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The Cognitive (Lateral) Hypothalamus [PDF]

open access: yesTrends in Cognitive Sciences, 2023
Despite the physiological complexity of hypothalamus, its role is typically restricted to initiation or cessation of innate behaviors. For example, theories of lateral hypothalamus argue it is a switch to turn feeding “on” and “off” as dictated by higher-
Melissa Sharpe
exaly   +5 more sources

Lateral-medial dissociation in orbitofrontal cortex-hypothalamus connectivity [PDF]

open access: yesFrontiers in Human Neuroscience, 2016
The orbitofrontal cortex (OFC) is involved in cognitive functions, and is also closely related to autonomic functions. The OFC is densely connected with the hypothalamus, a heterogeneous structure controlling autonomic functions that can be divided into ...
Satoshi eHirose   +10 more
doaj   +6 more sources

The Role of the Lateral Hypothalamus in Violent Intraspecific Aggression—The Glucocorticoid Deficit Hypothesis

open access: yesFrontiers in Systems Neuroscience, 2018
This review argues for a central role of the lateral hypothalamus in those deviant forms of aggression, which result from chronic glucocorticoid deficiency.
József Haller, József Haller
doaj   +3 more sources

Loss of the Metabolism and Sleep Regulating Neuronal Populations Expressing Orexin and Oxytocin in the Hypothalamus in Amyotrophic Lateral Sclerosis

open access: yesNeuropathology and Applied Neurobiology, 2021
To determine the underlying cellular changes and clinical correlates associated with pathology of the hypothalamus in amyotrophic lateral sclerosis (ALS), as hypothalamic atrophy occurs in the preclinical phase of the disease.
Asa Petersen, Rebekah M Ahmed
exaly   +4 more sources

Resting State Functional Connectivity of the Lateral and Medial Hypothalamus in Cocaine Dependence: An Exploratory Study [PDF]

open access: yesFrontiers in Psychiatry, 2018
The role of dopamine in cocaine misuse has been extensively documented for the mesocorticolimbic circuit. Preclinical work from earlier lesion studies to recent multidisciplinary investigations has suggested that the hypothalamus is critically involved ...
Sheng Zhang   +6 more
doaj   +3 more sources

The Integrated Function of the Lateral Hypothalamus in Energy Homeostasis [PDF]

open access: yesCells
The lateral hypothalamic area (LHA) serves as a central integrative hub for the regulation of energy homeostasis and motivational behaviors, including feeding and arousal.
Xiangtong Chen   +6 more
doaj   +4 more sources

Nucleus accumbens circuit disinhibits lateral hypothalamus glutamatergic neurons contributing to morphine withdrawal memory in male mice

open access: yesNature Communications, 2023
Lateral hypothalamus (LH) plays an role in drug addiction. Here, authors present evidence for disinhibited LH glutamatergic neurons by neural circuits from nucleus accumbens to contribute to context-induced expression of morphine withdrawal memory.
Huan Sheng   +15 more
doaj   +2 more sources

Sex-associated circadian signaling signatures in the lateral hypothalamus [PDF]

open access: yesFrontiers in Sleep
IntroductionThe lateral hypothalamus (LH) is a central integrative hub coordinating arousal, feeding, metabolism, stress responsiveness, and sleep-wake state transitions.
Sara K. Pintwala, Patrick M. Fuller
doaj   +2 more sources

Prelimbic area to lateral hypothalamus circuit drives social aggression [PDF]

open access: yesiScience, 2023
Summary: Controlling aggression is a vital skill in social species such as rodents and humans and has been associated with the medial prefrontal cortex (mPFC). In this study, we showed that during aggressive behavior, the activity of GABAergic neurons in
Fuhai Bai   +16 more
doaj   +2 more sources

Lateral Hypothalamus as a Motivation-Cognition Interface in the Control of Feeding Behavior

open access: yesFrontiers in Systems Neuroscience, 2018
Converging evidence for an essential function of the lateral hypothalamus (LHA) in the control of feeding behavior has been accumulating since the classic work conducted almost 80 years ago. The LHA is also important in reward and reinforcement processes
Gorica D. Petrovich
doaj   +2 more sources

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