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Sex‐specific brain reserve and progression from mild cognitive impairment to Alzheimer's disease dementia

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION Sex differences exist in Alzheimer's disease (AD) treatment response, but the role of sex in disease development and progression remains unclear. METHODS We performed multimodal analyses of AD biomarker–positive individuals with mild cognitive impairment (MCI) and AD from the Alzheimer's Disease Neuroimaging Initiative (ADNI; MCI ...
Xulin Liu, Sterre C. M. de Boer, Maria Carmela Tartaglia, for the Alzheimer's Disease Neuroimaging Initiative   +3 more
wiley   +1 more source

Whole-Brain Monosynaptic Inputs to and Axonal Projections From Posterior Insular Cortex GABAergic Neurons in Mice. [PDF]

CNS Neurosci Ther
Qi WQ, Zhang XY, Ma WX, Qu WM, Shi JQ, Huang ZL, Zhu YL.   +6 more
europepmc   +1 more source

The proto-cortical amygdala: a perspective on the functional and evolutionary relationship between the basolateral amygdala complex and neocortex in mammals. [PDF]

Brain Struct Funct
James FLJ, Ahamed SK, Yang C, Wilson R, Canales JJ, Caruso V, Johnson LR.   +6 more
europepmc   +1 more source

Anterior Cingulate Cortex Projections to the Amygdala in Primates: Topographic and Layer-Specific Organization Underlying Emotion and Mood Regulation. [PDF]

J Neurosci
Kimura K, Soga Y, Yoshino R, Zheng A, Nonomura S, Yan G, Tanabe S, Nakamura S, Ohara S, Inoue KI, Takada M, Tsutsui KI.   +11 more
europepmc   +1 more source

Differential effects of acute, chronic, and social defeat stress on microglial morphology in the basolateral and central amygdala, and the medial and lateral habenula. [PDF]

Brain Struct Funct
Nieto-Quero A, Munoz-Martin J, Infantes-López MI, Tabbai S, Arjona A, Zambrana-Infantes E, Chaves-Peña P, Blanca MJ, Pérez-Martín M, Pedraza C.   +9 more
europepmc   +1 more source

Amygdala pathology in amyotrophic lateral sclerosis and primary lateral sclerosis [PDF]

Journal of the Neurological Sciences, 2020
Temporal lobe studies in motor neuron disease overwhelmingly focus on white matter alterations and cortical grey matter atrophy. Reports on amygdala involvement are conflicting and the amygdala is typically evaluated as single structure despite consisting of several functionally and cytologically distinct nuclei.
Alice Vajda, Niall P. Pender, Siobhan Hutchinson   +2 more
exaly   +4 more sources

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Auditory fear conditioning facilitates neurotransmitter release at lateral amygdala to basal amygdala synapses

Biochemical and Biophysical Research Communications, 2021
The lateral amygdala (LA) is a main sensory input site from the cortical and thalamic regions. In turn, LA glutamatergic pyramidal neurons strongly project to the basal amygdala (BA). Although it is well known that auditory fear conditioning involves synaptic potentiation in the LA, it is not clear whether the LA-BA synaptic transmission is modified ...
Kyuhyun Choi, Kyungjoon Park, Soonje Lee, Jee Hyun Yi, Changsu Woo, Shin Jung Kang, Ki Soon Shin   +6 more
openaire   +2 more sources

Neuronal configurations in lateral and basolateral amygdala

Neuroscience, 1983
The lateral and basolateral nuclei of the rat amygdala have been studied with the rapid Golgi method. Both nuclei have similar cell types, which closely resemble cells in the cerebral cortex. Therefore, we suggest that what is known about cortical circuitry can be used as a guide for studying synaptic circuitry in the lateral and basolateral nuclei ...
O E, Millhouse, J, DeOlmos
openaire   +2 more sources