Results 191 to 200 of about 21,610 (241)

Bioaccessibility of Cafestol from Coffee Brew: A Metabolic Study Employing an In Vitro Digestion Model and LC-HRMS. [PDF]

J Agric Food Chem
Brand A, Silva A, Andriolo C, Mellinger C, Uekane T, Garrett R, Rezende C.   +6 more
europepmc   +1 more source

A pilot study of maternal vitamin D status and its association with breast milk and infant gut metabolites

Physiological Reports, Volume 14, Issue 5, March 2026.
Vitamin D status in our pilot study was associated with higher levels of certain amino acids and hexanoic acid in breast milk and metabolites in infant stool samples. Abstract Human milk contains multiple bioactive components, many of which are influenced by the mother's nutritional status.
Alyssa S. Gutierrez, Katherine E. Chetta, Santosh Thapa, Sigmund J. Haidacher, Kathleen M. Hoch, John E. Baatz, Anthony M. Haag, Numan Oezguen, Thomas D. Horvath, Carol L. Wagner, Melinda A. Engevik   +10 more
wiley   +1 more source

Safety evaluation of blue galdieria extract as a food additive

EFSA Journal, Volume 24, Issue 3, March 2026.
Abstract The EFSA Panel on Food Additive and Flavourings (FAF Panel) provides a scientific opinion on the safety of blue galdieria extract as a food additive. Blue galdieria extract is an enzymatically treated C‐phycocyanin extract derived from the lysed biomass of the microalgae Galdieria sulphuraria.
EFSA Panel on Food Additives and Flavourings (FAF), Laurence Castle, Monica Andreassen, Gabriele Aquilina, Maria Lourdes Bastos, Polly Boon, Biagio Fallico, Reginald FitzGerald, Maria Jose Frutos Fernandez, Bettina Grasl‐Kraupp, Ursula Gundert‐Remy, Rainer Gürtler, Eric Houdeau, Marcin Kurek, Henriqueta Louro, Patricia Morales, Sabina Passamonti, José Manuel Barat Baviera, Gisela Degen, David Gott, Lieve Herman, Jean‐Charles Leblanc, Peter Moldeus, Ine Waalkens‐Berendsen, Detlef Wölfle, Civitella Consuelo, Ana Maria Rincon, Alexandra Tard, Alessandra Tosato, Panagiota Zakidou, Laura Ruggeri   +30 more
wiley   +1 more source

Investigation of cisplatin-induced acute kidney injury using LC-HRMS and network pharmacology approaches in mixed <i>Curcuma longa</i> and <i>Curcuma zedoaria</i> eExtracts. [PDF]

Open Vet J
Intan PR, Alegantina S, Isnawati A, Widowati L, Sundari D, Dany F, Saputra A, Mariya SS, Sutardi LN, Setiyono A, Handharyani E.   +10 more
europepmc   +1 more source

Gram‐Scale Synthesis of an Arylsulfonamide‐Type Alkaline Phosphatase Inhibitor

ChemMedChem, Volume 21, Issue 4, 25 February 2026.
A larger amount of a tissue‐nonspecific alkaline phosphatase inhibitor, 5‐((5‐chloro‐2‐methoxyphenyl)sulfonamido)nicotinamide, was synthesized in five steps using a parallel method without the need for chromatography or crystallization. Because a single batch was used for in vivo studies in a large population of mice, the pharmacological results were ...
Zsolt Rapi, Krisztina Fülöp, Zoltán Mucsi   +2 more
wiley   +1 more source

Administration Route Differentiation of Altrenogest via the Metabolomic LC-HRMS Analysis of Equine Urine. [PDF]

Molecules
Elbourne M, Keledjian J, Cawley A, Fu S.
europepmc   +1 more source

A Facile Protocol for C(sp2)–C(sp3) Bond Formation Reactions Toward Functionalized E3 Ligase Ligands

ChemMedChem, Volume 21, Issue 4, 25 February 2026.
A robust C(sp2)–C(sp3) decarboxylative coupling strategy enables access to new CRBN ligands and degraders with improved physicochemical properties. This synthetic approach is expanding the chemical space beyond C(sp2)–N linkages, fine‐tuning proteolysis‐targeting chimera activities and unlocking previously inaccessible degrader chemotypes.
Anita Maksutova, Thomas M. Geiger, Lorenzo Cianni, Dominika E. Pieńkowska, Jan Gerhartz, Lina Read, Aleša Bricelj, Alexander Herrmann, Maurice Leon Nelles, Yuen Lam Dora Ng, Marcus D. Hartmann, Jan Krönke, Izidor Sosič, Radosław P. Nowak, Michael Gütschow, Christian Steinebach   +15 more
wiley   +1 more source

<i>Centaurea lycaonica</i> Extracts Induce Apoptosis in HeLa Human Cervical Cancer Cells via Bax/Bcl-2 Modulation and Caspase Activation: An LC-HRMS-Based Study. [PDF]

Food Sci Nutr
Karaboğa Arslan AK, Eminoğlu S, Paşayeva L, Bozkurt NM, Tugay O.   +4 more
europepmc   +1 more source

Cytotoxicity and Antimicrobial Activity of GaMF1 Analogs

ChemMedChem, Volume 21, Issue 4, 25 February 2026.
GaMF1 is a reported, highly potent inhibitor of mycobacterial ATP synthase. Structural modification of this scaffold significantly changes biological activity. We present GaMF1 analogues with strong antiparasitic effects, potential antiproliferative properties, and discuss the selectivity limitations of the parent compound and its analogues.
Jan Chasák, Petr Vyvlečka, Ivan Nemec, An Matheeussen, Natascha Van Pelt, Paul Cos, Guy Caljon, Vladimír Kryštof, Lucie Brulíková   +8 more
wiley   +1 more source

Label-Free Quantitative Proteomics Analysis of COVID-19 Vaccines by Nano LC-HRMS. [PDF]

Vaccines (Basel)
Zhao H, Li W, Liu J, Li X, Ji H, Hu M, Li M.   +6 more
europepmc   +1 more source