Results 11 to 20 of about 1,796 (169)

Bridging the species divide: The limits of rat models in capturing human PVOD mechanisms [PDF]

Pulmonary Circulation
Pulmonary Circulation, Volume 14, Issue 4, October 2024.
Frédéric Perros, Cédric Chaveroux, David Montani   +2 more
doaj   +3 more sources

How Does Technology Import and Export Affect the Innovative Performance of Firms? From the Perspective of Emerging Markets Firms

Complexity, 2020
As economic globalization develops greatly in recent years, emerging market firms (EMFs) increasingly grasp the opportunity of cross-border learning to develop and improve their technology capability through learning by exporting (LBE) and learning by ...
Kui Wang, Jintang Wang, Shiye Mei, Shasha Xiong   +3 more
doaj   +2 more sources

Fabrication of self-emulsifying lipid microstructure by stiffness-tunable mold for drug delivery applications [PDF]

Microsystems & Nanoengineering
Amphiphilic lipid formulations, such as self-emulsifying drug delivery systems, offer advantages for enhancing drug release control and expanding their applicability across various administration routes.
Jongeon Park, Renaud Rovera, Arnaud Bertsch, Nicolas Zaugg, Hiba Hassoun, Evelyne Colomb, Claire Monge, Juergen Brugger   +7 more
doaj   +2 more sources

THE GRAY NEEDLE: LARGE GRAINS IN THE HD 15115 DEBRIS DISK FROM LBT/PISCES/KsAND LBTI /LMIRcam/L′ ADAPTIVE OPTICS IMAGING [PDF]

The Astrophysical Journal, 2012
We present diffraction-limited \ks band and \lprime adaptive optics images of the edge-on debris disk around the nearby F2 star HD 15115, obtained with a single 8.4 m primary mirror at the Large Binocular Telescope. At \ks band the disk is detected at signal-to-noise per resolution element (SNRE) \about 3-8 from \about 1-2\fasec 5 (45-113 AU) on the ...
Rodigas, Timothy J., Hinz, Philip M., Leisenring, Jarron, Vaitheeswaran, Vidhya, Skemer, Andrew J., Skrutskie, Michael, Su, Kate Y. L., Bailey, Vanessa, Schneider, Glenn, Close, Laird, Mannucci, Filippo, Esposito, Simone, Arcidiacono, Carmelo, Pinna, Enrico, Argomedo, Javier, Agapito, Guido, Apai, Daniel, Bono, Giuseppe, Boutsia, Kostantina, Briguglio, Runa, Brusa, Guido, Busoni, Lorenzo, Cresci, Giovanni, Currie, Thayne, Desidera, Silvano, Eisner, Josh, Falomo, Renato, Fini, Luca, Follette, Kate, Fontana, Adriano, Garnavich, Peter, Gratton, Raffaele, Green, Richard, Guerra, Juan Carlos, Hill, J. M., Hoffmann, William F., Jones, Terry Jay, Krejny, Megan, Kulesa, Craig, Males, Jared, Masciadri, Elena, Mesa, Dino, McCarthy, Don, Meyer, Michael, Miller, Doug, Nelson, Matthew J., Puglisi, Alfio, Quiros-Pacheco, Fernando, Riccardi, Armando, Sani, Eleonora, Stefanini, Paolo, Testa, Vincenzo, Wilson, John, Woodward, Charles E., Xompero, Marco   +54 more
openaire   +3 more sources

Latent tuberculosis infection (LTBI) in health-care workers: a cross-sectional study at a northern Peruvian hospital [PDF]

Frontiers in Medicine, 2023
BackgroundHealthcare workers (HCWs) have a higher risk of latent tuberculosis infection (LTBI) and active tuberculosis than the general population.
Edinson Dante Meregildo-Rodriguez, Verónica Yuptón-Chávez, Martha Genara Asmat-Rubio, Gustavo Adolfo Vásquez-Tirado   +3 more
doaj   +2 more sources

The Linoleic Acid Content of the Stratum Corneum of Ichthyotic Golden Retriever Dogs Is Reduced as Compared to Healthy Dogs and a Significant Part Is Oxidized in Both Free and Esterified Forms [PDF]

Metabolites, 2021
Golden Retrievers may suffer from Pnpl1-related inherited ichthyosis. Our study shows that in the stratum corneum (SC) of ichthyotic dogs, linoleic acid (LA) is also present in the form of 9-keto-octadecadienoic acid (9-KODE) instead of the acylacid form
Iuliana Popa, Audrey Solgadi, Didier Pin, Adrian L. Watson, Marek Haftek, Jacques Portoukalian   +5 more
doaj   +2 more sources

Skin Cell and Tissue Responses to Cross-Linked Hyaluronic Acid in Low-Grade Inflammatory Conditions. [PDF]

Int J Inflam, 2023
Hyaluronic acid (HA), used in a variety of medical applications, is associated in rare instances to long‐term adverse effects. Although the aetiology of these events is unknown, a number of hypotheses have been proposed, including low molecular weight of HA (LMW‐HA) in the filler products.
Sanchez B, Ferraro S, Josset-Lamaugarny A, Pagnon A, Hee CK, Nakab L, Sigaudo-Roussel D, Fromy B.   +7 more
europepmc   +2 more sources

Preclinical efficacy of carfilzomib in BRAF‐mutant colorectal cancer models

Molecular Oncology
Serine/threonine‐protein kinase B‐raf (BRAF) mutations are found in 8–15% of colorectal cancer patients and identify a subset of tumors with poor outcome in the metastatic setting.
Federica Maione, Daniele Oddo, Federica Galvagno, Chiara Falcomatà, Marta Pandini, Marco Macagno, Valeria Pessei, Ludovic Barault, Chiara Gigliotti, Alessia Mira, Giorgio Corti, Simona Lamba, Chiara Riganti, Barbara Castella, Massimo Massaia, Roland Rad, Dieter Saur, Alberto Bardelli, Federica Di Nicolantonio   +18 more
doaj   +2 more sources

Rhodamine6G and Hœchst33342 narrow BmrA conformational spectrum for a more efficient use of ATP [PDF]

Nature Communications
Multidrug ABC transporters harness the energy of ATP binding and hydrolysis to translocate substrates out of the cell and detoxify them. While this involves a well-accepted alternating access mechanism, molecular details of this interplay are still ...
A. Gobet, L. Moissonnier, E. Zarkadas, S. Magnard, E. Bettler, J. Martin, R. Terreux, G. Schoehn, C. Orelle, JM Jault, P. Falson, V. Chaptal   +11 more
doaj   +2 more sources

Hierarchical Poromechanical Approach to Investigate the Impact of Mechanical Loading on Human Skin Micro-Circulation. [PDF]

Int J Numer Method Biomed Eng
A hierarchical poromechanical theory was developed to model human skin, separately accounting for interstitial fluid and cell characteristic times. Implemented in FEniCSx, it was validated through laser Doppler flowmetry experiments. To ensure transparency, all data and codes are publicly available on GitHub, combining theory, numerical validation, and
Lavigne T, Urcun S, Fromy B, Josset-Lamaugarny A, Lagache A, Suarez-Afanador CA, Bordas SPA, Rohan PY, Sciumè G.   +8 more
europepmc   +2 more sources