Results 101 to 110 of about 2,892 (211)
Journal of Lipid Research, 1996 Mechanisms of hyperlipidemia were studied by measurement of serum lipid concentrations and the ratios of cholesterol precursors (squalene, delta 8-cholestenol, desmosterol, and lathosterol), plant sterols (campesterol and sitosterol), and cholestanol (a ...
K Nikkilä +3 more
doaj +1 more source
Veterinary and Comparative Oncology, Volume 23, Issue 3, Page 388-400, September 2025.ABSTRACT Chemotherapy can have adverse gastrointestinal effects in dogs and people. The objective of this study was to assess the impact of vincristine and prednisolone/prednisone, as part of a CHOP chemotherapy [cyclophosphamide, hydroxydaunorubicin, oncovin (vincristine) and prednisolone/prednisone] protocol, on gastrointestinal dysbiosis in dogs ...
Juan Aragon +10 more
wiley +1 more source
The relationships of markers of cholesterol homeostasis with carotid intima-media thickness.
PLoS ONE, 2010 BackgroundThe relationship of cholesterol homeostasis and carotid intima-media thickness (cIMT) is unknown. To address this, we assessed markers of cholesterol homeostasis (serum plant sterols and cholesterol precursor concentrations as surrogate ...
Oliver Weingärtner +12 more
doaj +1 more source
RETRACTED ARTICLE: Age-dependent Increase in Desmosterol Restores DRM Formation and Membrane-related Functions in Cholesterol-free DHCR24−/− Mice [PDF]
, 2018 Cholesterol is a prominent modulator of the integrity and functional activity of physiological membranes and the most abundant sterol in the mammalian brain. DHCR24-knock-out mice lack cholesterol and accumulate desmosterol with age.
Crameri, Arames +11 more
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Journal of Lipid Research, 1966 Methods were developed for the separation and determination of the various 27-carbon sterols of intestinal mucosa by means of thin-layer chromatography.
Robert K. Ockner, Leonard Laster
doaj +1 more source
Profile of cholesterol-related sterols in aged amyloid precursor protein transgenic mouse brain
Journal of Lipid Research, 2002 Cholesterol is implicated to play a role in Alzheimer disease pathology. Therefore, the concentrations of cholesterol, its precursors, and its degradation products in brain homogenates of aging wild-type and β-amyloid precursor protein transgenic mice ...
Dieter Lütjohann +8 more
doaj +1 more source
Effects of vitamin D on serum lipid profile in patients with type 2 diabetes: A meta-analysis of randomized controlled trials [PDF]
, 2016 Background & aims The effect of vitamin D on lipid profile in type 2 diabetic patients is controversial. This meta-analysis aimed to assess the effect of vitamin D on serum total cholesterol (TC), triglycerides (TG), low-density lipoproteins (LDL), and ...
Barani, Afshin. +2 more
core +1 more source
Accumulation of cholesterol precursors and plant sterols in human stenotic aortic valves
Journal of Lipid Research, 2008 The pathogenesis of aortic valve stenosis (AS) is characterized by the accumulation of LDL-derived cholesterol in the diseased valves. Since LDL particles also contain plant sterols, we investigated whether plant sterols accumulate in aortic valve ...
Satu Helske +8 more
doaj +1 more source
Journal of Lipid Research, 2010 Proprotein convertase, subtilisin/kexin type 9 (PCSK9), a key regulator of plasma LDL-cholesterol (LDL-c) and cardiovascular risk, is produced in liver and secreted into plasma where it binds hepatic LDL receptors (LDLR), leading to their degradation ...
Jeffrey D. Browning, Jay D. Horton
doaj +1 more source
A detailed genome-wide reconstruction of mouse metabolism based on human Recon 1 [PDF]
, 2010 Background Well-curated and validated network reconstructions are extremely valuable tools in systems biology. Detailed metabolic reconstructions of mammals have recently emerged, including human reconstructions.
Bernhard Ø Palsson +4 more
core +2 more sources