Results 221 to 230 of about 3,828,364 (261)

Visual detection of microRNA with lateral flow nucleic acid biosensor [PDF]

open access: yesBiosensors and Bioelectronics, 2014
We report a DNA-gold nanoparticle (DNA-GNP) based lateral flow nucleic acid biosensor for visual detection of microRNA (miRNA)-215 in aqueous solutions and biological samples with low-cost and short analysis time. Sandwich-type hybridization reactions among GNP-labeled DNA probe, miRNA-215 and biotin-modified DNA probes were performed on the lateral ...
Xue Zhang, Li-Ping Xu, Xuefei Gao
exaly   +3 more sources

Nanoparticle-based lateral flow biosensors [PDF]

open access: yesBiosensors and Bioelectronics, 2015
Lateral flow biosensors (LFBs) are paper-based devices which permit the performance of low-cost and fast diagnostics with good robustness, specificity, sensitivity and low limits of detection. The use of nanoparticles (NPs) as labels play an important role in the design and fabrication of a lateral flow strip (LFS).
Arben Mërkoçi   +1 more
exaly   +5 more sources

Biosensors, microfluidics systems and lateral flow assays for circulating microRNA detection: A review

Analytical Biochemistry, 2021
MicroRNAs (miRNAs) are short RNA sequences found in eukaryotic cells and they are involved in several diseases pathogenesis including different types of cancers, metabolic and cardiovascular disorders. Thus, miRNAs circulating in serum, plasma, and other body fluids are employed as biomarkers for diagnostic and prognostic purposes and in assessment of ...
Niloofar, Khandan-Nasab   +5 more
openaire   +2 more sources

An enzyme-amplified lateral flow strip biosensor for visual detection of MicroRNA-224

Talanta, 2016
An enzyme-based dual-labeled nanoprobe is designed to fabricate a sensitive enzyme-amplified lateral flow biosensor for visual detection of mircoRNA-224 (miRNA-224). The recognition DNA probe (detection probe) and signal amplification enzyme (Horseradish peroxidase, HRP) are immobilized on gold nanoparticle (GNPs) surface, simultaneously.
Xue Zhang, Xinlei Ma, Yongqiang Wen
exaly   +3 more sources

Convolutional Neural Network for Accurate Analysis of Methamphetamine With Upconversion Lateral Flow Biosensor

IEEE Transactions on NanoBioscience, 2023
Methamphetamine is a powerful stimulant drug, the abuse of which threatens human health and social stability. Rapid and accurate quantification of methamphetamine is essential to inhibit the abuse and prevalence of methamphetamine effectively. In this paper, we present a portable fluorescence reader with upconverting nanoparticle-labeled lateral flow ...
Lei Huang   +5 more
openaire   +2 more sources

Multiplexed lateral flow biosensors: Technological advances for radically improving point-of-care diagnoses

open access: yesBiosensors and Bioelectronics, 2016
Lateral flow biosensors are a leading technology in point-of-care diagnostics due to their simplicity, rapidness and low cost. Their primacy in this arena continues through technological breakthroughs such as multiplexing: the detection of more than one biomarker in a single assay.
Jia Li, Joanne Macdonald
exaly   +4 more sources

A fluorescent lateral flow biosensor for the quantitative detection of Vaspin using upconverting nanoparticles

Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2020
Vaspin is a protein present in human serum that can cause type-2 diabetes, obesity, and other cardiovascular diseases. We report fluorescent upconverting nanoparticles (UCNPs)-based lateral flow biosensor for ultrasensitive detection of Vaspin. A pair (primary and secondary) of cognate aptamers was used that has duo binding with Vaspin.
Muhammad Asad Ullah Khalid   +2 more
exaly   +3 more sources

Gold nanorods-based lateral flow biosensors for sensitive detection of nucleic acids

Microchimica Acta, 2021
A gold nanorod (AuNR)-based lateral flow nucleic acid biosensor (LFNAB) is reported for visual detection of DNA with a short test time and high sensitivity. AuNRs with an approximate length of 60 nm were utilized as a colored tag to label the detection DNA probe (Det-DNA).
Qingcai Yu   +6 more
openaire   +2 more sources

A lateral flow biosensor for rapid detection of DNA-binding protein c-jun

Biosensors and Bioelectronics, 2011
A lateral flow biosensor based on an immuno-chromatographic assay has been developed for the detection of DNA-binding proteins. The biosensor is composed of four parts: a sample pad, a conjugate pad, a strip of nitrocellulose membrane and an absorbent pad.
Lingwen Zeng, Puchang Lie, Chenchen Ge
exaly   +3 more sources

Lateral Flow Biosensors for the Detection of Nucleic Acid

2013
The detection of nucleic acid is of central importance for the diagnosis of genetic diseases, infectious agents, and biowarfare agents. Traditional strategies and technologies for nucleic acid detection are time-consuming and labor-intensive. Recently, isothermal strand-displacement reaction-based lateral flow biosensors have attracted a great deal of ...
Lingwen, Zeng   +3 more
openaire   +2 more sources

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