Results 31 to 40 of about 1,796 (169)

Glycation by glyoxal leads to profound changes in the behavior of dermal fibroblasts

BMJ Open Diabetes Research & Care, 2021
Introduction Diabetes is a worldwide health problem that is associated with severe complications. Advanced Glycation End products (AGEs) such as Nε-(carboxymethyl)lysine, which result from chronic hyperglycemia, accumulate in the skin of patients with ...
Cécile Guillon, Sandra Ferraro, Sophie Clément, Marielle Bouschbacher, Dominique Sigaudo-Roussel, Christelle Bonod   +5 more
doaj   +1 more source

Stroma Involvement in Pancreatic Ductal Adenocarcinoma: An Overview Focusing on Extracellular Matrix Proteins

Frontiers in Immunology, 2021
Pancreatic cancer is the seventh leading cause of cancer-related deaths worldwide and is predicted to become second in 2030 in industrialized countries if no therapeutic progress is made. Among the different types of pancreatic cancers, Pancreatic Ductal
Sophie Liot, Jonathan Balas, Alexandre Aubert, Laura Prigent, Perrine Mercier-Gouy, Bernard Verrier, Philippe Bertolino, Ana Hennino, Ulrich Valcourt, Elise Lambert   +9 more
doaj   +1 more source

Latent TGF-β Activation Is a Hallmark of the Tenascin Family

Frontiers in Immunology, 2021
Transforming growth factor-β (TGF-β) isoforms are secreted as inactive complexes formed through non-covalent interactions between bioactive TGF-β entities and their N-terminal pro-domains called latency-associated peptides (LAP). Extracellular activation
Alexandre Aubert, Perrine Mercier-Gouy, Stéphanie Aguero, Laurent Berthier, Sophie Liot, Laura Prigent, Lindsay B. Alcaraz, Bernard Verrier, Raphaël Terreux, Catherine Moali, Elise Lambert, Ulrich Valcourt   +11 more
doaj   +1 more source

TARGET SELECTION FOR THE LBTI EXOZODI KEY SCIENCE PROGRAM [PDF]

The Astrophysical Journal Supplement Series, 2015
The Hunt for Observable Signatures of Terrestrial planetary Systems (HOSTS) on the Large Binocular Telescope Interferometer will survey nearby stars for faint emission arising from ~300 K dust (exozodiacal dust), and aims to determine the exozodiacal dust luminosity function.
Weinberger, Alycia J., Bryden, Geoff, Kennedy, Grant M., Roberge, Aki, Defrere, Denis, Hinz, Philip M., Millan-Gabet, Rafael, Rieke, George, Bailey, Vanessa P., Danchi, William C., Haniff, Chris, Mennesson, Bertrand, Serabyn, Eugene, Skemer, Andrew J., Stapelfeldt, Karl R., Wyatt, Mark C.   +15 more
openaire   +3 more sources

Alpha-Lipoic Acid Supplementation Restores Early Age-Related Sensory and Endothelial Dysfunction in the Skin

Biomedicines, 2022
Many changes characterize skin aging, and the resulting dysfunctions still constitute a real challenge for our society. The aim of this study was to compare the skin aging of two rat strains, Wistar and Brown Norway (BN), considered as “poorly aging” and
Anne-France de Bengy, Johanna Decorps, Lisa S. Martin, Aurélie Pagnon, Fabien P. Chevalier, Dominique Sigaudo-Roussel, Bérengère Fromy   +6 more
doaj   +1 more source

Evaluating the GeoSnap 13‐μ$$ \mu $$m cutoff HgCdTe detector for mid‐IR ground‐based astronomy

Astronomische Nachrichten, Volume 344, Issue 8-9, October-November 2023., 2023
Abstract New mid‐infrared HgCdTe (MCT) detector arrays developed in collaboration with Teledyne Imaging Sensors (TIS) have paved the way for improved 10‐μ$$ \mu $$m sensors for space‐ and ground‐based observatories. Building on the successful development of longwave HAWAII‐2RGs for space missions such as NEO Surveyor, we characterize the first 13‐μ ...
Jarron M. Leisenring, Dani Atkinson, Rory Bowens, Vincent Douence, William F. Hoffmann, Michael R. Meyer, John Auyeung, James Beletic, Mario S. Cabrera, Alexandra Z. Greenbaum, Philip Hinz, Derek Ives, William J. Forrest, Craig W. McMurtry, Judith L. Pipher, Eric Viges   +15 more
wiley   +1 more source

Status of commissioning stabilized infrared Fizeau interferometry with LBTI [PDF]

Techniques and Instrumentation for Detection of Exoplanets IX, 2019
To appear in SPIE Proceedings vol.
Spalding, Eckhart, Hinz, Phil, Morzinski, Katie, Ertel, Steve, Grenz, Paul, Maier, Erin, Stone, Jordan, Vaz, Amali   +7 more
openaire   +2 more sources

Near Infrared Spectral Radiance at Multiple Wavelengths From Io's Volcanoes 1: The Low Spatial Resolution Night‐Time Galileo NIMS Data Set

Journal of Geophysical Research: Planets, Volume 128, Issue 8, August 2023., 2023
Abstract We have calculated surface‐leaving spectral radiances for 285 detections of volcanic thermal emission from Io observations made by the Galileo Near Infrared Mapping Spectrometer (NIMS) in the 0.7‐ – 5.2‐μm wavelength range, the first such analysis of the entire low‐spatial‐resolution night‐time data set.
Ashley Gerard Davies, Glenn J. Veeder
wiley   +1 more source

Combining an optimized mRNA template with a double purification process allows strong expression of in vitro transcribed mRNA

Molecular Therapy: Nucleic Acids, 2021
mRNA is a blooming technology for vaccination and has gained global attention during the SARS-CoV-2 pandemic. However, the recent clinical trials have highlighted increased reactogenicity when using high mRNA doses.
Sergio Linares-Fernández, Julien Moreno, Elise Lambert, Perrine Mercier-Gouy, Laetitia Vachez, Bernard Verrier, Jean-Yves Exposito   +6 more
doaj   +1 more source

A Polylactide-Based Micellar Adjuvant Improves the Intensity and Quality of Immune Response

Pharmaceutics, 2022
Micelles from amphiphilic polylactide-block-poly(N-acryloxysuccinimide-co-N-vinylpyrrolidone) (PLA-b-P(NAS-co-NVP)) block copolymers of 105 nm in size were characterized and evaluated in a vaccine context.
Myriam Lamrayah, Capucine Phelip, Céline Coiffier, Céline Lacroix, Thibaut Willemin, Thomas Trimaille, Bernard Verrier   +6 more
doaj   +1 more source