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Glutamatergic lateral hypothalamus promotes defensive behaviors.
Neuropharmacology, 2020The glutamatergic lateral hypothalamus (LH) has been implicated in a variety of behaviors, such as evasion and feeding, while its role in defensive behaviors and relevant neurocircuits remains unclear.
Li Chen +15 more
semanticscholar +3 more sources
The lateral hypothalamus: a site for integration of nutrient and fluid balance.
Behavioral Brain Research, 2011 This paper reviews seemingly obligatory relations between nutrient and fluid balance. A relatively novel neuronal pathway involving interplay between acetylcholine and the melanocortins, alpha MSH and AGRP in the arcuate nucleus (Arc) of the hypothalamus projecting to the lateral hypothalamus (LH) may bridge this gap. In the fasted condition, increased
G. van Dijk +5 more
semanticscholar +4 more sources
Regulation of wakefulness by astrocytes in the lateral hypothalamus
Neuropharmacology, 2022The lateral hypothalamus (LH) is an important brain region mediating sleep-wake behavior. Recent evidence has shown that astrocytes in central nervous system modulate the activity of adjacent neurons and participate in several physiological functions. However, the role of LH astrocytes in sleep-wake regulation remains unclear.
Ping Cai +17 more
openaire +2 more sources
Lateral Hypothalamus: Site Involved in Pain Modulation
Neuroscience, 1996The present study is an attempt to examine the neuronal circuitry of a supraspinal site engaged in pain modulation. Five physiological measures were postulated as the criteria for defining a central nervous system site engaged in the circuitry of pain modulation.
Nachum Dafny +2 more
exaly +3 more sources
Projections of the septum to the lateral hypothalamus
Experimental Neurology, 1972Abstract Evoked potentials recorded in the lateral hypothalamus (LH) of the rat to stimulation of the septum were observed to have response components of 3–6, 10–14, and 18–23 msec. These components were elicited from different regions of the septum; the 3–6 and 10–14 msec components from dorsal and midline regions corresponding to the projection ...
J J, Miller, G J, Mogenson
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Does the ventromedial hypothalamus inhibit the lateral hypothalamus?
Physiology & Behavior, 1974Abstract Electrical stimulation of the ventromedial hypothalamus inhibited feeding in hungry rats. Neither knife cuts of the VMH-LH connections nor LH electrolytic lesions significantly altered the feeding inhibitory effects of medial stimulation.
A, Sclafani, G, Maul
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Development of the GABAergic and glutamatergic neurons of the lateral hypothalamus
Journal of Chemical Neuroanatomy, 2021In the last few years we assist to an unexpected deluge of genomic data on hypothalamic development and structure. Perhaps most surprisingly, the Lateral Zone has received much attention too. The new information focuses first of all on transcriptional heterogeneity.
Zhou, Xunlei +2 more
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Lateralization of LH-RH in rat hypothalamus
Brain Research, 1984An asymmetrical LH-RH distribution in rat hypothalamus has been found. In Wistar rats LH-RH content in the right hypothalamus exceeds that in the left one; in albino rats a contrary distribution is observed. LH-RH lateralization changes during a 24-h period. Unilateral castration or cold stress lead to a shift in LH-RH distribution in the hypothalamus.
, Bakalkin GYa +5 more
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Hypothalamus and weight loss in amyotrophic lateral sclerosis
2021Amyotrophic lateral sclerosis (ALS) is a devastating progressive neurodegenerative disorder. While initially pathophysiology was thought to be restricted to motor deficits, it is increasingly recognized that patients develop prominent changes in weight and eating behavior that result from and mediate the underlying neurodegenerative process.
Ahmed, Rebekah M. +2 more
openaire +4 more sources