Results 41 to 50 of about 46,620 (192)

Managing latent tuberculosis infection and tuberculosis in children

Pulmonology, 2018
Tuberculosis (TB) is a major cause of childhood morbidity and mortality worldwide. The aim of this review is to describe the management of the child with TB and latent tuberculosis infection (LTBI). To develop this article, a working group reviewed relevant epidemiological and other scientific studies and established practices in conducting LBTI and TB
I. Carvalho, D. Goletti, S. Manga, D.R. Silva, D. Manissero, G. Migliori   +5 more
openaire   +4 more sources

Treatment of Latent Tuberculosis Infection in Children [PDF]

Journal of the Pediatric Infectious Diseases Society, 2013
Treatment of latent tuberculosis infection (LTBI) is an effective way of preventing future cases of tuberculosis disease. We review pediatric and adult studies of LTBI treatment (isoniazid and rifampin monotherapy, isoniazid plus rifampin, isoniazid plus rifapentine, and rifampin plus pyrazinamide).
Andrea T, Cruz, Amina, Ahmed, Anna M, Mandalakas, Jeffrey R, Starke   +3 more
openaire   +2 more sources

Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications

British Journal of Clinical Pharmacology, EarlyView.
Dolutegravir underpins modern first‐ and second‐line HIV treatment regimens; however, interindividual variability in its disposition and tolerability presents challenges for optimal use. This scoping review mapped current evidence on the pharmacogenomics of dolutegravir, focusing on pharmacokinetics and pharmacodynamics, and methodological limitations ...
Ronald Kiguba, Mishael Ssesanga, Munir Pirmohamed   +2 more
wiley   +1 more source

Prevalence and Risk Factors of Latent Tuberculosis Infection (LTBI) at Madura Boarding School as a High-Risk Congregate Setting

Juxta: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Introduction: Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a highly contagious airborne disease. High-risk environments with frequent close interactions contribute to the spread of TB.
Muhammad Arif Ananto, Retno Asih Setyoningrum, Pudji Lestari   +2 more
doaj   +1 more source

Latent Tuberculosis Infection Care [PDF]

Clinical Infectious Diseases, 2022
Katherine M Gaskell, Timesh D Pillay, James Brown, Moerida Belton, Stephen O Mepham, David A J Moore, Marc Lipman   +6 more
openaire   +3 more sources

Incidence and risk factors for tuberculosis in people living with HIV: cohort from HIV referral health centers in Recife, Brazil. [PDF]

PLoS ONE, 2013
OBJECTIVE: To identify the incidence of and risk factors for tuberculosis in people living with HIV (PLHIV). DESIGN: Observational, prospective cohort study. METHODS: A total of 2069 HIV-infected patients was observed between July 2007 and December 2010.
Joanna d'Arc Lyra Batista, Maria de Fátima Pessoa Militão de Albuquerque, Magda Maruza, Ricardo Arraes de Alencar Ximenes, Marcela Lopes Santos, Ulisses Ramos Montarroyos, Demócrito de Barros Miranda-Filho, Heloisa Ramos Lacerda, Laura Cunha Rodrigues   +8 more
doaj   +1 more source

Latent Tuberculosis Infection [PDF]

European Respiratory & Pulmonary Diseases, 2018
Tuberculosis (TB) is a major global public health problem and is the leading cause of death linked to a single pathogen, ranking above human immunodeficiency virus (HIV). 1 Clinically, TB has been categorised as active disease (patients who are generally symptomatic and may be infectious if ...
openaire   +1 more source

Prevalence of latent Mycobacterium tuberculosis infection among professionals of the primary healthcare network

Revista Brasileira em Promoção da Saúde, 2014
Objective: To estimate the prevalence of latent M. tuberculosis infection and identify characteristics related to latent infection among workers of the primary healthcare network.Methods: Cross-sectional, observational and descriptive study, conducted in
Tássia Silvana Borges, Eduardo Chaida Sonda, Alexandre Daronco, Fabiana Battisti, Marcos Moura Baptista Dos Santos, Andréia Rosane Moura Valim, Mariana Valença, Lia Gonçalves Possuelo   +7 more
doaj   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Treatment of latent tuberculosis infection: An update [PDF]

Respirology, 2010
ABSTRACTIsoniazid (INH) has been the mainstay of treatment of latent tuberculosis infection for almost 50 years. The currently recommended preferred regimen is 9 months daily self‐administered INH (9H); this has efficacy of more than 90% if completed properly.
Philip, Lobue, Dick, Menzies
openaire   +2 more sources