identification of biomarkers for latent Mycobacterium tuberculosis infection and risk of progression to tuberculosis (TB) disease are needed to better identify individuals to target for preventive therapy, predict disease risk, and potentially predict ...
Carolina Mehaffy +8 more
semanticscholar +1 more source
Latent Tuberculosis Infection [PDF]
European Respiratory & Pulmonary Diseases, 2018 Tuberculosis (TB) is a major global public health problem and is the leading cause of death linked to a single pathogen, ranking above human immunodeficiency virus (HIV).1 Clinically, TB has been categorised as active disease (patients who are generally symptomatic and may be infectious if pulmonary involvement is present) and latent infection ...
openaire +1 more source
Spreading of Persistent Infections in Heterogeneous Populations [PDF]
, 2010 Up to now, the effects of having heterogeneous networks of contacts have been studied mostly for diseases which are not persistent in time, i.e., for diseases where the infectious period can be considered very small compared to the lifetime of an ...
D. Bleed +9 more
core +2 more sources
Analysis of Mycobacterium tuberculosis-specific CD8 T-cells in patients with active tuberculosis and in individuals with latent infection. [PDF]
PLoS ONE, 2009 CD8 T-cells contribute to control of Mycobacterium tuberculosis infection, but little is known about the quality of the CD8 T-cell response in subjects with latent infection and in patients with active tuberculosis disease.
Nadia Caccamo +14 more
doaj +1 more source
Outlook for tuberculosis elimination in California: An individual-based stochastic model. [PDF]
, 2019 RationaleAs part of the End TB Strategy, the World Health Organization calls for low-tuberculosis (TB) incidence settings to achieve pre-elimination (<10 cases per million) and elimination (<1 case per million) by 2035 and 2050, respectively. These
Barry, Pennan M +10 more
core +3 more sources