Results 81 to 90 of about 1,796 (169)

Micelle-Based Adjuvants for Subunit Vaccine Delivery

open access: yesVaccines, 2015
In the development of subunit vaccines with purified or recombinant antigens for cancer and infectious diseases, the design of improved and safe adjuvants able to efficiently target the antigen presenting cells, such as dendritic cells, represents a ...
Thomas Trimaille, Bernard Verrier
doaj   +1 more source

Hi-5: A Potential High-Contrast Thermal Near-Infrared Imager for the VLTI [PDF]

open access: yes, 2018
Hi-5 is a high-contrast (or high dynamic range) infrared imager project for the VLTI. Its main goal is to characterize young extra-solar planetary systems and exozodiacal dust around southern main-sequence stars.
Absil, Olivier   +31 more
core   +3 more sources

Recent Developments in Layer‐by‐Layer Assembly for Drug Delivery and Tissue Engineering Applications

open access: yesAdvanced Healthcare Materials, Volume 13, Issue 8, March 25, 2024.
Layer‐by‐layer (LbL) films represent a powerful approach for surface functionalization and for the production of free‐standing objects. This article reviews recent applications in drug delivery and tissue engineering, coming closer to clinical applications.
João Borges   +16 more
wiley   +1 more source

Inhibitors of BMP‐1/tolloid‐like proteinases: efficacy, selectivity and cellular toxicity

open access: yesFEBS Open Bio, 2018
BMP‐1/tolloid‐like proteinases belong to the astacin family of human metalloproteinases, together with meprins and ovastacin. They represent promising targets to treat or prevent a wide range of diseases such as fibrotic disorders or cancer. However, the
Maya Talantikite   +8 more
doaj   +1 more source

Loss of testosterone induces postprandial insulin resistance and increases the expression of the hepatic antioxidant flavin‐containing monooxygenases in mice exposed to intermittent hypoxia

open access: yesActa Physiologica, Volume 240, Issue 3, March 2024.
Abstract Aim We tested the hypothesis that low testosterone alters the effects of intermittent hypoxia (IH) on glucose homeostasis, hepatic oxidative stress, and transcriptomic profile in male mice. Methods We used sham‐operated or orchiectomized (ORX) mice exposed to normoxia (Nx) or IH for 2 weeks.
Gauthier Ganouna‐Cohen   +8 more
wiley   +1 more source

The LBTI Fizeau imager – II. Sensitivity of the PSF and the MTF to adaptive optics errors and to piston errors [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 2017
We show numerical simulations with monochromatic light in the visible for the LBTI Fizeau imager, including opto-dynamical aberrations due here to adaptive optics (AO) errors and to differential piston fluctuations, while other errors have been neglected.
Patru, F.   +10 more
openaire   +3 more sources

A neutrophil-dependent pathway for the generation of a neutral peptide mediator: partial characterization of components and control by alpha-1-antitrypsin. [PDF]

open access: yes, 1974
A biologically active neutral peptide mediator is cleaved from a plasma protein substrate by an alpha-1-antitrypsin-inhibitable serine protease apparently residing on the membrane of the human neutrophil. The peptide mediator has an approximate mol wt of
Austen, KF, Goetzl, EJ, Wintroub, BU
core  

MagAO: Status and on-sky performance of the Magellan adaptive optics system

open access: yes, 2014
MagAO is the new adaptive optics system with visible-light and infrared science cameras, located on the 6.5-m Magellan "Clay" telescope at Las Campanas Observatory, Chile.
Biasi   +24 more
core   +1 more source

Exploring mitochondrial metabolism of wild‐type and diabetic mice skin explants using the Seahorse technology

open access: yesSkin Research and Technology, Volume 30, Issue 3, March 2024.
Abstract Background Skin wound healing is a complex mechanism which requires a lot of energy, mainly provided by mitochondrial respiration. However, little is known about the mitochondrial bioenergetics of mice skin. We sought to develop a microplate‐based assay to directly measure oxygen consumption in whole mice skin with the goal of identifying ...
Justine Dugrain   +4 more
wiley   +1 more source

ELT Imaging of MWC 297 from the 23 m LBTI: Complex Disk Structure and a Companion Candidate

open access: yesThe Astronomical Journal, 2020
Abstract Herbig Ae/Be stars represent the early outcomes of star formation and the initial stages of planet formation at intermediate stellar masses. Understanding both of these processes requires detailed characterization of their disk structures and companion frequencies. We present new 3.7 μm imaging of the Herbig Be star MWC 297 from
S. Sallum   +5 more
openaire   +2 more sources

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