Results 211 to 220 of about 60,310 (255)

Quantifying vitamin D and its metabolites by LC/Orbitrap MS

Analytical Methods, 2015
We developed a HPLC-HRMS method for the determination of 25(OH)D2, 25(OH)D3, epi-25(OH)D3, and vitamins D2and D3as well as 24,25(OH)2D3.
Reingard Raml, Maria Ratzer, Barbara Obermayer-Pietsch, Anton Mautner, Thomas R. Pieber, Frank M. Sinner, Christoph Magnes   +6 more
openaire   +1 more source

Analysis of trace phosphonates in authentic water samples by pre-methylation and LC-Orbitrap MS/MS

Water Research, 2019
Phosphonate is an important phosphorous species in the effluent of wastewater treatment plant (WWTP), contributing to eutrophication and interfering with phosphate removal in WWTP. It is particularly difficult to determine phosphonates in samples of complex solution chemistry, resulting in very limited information on their presence in environmental ...
Shu Wang, Shuhui Sun, Chao Shan, Bingcai Pan   +3 more
openaire   +2 more sources

Extraction optimization and screening of angiotensin-converting enzyme inhibitory peptides from Channa striatus through bioaffinity ultrafiltration coupled with LC-Orbitrap-MS/MS and molecular docking

Food Chemistry, 2021
Channa striatus is high-protein food with many health functions. This study aimed to prepare, screen and identify the angiotensin-converting enzyme inhibition peptides (ACEIPs) from C. striatus hydrolysates by response surface methodology and bioaffinity ultrafiltration coupled with LC-Orbitrap-MS/MS and molecular docking.
Tianxin, Ma, Qiaoqin, Fu, Qianggen, Mei, Zongcai, Tu, Lu, Zhang   +4 more
openaire   +2 more sources

Detection of a newFusariummasked mycotoxin in wheat grain by high-resolution LC–Orbitrap™ MS

Food Additives & Contaminants: Part A, 2011
A new Fusarium mycotoxin glucoside, fusarenon X-glucoside (FUXGlc), is reported for the first time in wheat grain that was artificially infected with Fusarium fungi. This new glucoside was identified using LC Orbitrap high-resolution mass spectrometry (LC-Orbitrap MS) analysis on the basis of accurate mass measurement of characteristic ions and MS/MS ...
H, Nakagawa, K, Ohmichi, S, Sakamoto, Y, Sago, M, Kushiro, H, Nagashima, M, Yoshida, T, Nakajima   +7 more
openaire   +2 more sources

Online LC‐Orbitrap MS method for the rapid molecular characterization of dissolved organic matter

Rapid Communications in Mass Spectrometry
Rationale High‐resolution mass spectrometry (HRMS) combined with electrospray ionization (ESI) has been the most useful technique for molecular characterization of dissolved organic matter (DOM) derived from diverse sources.
Yuguo Li, Chen He, Yahe Zhang, Quan Shi
openaire   +2 more sources

Study the influence of licorice and pomegranate drinks on nicotine metabolism in human urine by LC-orbitrap MS

Journal of Pharmaceutical and Biomedical Analysis, 2017
Nicotine-diet interactions have a particular importance on human health. Some food substances are subject to change hepatic CYP2A6 metabolism rate for nicotine and its levels in smokers consequently. This study investigates the effect of pomegranate and licorice drinks on nicotine metabolism, by a new developed and validated method for simultaneous ...
Ahmad Abu-awwad, Tawfiq Arafat, Oliver J. Schmitz   +2 more
openaire   +3 more sources

Chemical profiling and comparative analysis of different parts of Asarum heterotropoides using SPME-GC-QTOF-MS and LC- Orbitrap -MS

Journal of Pharmaceutical and Biomedical Analysis
Asari radix et rhizoma is the sole plant from the Aristolochiaceae family officially sanctioned for medicinal in China, primarily employed for treating colds and headaches, and is widely utilized in clinical practice. Initially, the entire plant was specified for medicinal use, but since 2005, the authorized part has been restricted to the roots and ...
Yun-Shu, Hu, Jian-Qing, Zhang, Meng, Xu, Huan-Ya, Yang, Chun-Xiang, Liu, Yun, Li, Qi-Rui, Bi, Yang, Yang, Qin-Hua, Chen, De-An, Guo   +9 more
openaire   +2 more sources

LC-Orbitrap MS analysis of the glycation modification effects of ovalbumin during freeze-drying with three reducing sugar additives

Food Chemistry, 2018
In general, the reducing sugars were extensively utilized as additives to prevent denaturation and inactivation during the freeze-drying process. However, different additives have unequal protective effects on the protein conformation. To evaluate the mechanism of protection the protein structure using different additives in the freeze-drying process ...
Yang Chen, Zong-cai Tu, Hui Wang, Guang-xian Liu, Zi-wei Liao, Lu Zhang   +5 more
openaire   +2 more sources

Comprehensive Metabolic Profiling of Resigratinib, a Novel FGFR Inhibitor, Using Integrated LC–MS/MS and LC‐Orbitrap‐HRMS

Rapid Communications in Mass Spectrometry
ABSTRACT Rationale Resigratinib, a potent fibroblast growth factor receptor (FGFR) inhibitor, is under clinical development for solid tumors such as cholangiocarcinoma. However, data on its hepatic metabolism remain limited.
Xiaoxia An, Yanting Mao, Ali Fan, Ting Ma   +3 more
openaire   +1 more source

Simultaneous determination of nicotine, cotinine, and nicotine N-oxide in human plasma, semen, and sperm by LC-Orbitrap MS

Analytical and Bioanalytical Chemistry, 2016
Nicotine (Nic) distribution in human fluids and tissues has a deleterious effect on human health. In addition to its poisoning profile, Nic may contribute to the particular impact of smoking on human reproduction. Although present in seminal fluid, still nobody knows whether nicotine is available in sperm or not.
Abu-Awwad, Ahmad, Arafat, Tawfiq, Schmitz, Oliver J.   +2 more
openaire   +2 more sources