Results 61 to 70 of about 53,392 (269)

The role of the Interferon gamma release assay in assessing recent tuberculosis transmission in a hospital incident [PDF]

, 2011
In 2007, an extensive contact screening investigation into onward transmission of tuberculosis was instigated at a hospital in Northern Ireland following diagnosis of pulmonary multi-drug resistant TB in a healthcare worker.
Abubakar, Ibrahim, Nikolayevskyy, V, Elizabeth Davies, Abubakar, I, Flanagan, P, Paul Kelly, Davies Elizabeth, Abubakar Ibrahim, O'Connor, K, Vladislav Nikolayevskyy, Davies, E, Nikolayevskyy Vladislav, Bradshaw Louise, Flanagan, Peter, Davies, Elizabeth, Devine, M, Devine, Michael, Kevin O'Connor, Peter Flanagan, Drobniewski, F, Kelly Paul, Nikolayevskyy, Vladislav, Drobniewski, Francis, Ibrahim Abubakar, O'Connor Kevin, O'Connor, Kevin, Louise Bradshaw, Francis Drobniewski, Bradshaw, L, Bradshaw, Louise, Kelly, Paul, Michael Devine, Flanagan Peter, Devine Michael, Kelly, P, Drobniewski Francis   +35 more
core   +1 more source

Incidence and risk factors for tuberculosis in people living with HIV: cohort from HIV referral health centers in Recife, Brazil. [PDF]

PLoS ONE, 2013
OBJECTIVE: To identify the incidence of and risk factors for tuberculosis in people living with HIV (PLHIV). DESIGN: Observational, prospective cohort study. METHODS: A total of 2069 HIV-infected patients was observed between July 2007 and December 2010.
Joanna d'Arc Lyra Batista, Maria de Fátima Pessoa Militão de Albuquerque, Magda Maruza, Ricardo Arraes de Alencar Ximenes, Marcela Lopes Santos, Ulisses Ramos Montarroyos, Demócrito de Barros Miranda-Filho, Heloisa Ramos Lacerda, Laura Cunha Rodrigues   +8 more
doaj   +1 more source

Treatment of Latent Tuberculosis Infection in Children [PDF]

Journal of the Pediatric Infectious Diseases Society, 2013
Treatment of latent tuberculosis infection (LTBI) is an effective way of preventing future cases of tuberculosis disease. We review pediatric and adult studies of LTBI treatment (isoniazid and rifampin monotherapy, isoniazid plus rifampin, isoniazid plus rifapentine, and rifampin plus pyrazinamide).
Andrea T, Cruz, Amina, Ahmed, Anna M, Mandalakas, Jeffrey R, Starke   +3 more
openaire   +2 more sources

Latent tuberculosis infection and kidney transplantation [PDF]

Brazilian Journal of Nephrology, 2021
The incidence rate of tuberculosis (TB) in kidney transplant (KT) recipients is higher than that in the normal population, and it is associated with unfavorable outcomes including graft loss and mortality1. Screening for latent TB (LTBI) in KT candidates can be accomplished by a thorough clinical history and physical examination, chest radiography, and
openaire   +4 more sources

The evolution of covert, silent infection as a parasite strategy [PDF]

, 2009
Many parasites and pathogens cause silent/covert infections in addition to the more obvious infectious disease-causing pathology. Here, we consider how assumptions concerning superinfection, protection and seasonal host birth and transmission rates ...
White, Andrew, Boots, Mike, Pedersen, Amy B., Sorrell, Ian, Hails, Rosemary S., White, A, Sorrell, I, Pedersen, AB, Boots, M, White, Andrew; id_orcid, Hails, RS   +10 more
core   +1 more source

Prevalence of latent Mycobacterium tuberculosis infection among professionals of the primary healthcare network

Revista Brasileira em Promoção da Saúde, 2014
Objective: To estimate the prevalence of latent M. tuberculosis infection and identify characteristics related to latent infection among workers of the primary healthcare network.Methods: Cross-sectional, observational and descriptive study, conducted in
Tássia Silvana Borges, Eduardo Chaida Sonda, Alexandre Daronco, Fabiana Battisti, Marcos Moura Baptista Dos Santos, Andréia Rosane Moura Valim, Mariana Valença, Lia Gonçalves Possuelo   +7 more
doaj   +1 more source

Substrate Characterization of Mycobacterial Kinase PknG Revealing PknG‐KARS‐MAPK Phosphorylation Signaling Axis in Host

iMetaMed, EarlyView.
This study employed multi‐omics approaches to investigate the regulatory mechanism of Mycobacterium PknG on host cell processes. We found that host lysine‐tRNA ligase (KARS) is a potential substrate of PknG; and PknG can regulate the immune response by catalyzing the phosphorylation of KARS at T592 and T595 sites, affecting the phosphorylation level in
Nana Tian, Shuyu Xie, Yanqing Tang, Junjie Liang, Wenhan Zhu, Tianqi Liu, Yewen Sun, Yang Yang, Luoxi Zhang, Danfeng Wang, Chuyao Lin, Jinyu Jia, Minjia Tan, Jun‐Yu Xu   +13 more
wiley   +1 more source

Maintenance of Sensitivity of the T-SPOT.TB Assay after Overnight Storage of Blood Samples, Dar es Salaam, Tanzania. [PDF]

, 2012
Background. T-SPOT.TB is an interferon gamma release assay for detecting Mycobacterium tuberculosis infection. The requirement to process within 8 hours is constraining, deters use, and leads to invalid results. Addition of T Cell Xtend reagent may allow
Matee, M., Mtei, L., Adams, Lisa V, Ferguson, K., Adams, L.V., Matee, Mecky, Talbot, Elizabeth A, Mtei, Lillian, Maro, Isaac, von Reyn, C.F., Ferguson, Katherine, Maro, I., von Reyn, C Fordham, Talbot, E.A.   +13 more
core   +1 more source

Multi‐omics biomarkers for intestinal infection and inflammation in inflammatory bowel disease: Current evidence, translational challenges, and diagnostic opportunities

Interdisciplinary Medicine, EarlyView.
Prospective multi‐site cohorts, multi‐omics profiling, and computational analysis may help identify biomarker patterns across clinical settings in IBD and superimposed infections. With further mechanistic and clinical validation, these signals could support the development of practical multi‐analyte tools for more precise diagnosis and management ...
Ziyu Yang, Jiayi Yao, Xinxian Zhao, Yan Xu, Yifan Chen, Tianchi Chen, Ying Jian, Min Li   +7 more
wiley   +1 more source

Diagnostic Performance of Comprehensive Point‐of‐Care Ultrasound for Pediatric Tuberculosis in Spain: A Prospective Observational Study

Journal of Clinical Ultrasound, EarlyView.
In children with presumptive tuberculosis, comprehensive point‐of‐care (cPOCUS) identified key thoracic abnormalities with high specificity and excellent inter‐reader reliability. Although diagnostic sensitivity was modest and examinations often incomplete, cPOCUS shows promise as a complementary, radiation‐free imaging tool.
Isabelle Munyangaju, Antoni Noguera‐Julian, Aleix Soler‐Garcia, Antoni Soriano‐Arandes, José Miguel Escudero Fernández, Maria Espiau, Begoña Santiago Garcia, Alicia Hernanz‐Lobo, Ángel M. Lancharro Zapata, Enrique Ladera, Angela Manzanares, Daniel Blazquez, Elisa Aguirre Pascual, Isabelle Thierry‐Chef, Danilo Buonsenso, Xavier Serres‐Créixams, Quique Bassat, Elisa Lopez‐Varela   +17 more
wiley   +1 more source