Results 1 to 10 of about 60,760 (368)
BMC Geriatrics, 2023 Background Constipation was associated with incidence of dementia and cognitive decline. Laxatives are the mainstay of constipation management and are commonly used among older populations for both treatment and prevention of constipation.
Jiangtao Feng +6 more
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Review article: do stimulant laxatives damage the gut? A critical analysis of current knowledge
Therapeutic Advances in GastroenterologyStimulant laxatives are well established as first- or second-line treatments for constipation and although they have a reliable therapeutic effect, alleged safety concerns still exist, particularly with long-term use. The potential harmful effects on the
Peter Whorwell +2 more
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BMC Gastroenterology, 2022 Background Many older patients experience constipation as a bothersome symptom with a negative impact on quality of life. During hospitalization, the focus is often on the reason for admission with the risk that other health problems are not prioritized.
Hanne Konradsen +3 more
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Evaluating high dose laxatives via nasogastric tube versus enemas in children with severe constipation: a prospective cohort study [PDF]
BMC PediatricsObjectives Children with severe constipation often require disimpaction when standard treatments fail, typically involving high doses of oral laxatives or rectal enemas. Practice guidelines for nurses lack clear directives.
Marion A. Meester–Soonius +4 more
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Impact of antipsychotics, antiparkinsonian drugs, and anthraquinone stimulant laxatives on severe constipation in patients with schizophrenia [PDF]
PCN ReportsAim Constipation in schizophrenia patients receiving antipsychotics can lead to severe intestinal complications, such as paralytic ileus or megacolon. Despite the clinical importance of the topic, few studies have thoroughly investigated the risk factors
Toshiaki Nadaya +3 more
doaj +2 more sources
The macrogol revolution in the treatment of chronic constipation. A short history of laxatives [PDF]
Frontiers in PharmacologyThe difficulty of treating constipation has accompanied humanity through the centuries. Until 1990, numerous remedies were proposed to alleviate the condition; however, due to their aggressive nature or side effects, they were mainly used occasionally or
Enrico Stefano Corazziari
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A clinical decision support alert to promote timely laxative use in in-patients prescribed clozapine [PDF]
BJPsych OpenBackground Clozapine-induced gastrointestinal hypomotility and constipation can result in severe and sometimes fatal gastrointestinal complications.
Milan Sundermann +3 more
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Considerations for laxatives in terms of their interactions with other drugs
Expert Opinion on Drug Metabolism & Toxicology, 2023 Laxatives represent the main treatment for constipated subjects since ancient times [1], are among the most frequently used drugs worldwide, and impose a substantial economic burden on both patients and health-care systems [2].
G. Bassotti, E. Battaglia
semanticscholar +1 more source
Phytotherapy Research, 2022 This systematic review and meta‐analysis were conducted to determine the effects of anthraquinone (AQ) laxatives on colorectal cancer (CRC). We searched PubMed, Embase, Google Scholar, and CENTRAL from inception until March 2021, for randomized ...
N. Lombardi +15 more
semanticscholar +1 more source
Asian Pacific Journal of Cancer Prevention, 2022 Background: Prophylactic laxatives were associated with decreasing the incidence of Opioid-induced constipation among patients with cancer. This study aims to evaluate the effectiveness of early prophylactic laxatives therapy on the severity of ...
Muayyad M. Ahmad, M. Alnaeem
semanticscholar +1 more source