Micelle-Based Adjuvants for Subunit Vaccine Delivery
In the development of subunit vaccines with purified or recombinant antigens for cancer and infectious diseases, the design of improved and safe adjuvants able to efficiently target the antigen presenting cells, such as dendritic cells, represents a ...
Thomas Trimaille, Bernard Verrier
doaj +1 more source
Hi-5: A Potential High-Contrast Thermal Near-Infrared Imager for the VLTI [PDF]
Hi-5 is a high-contrast (or high dynamic range) infrared imager project for the VLTI. Its main goal is to characterize young extra-solar planetary systems and exozodiacal dust around southern main-sequence stars.
Absil, Olivier +31 more
core +3 more sources
Recent Developments in Layer‐by‐Layer Assembly for Drug Delivery and Tissue Engineering Applications
Layer‐by‐layer (LbL) films represent a powerful approach for surface functionalization and for the production of free‐standing objects. This article reviews recent applications in drug delivery and tissue engineering, coming closer to clinical applications.
João Borges +16 more
wiley +1 more source
Inhibitors of BMP‐1/tolloid‐like proteinases: efficacy, selectivity and cellular toxicity
BMP‐1/tolloid‐like proteinases belong to the astacin family of human metalloproteinases, together with meprins and ovastacin. They represent promising targets to treat or prevent a wide range of diseases such as fibrotic disorders or cancer. However, the
Maya Talantikite +8 more
doaj +1 more source
Abstract Aim We tested the hypothesis that low testosterone alters the effects of intermittent hypoxia (IH) on glucose homeostasis, hepatic oxidative stress, and transcriptomic profile in male mice. Methods We used sham‐operated or orchiectomized (ORX) mice exposed to normoxia (Nx) or IH for 2 weeks.
Gauthier Ganouna‐Cohen +8 more
wiley +1 more source
The LBTI Fizeau imager – II. Sensitivity of the PSF and the MTF to adaptive optics errors and to piston errors [PDF]
We show numerical simulations with monochromatic light in the visible for the LBTI Fizeau imager, including opto-dynamical aberrations due here to adaptive optics (AO) errors and to differential piston fluctuations, while other errors have been neglected.
Patru, F. +10 more
openaire +3 more sources
A neutrophil-dependent pathway for the generation of a neutral peptide mediator: partial characterization of components and control by alpha-1-antitrypsin. [PDF]
A biologically active neutral peptide mediator is cleaved from a plasma protein substrate by an alpha-1-antitrypsin-inhibitable serine protease apparently residing on the membrane of the human neutrophil. The peptide mediator has an approximate mol wt of
Austen, KF, Goetzl, EJ, Wintroub, BU
core
MagAO: Status and on-sky performance of the Magellan adaptive optics system
MagAO is the new adaptive optics system with visible-light and infrared science cameras, located on the 6.5-m Magellan "Clay" telescope at Las Campanas Observatory, Chile.
Biasi +24 more
core +1 more source
Abstract Background Skin wound healing is a complex mechanism which requires a lot of energy, mainly provided by mitochondrial respiration. However, little is known about the mitochondrial bioenergetics of mice skin. We sought to develop a microplate‐based assay to directly measure oxygen consumption in whole mice skin with the goal of identifying ...
Justine Dugrain +4 more
wiley +1 more source
ELT Imaging of MWC 297 from the 23 m LBTI: Complex Disk Structure and a Companion Candidate
Abstract Herbig Ae/Be stars represent the early outcomes of star formation and the initial stages of planet formation at intermediate stellar masses. Understanding both of these processes requires detailed characterization of their disk structures and companion frequencies. We present new 3.7 μm imaging of the Herbig Be star MWC 297 from
S. Sallum +5 more
openaire +2 more sources

