Results 181 to 190 of about 330,504 (280)

Plasma LC-HRMS metabolomics in parkinsonian syndromes: comparative evaluation of sample preparation protocols for exploratory metabolic signatures. [PDF]

Anal Bioanal Chem
Esposito E, Perrone A, Lopane G, Vitagliano R, Interino N, Caravelli A, Cancellerini C, Calandra-Buonaura G, Fiori J, Contin M.   +9 more
europepmc   +1 more source

Knocking Out Two Polyphenol Oxidase Genes Significantly Improves Recombinant Protein Purification in Nicotiana benthamiana

Plant Biotechnology Journal, EarlyView.
ABSTRACT Efficient purification remains a key technical challenge affecting the recovery efficiency of recombinant proteins in plant‐based systems. Complex metabolites, particularly polyphenols, often cause recombinant protein aggregation during purification.
Hai‐Ping Diao, Hui‐Xin Meng, Xue‐Jiao Xu, Zeng‐Lin Zhang, Jian‐Feng Zhang, Yong‐Feng Guo, Inhwan Hwang, Shi‐Jian Song   +7 more
wiley   +1 more source

Detection of the GH Analogue Redalsomatropin Alfa in Sports Drug Testing: Immunological Approaches and LC-HRMS/MS. [PDF]

Drug Test Anal
Walpurgis K, Thomas A, Thelen J, Majer B, Al-Jaber M, Abushareeda W, Thevis M.   +6 more
europepmc   +1 more source

Gene Editing of Nicotiana benthamiana Architecture for Space‐Efficient Production of Recombinant Proteins in Closed Environments

Plant Biotechnology Journal, EarlyView.
ABSTRACT Indoor vertical farming (VF) offers practical advantages for the cultivation of plant protein bio‐factories including plant uniformity, product consistency, water/nutrient recycling and production cycles on a year‐round basis. Much progress has been achieved toward the development of innovative systems for artificial lighting, automated ...
Béatrice Giroux, Kristina LeBreux, Louis Feyzeau, Marie‐Claire Goulet, Charles Goulet, Dominique Michaud   +5 more
wiley   +1 more source

Evaluation of MassFrontier, MetFrag, MS-FINDER, and SIRIUS for Metabolite Annotation Using an Experimental LC-HRMS Dataset. [PDF]

Biomedicines
Leonov DA, Mednova IA, Chernonosov AA.
europepmc   +1 more source

Plasma 3‐O‐Methyldopa Concentration Monitoring for Treatment Optimization in Foslevodopa/Foscarbidopa Infusion: Implications for Corrected Levodopa Availability: A Case Report

Movement Disorders Clinical Practice, EarlyView.
Shohei Okusa, Kotaro Okada, Yoshihiro Nihei, Risano Sakai, Takeshi Akiyoshi, Tomonori Nukariya, Jin Nakahara, Hisakazu Ohtani, Morinobu Seki   +8 more
wiley   +1 more source

Climate Shapes Elevational Gradients in Concentration, Composition, and Functional Diversity of Willow Metabolomes

Plant, Cell &Environment, EarlyView.
ABSTRACT Plants produce broad spectra of metabolites comprising primary metabolites involved in core physiological processes and specialized metabolites mediating responses to biotic and abiotic stress. Understanding how these various components of the metabolome respond to different environmental pressures can help us to understand drivers of ...
Sofian A. Renoult, Priscila Mezzomo, Jing V. Leong, Pavel Sebek, Shristee Panthee, Jaroslav Kukla, Petr Nguyen, Martin Moos, Dale L. Forrister, Natascha D. Wagner, Elvira Hörandl, Petr Koutecký, Brian E. Sedio, Jan Frouz, Nicole M. van Dam, Martin Volf   +15 more
wiley   +1 more source

Characterization of Novel Metabolites of the HIF Stabilizer JNJ-42041935 in Rats Using LC-HRMS for Doping Control Purposes: A Pilot Study. [PDF]

Drug Test Anal
Hou J, Yang S.
europepmc   +1 more source

Development of chalcones structure‐related to avobenzone: Photoprotection, photostability, and safety evaluation

Photochemistry and Photobiology, EarlyView.
Scaffold hopping strategy used to develop chalcones structure‐related to the avobenzone tautomer. Positive aspects of 2‐hydroxychalcones are highlighted. Abstract Chalcones are α,β‐unsaturated ketones with extended π‐conjugation, making them promising scaffolds for the development of organic UV filters.
Gabriela Zanella Marcon, Taíne de Bastos Brum, Nayara Fernanda Tokashike de Araujo, Gabriela Lascala Ramos, Bruna Cogo Borin, Ruth Barin, Aline Ferreira Ourique, André Passaglia Schuch, Andréa Inês Horn Adams, Lorena Rigo Gaspar Cordeiro, Letícia Cruz, Fernando Fumagalli   +11 more
wiley   +1 more source

Chemical Characterization of an Emerging Designer Steroid, 6-Bromo-androst-4-en-3,17-dione, via NMR and LC-HRMS and GC-HRMS. [PDF]

Drug Test Anal
He G, Zhu S, Liu X, Wang Z, Zhang L, Lu J, Li J.   +6 more
europepmc   +1 more source