Results 61 to 70 of about 2,138,623 (198)

Safety and immunogenicity of a new tuberculosis vaccine, MVA85A, in mycobacterium tuberculosis–infected individuals [PDF]

open access: yes, 2009
Copyright © 2009 by the American Thoracic Society.Rationale: An effective new tuberculosis (TB) vaccine regimen must be safe in individuals with latent TB infection (LTBI) and is a priority for global health care.
Beveridge, NER   +17 more
core   +1 more source

Utility of newer technologies for the diagnosis of active and latent tuberculosis [PDF]

open access: yes, 2010
Includes bibliographical references (leaves 91-109).Since the 1800s the tuberculin skin test (TST) has been the only available test for latent tuberculosis (LTBI). Recently, interferon-gamma release assays (IGRAs) have been developed which are based upon
Cashmore, Tamaryn Jane
core   +1 more source

Monitoring CD27 expression to evaluate Mycobacterium tuberculosis activity in HIV-1 infected individuals in vivo. [PDF]

open access: yes, 2011
The level of bacterial activity is only poorly defined during asymptomatic Mycobacterium tuberculosis (MTB) infection. The objective was to study the capacity of a new biomarker, the expression of the T cell maturation marker CD27 on MTB-specific CD4 T ...
Geldmacher Christof   +31 more
core   +2 more sources

Tuberculosis in antiretroviral treatment programs in lower income countries: availability and use of diagnostics and screening. [PDF]

open access: yes, 2013
In resource-constrained settings, tuberculosis (TB) is a common opportunistic infection and cause of death in HIV-infected persons. TB may be present at the start of antiretroviral therapy (ART), but it is often under-diagnosed. We describe approaches to
Samuel Ajayi   +110 more
core   +3 more sources

miRNA Signatures in Sera of Patients with Active Pulmonary Tuberculosis. [PDF]

open access: yes, 2013
Several studies showed that assessing levels of specific circulating microRNAs (miRNAs) is a non-invasive, rapid, and accurate method for diagnosing diseases or detecting alterations in physiological conditions.
Matteelli A.   +78 more
core   +1 more source

The role of the Interferon gamma release assay in assessing recent tuberculosis transmission in a hospital incident [PDF]

open access: yes, 2011
In 2007, an extensive contact screening investigation into onward transmission of tuberculosis was instigated at a hospital in Northern Ireland following diagnosis of pulmonary multi-drug resistant TB in a healthcare worker.
Abubakar, Ibrahim   +35 more
core   +2 more sources

The evolution of covert, silent infection as a parasite strategy [PDF]

open access: yes, 2009
Many parasites and pathogens cause silent/covert infections in addition to the more obvious infectious disease-causing pathology. Here, we consider how assumptions concerning superinfection, protection and seasonal host birth and transmission rates ...
White, Andrew   +10 more
core   +1 more source

The use of anti-tuberculosis therapy for latent TB infection [PDF]

open access: yes, 2010
Justin T Denholm1,2, Emma S McBryde1,21Victorian Infectious Diseases Service, Royal Melbourne Hospital, Melbourne, Victoria, Australia; 2Department of Medicine, (RMH/WH), University of Melbourne, Parkville, Victoria, AustraliaAbstract: Tuberculosis ...
Denholm, Justin T.   +6 more
core   +1 more source

Maintenance of Sensitivity of the T-SPOT.TB Assay after Overnight Storage of Blood Samples, Dar es Salaam, Tanzania. [PDF]

open access: yes, 2012
Background. T-SPOT.TB is an interferon gamma release assay for detecting Mycobacterium tuberculosis infection. The requirement to process within 8 hours is constraining, deters use, and leads to invalid results. Addition of T Cell Xtend reagent may allow
Matee, M.   +13 more
core   +1 more source

Pathogenesis, Immunology, and Diagnosis of Latent Mycobacterium tuberculosis Infection

open access: yesClinical and Developmental Immunology, 2011
Phagocytosis of tubercle bacilli by antigen-presenting cells in human lung alveoli initiates a complex infection process by Mycobacterium tuberculosis and a potentially protective immune response by the host. M.
Suhail Ahmad
doaj   +1 more source

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