Vitamin D in plants: a review of occurrence, analysis, and biosynthesis. [PDF]
, 2013 The major function of vitamin D in vertebrates is maintenance of calcium homeostasis, but vitamin D insufficiency has also been linked to an increased risk of hypertension, autoimmune diseases, diabetes and cancer. Therefore, there is a growing awareness
Jakobsen, Jette, Jäpelt, Rie Bak
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Phytosterolemia on the island of Kosrae
Journal of Lipid Research, 2004 Screening of 932 adults on the Pacific island of Kosrae for plasma plant sterol levels disclosed three subjects, two of them asymptomatic, with phytosterolemia. Sequencing the ATP binding cassette subfamily G member 8 (ABCG8) gene revealed a novel exon 2
Ephraim Sehayek +10 more
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Separations, 2018 Oxysterols are metabolites produced in the first step of cholesterol metabolism, which is related to neurodegenerative disorder. They can be detected by testing blood, plasma, serum, or cerebrospinal fluid.
Lucia Valverde-Som +7 more
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The interrelations between PCSK9 metabolism and cholesterol synthesis and absorption
Journal of Lipid Research, 2019 Very few studies have investigated the interrelations between proprotein convertase subtilisin/kexin type 9 (PCSK9) metabolism, cholesterol synthesis, and cholesterol absorption.
Günther Silbernagel +11 more
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Sterol metabolism. 6. The interconversion of cholesterol, 7-dehydrocholesterol and lathosterol in the rat [PDF]
Biochemical Journal, 1961 E I, MERCER, J, GLOVER
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Localization of the pre-squalene segment of the isoprenoid biosynthetic pathway in mammalian peroxisomes [PDF]
, 2018 Previous studies have indicated that the early steps in the isoprenoid/cholesterol biosynthetic pathway occur in peroxisomes. However, the role of peroxisomes in cholesterol biosynthesis has recently been questioned in several reports concluding that ...
Brunengraber, Henri +7 more
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RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype. [PDF]
, 2019 Tumor subtype-specific metabolic reprogrammers could serve as targets of therapeutic intervention. Here we show that triple-negative breast cancer (TNBC) exhibits a hyper-activated cholesterol-biosynthesis program that is strongly linked to nuclear ...
Bold, Richard J +21 more
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Cholesterol Absorption and Synthesis Markers: Risk for Cardiovascular Diseases? [PDF]
J Atheroscler Thromb, 2023 Minami M.
europepmc +1 more source
Drug interaction potential of 2-((3,4-dichlorophenethyl)(propyl)amino)-1-(pyridin-3-yl)ethanol (LK-935), the novel nonstatin-type cholesterol-lowering agent [PDF]
, 2014 Acimovic J +11 more
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Diagnostic Fragmentations of Animal and Fungal Sterols/Stanols Obtained by APCI-Tandem Mass Spectrometry: A Route Towards Unknown Free Sterol Identification. [PDF]
MetabolitesCinquepalmi V +4 more
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