Results 81 to 90 of about 230,314 (320)

Unifying Parsimonious Tree Reconciliation

open access: yes, 2013
Evolution is a process that is influenced by various environmental factors, e.g. the interactions between different species, genes, and biogeographical properties.
A.C. Berglund-Sonnhammer   +28 more
core   +1 more source

The emergence and fate of horizontally acquired genes in Escherichia coli [PDF]

open access: yes, 2008
Bacterial species, and even strains within species, can vary greatly in their gene contents and metabolic capabilities. We examine the evolution of this diversity by assessing the distribution and ancestry of each gene in 13 sequenced isolates of ...
Marri, P.R.   +2 more
core   +4 more sources

Dorsolateral Cervical Cord T2 Hyperintensity in KIF1C‐Related Disease (Spastic Paraplegia 58): Two Long‐Duration Cases

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Pathogenic variants in KIF1C cause Spastic Paraplegia 58 (SPG58), typically presenting with cerebellar ataxia and spastic paraparesis. We report two unrelated patients with spastic paraparesis, cerebellar ataxia, and tremor. Whole‐exome sequence analysis identified novel homozygous variants in the motor domain of KIF1C (NM_006612.6): c.921G>A (
Akihiko Mitsutake   +12 more
wiley   +1 more source

A complex and punctate distribution of three eukaryotic genes derived by lateral gene transfer

open access: yesBMC Evolutionary Biology, 2007
Background Lateral gene transfer is increasingly invoked to explain phylogenetic results that conflict with our understanding of organismal relationships. In eukaryotes, the most common observation interpreted in this way is the appearance of a bacterial
Durnford Dion G   +5 more
doaj   +1 more source

Novel Mobile Integrons and Strain-Specific Integrase Genes within Shewanella spp. Unveil Multiple Lateral Genetic Transfer Events within The Genus [PDF]

open access: gold, 2022
Teolincacihuatl Ayala Nuñez   +4 more
openalex   +1 more source

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons   +31 more
wiley   +1 more source

Lateral gene exchanges shape the genomes of amoeba-resisting microorganisms

open access: yesFrontiers in Cellular and Infection Microbiology, 2012
Based on Darwin’s concept of the tree of life, vertical inheritance was thought to be dominant, and mutations, deletions and duplication were streaming the genomes of living organisms.
Claire eBertelli, Gilbert eGreub
doaj   +1 more source

Unexpected evolutionary proximity of eukaryotic and cyanobacterial enzymes responsible for biosynthesis of retinoic acid and its oxidation [PDF]

open access: yes, 2014
Biosynthesis of retinoic acid from retinaldehyde (retinal) is catalysed by an aldehyde dehydrogenase (ALDH) and its oxidation by cytochrome P450 enzymes (CYPs).
Gallagher, Connor   +4 more
core   +1 more source

Lateral gene transfer in the subsurface [PDF]

open access: yes, 2007
Lateral gene transfer (LGT) is an important adaptive mechanism among prokaryotic organisms. This mechanism is particularly important for the response of microorganisms to changing environmental conditions because it facilitates the transfer of a large number of genes and their rapid expression.
Barkay, Tamar, Sobecky, Patricia
openaire   +2 more sources

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