Comparative genomic study of the Penicillium genus elucidates a diverse pangenome and 15 lateral gene transfer events. [PDF]
IMA Fungus, 2023 Petersen C +7 more
europepmc +1 more source
Rates of Lateral Gene Transfer in Prokaryotes: High but Why?
Trends in Microbiology, 2015 Lateral gene transfer is of fundamental importance to the evolution of prokaryote genomes and has important practical consequences, as evidenced by the rapid dissemination of antibiotic resistance and virulence determinants. Relatively little effort has so far been devoted to explicitly quantifying the rate at which accessory genes are taken up and ...
Vos, Michiel +4 more
openaire +6 more sources
Advanced Healthcare Materials, EarlyView.This study presents the development of large‐scale (15 cm2) cartilage constructs with anisotropic mechanical properties using melt electrowritten (MEW) microfiber reinforced cell‐laden gelatin methacryloyl (gelMA). These constructs mimic the mechanical behavior of native cartilage, providing a suitable environment for Articular Cartilage ...
Lennard Spauwen +5 more
wiley +1 more source
Describing ancient horizontal gene transfers at the nucleotide and gene levels by comparative pathogenicity island genometrics [PDF]
, 2017 Motivation: Lateral gene transfer is a major mechanism contributing to bacterial genome dynamics and pathovar emergence via pathogenicity island (PAI) spreading.
Collyn, F. +4 more
core
Immunosuppressive Formulations for Immunological Defense against Traumatic Brain Injury
Advanced Healthcare Materials, EarlyView.A novel subcutaneous formulation combining alpha‐ketoglutarate, glycolysis inhibitor PFK15, and a myelin peptide reduces inflammation in a mouse TBI model. This formulation promotes regulatory immune cells, enhances autophagy, and improves motor function, suggesting its potential as a prophylactic immunosuppressive therapy to mitigate TBI‐induced ...
Kelly Lintecum +28 more
wiley +1 more source
Repeat sequences limit the effectiveness of lateral gene transfer and favored the evolution of meiotic sex in early eukaryotes. [PDF]
Proc Natl Acad Sci U S A, 2022 Colnaghi M, Lane N, Pomiankowski A.
europepmc +1 more source
Lateral gene transfer and parallel evolution in the history of glutathione biosynthesis genes [PDF]
, 2002 Shelley D. Copley, Jasvinder K Dhillon
openalex +1 more source
Reconstructing an ancestral genotype of two hexachlorocyclohexane-degrading Sphingobium species using metagenomic sequence data. [PDF]
, 2014 Over the last 60 years, the use of hexachlorocyclohexane (HCH) as a pesticide has resulted in the production of >4 million tons of HCH waste, which has been dumped in open sinks across the globe.
Gilbert, Jack A +8 more
core
Advanced Healthcare Materials, EarlyView.A mechanically active OsteoChondral Unit (OCU)‐on‐Chip platform mimicking the OCU's functional anatomy and the strain gradient across the osteochondral interface is presented. Upon compartment‐specific hyperphysiological compression, the model replicates mechanisms observed in osteoarthritis (OA) progression, such as calcium crystal accumulation ...
Andrea Mainardi +10 more
wiley +1 more source
Journal of Parasitology Research, 2016 Horizontal gene transfer has proved to be relevant in eukaryotic evolution, as it has been found more often than expected and related to adaptation to certain niches.
Miguel Romero +2 more
doaj +1 more source