Results 111 to 120 of about 4,803 (181)

Cinnamaldehyde From Cinnamon as a Food‐Derived Bioactive: Phytochemistry, Anticancer Mechanisms, Bioavailability, Nanoformulation and Safety

Food Frontiers, Volume 7, Issue 5, September 2026.
Cinnamaldehyde derived from Cinnamomum species exerts multitarget anticancer effects by promoting oxidative stress, mitochondrial dysfunction, apoptosis, cell‐cycle arrest, autophagy, and epigenetic changes, and by suppressing mitogen‐activated protein kinase (MAPK), phosphoinositide 3‐kinase/protein kinase B/mechanistic target of rapamycin (PI3K/Akt ...
Gervason Moriasi, Sally Kamau, Gulnaz Seitimova, Shynar Zhumagaliyeva, Javad Sharifi‐Rad, William N. Setzer, Daniela Calina   +6 more
wiley   +1 more source

Impact of Methylparaben on Cumulus Cell DNA Integrity and Porcine Oocyte Developmental Competence In Vitro

Journal of Applied Toxicology, Volume 46, Issue 9, Page 2985-2996, September 2026.
ABSTRACT Parabens (PBs) are compounds widely used as preservatives in personal care products, food, and pharmaceuticals. Methylparaben (MePB) is the most used by different industries due to its chemical properties and low cost. The high daily human exposure to these compounds has raised concerns about their potential effects on health, particularly on ...
Yenny Ramírez‐Jara, Brenda Casado, Miguel Betancourt, Adyeni Barajas‐Salinas, Eduardo Casas, Gabriela Hurtado‐Alvarado, Juan José Rodríguez‐Mercado, Alma López, Iván Bahena, Lizbeth Juárez‐Rojas, Leticia González‐Núñez, Fahiel Casillas   +11 more
wiley   +1 more source

A Perspective of Soy Isoflavones on Analytical, Biological, and Chemical Attributes

Legume Science, Volume 8, Issue 3, September 2026.
ABSTRACT This review covers key aspects of soybean (Glycine max), with a particular focus on its isoflavone content and biological properties. Soybeans maintain their position as both a nutraceutical and a pharmaceutical crop, with a broad range of dietary items used worldwide, including soy milk, fermented soy products, and various dietary supplements.
Sristy Suman, Joydeep Chatterjee, Gaurav Joshi, Raj Kumar, Muhammad Wahajuddin   +4 more
wiley   +1 more source

17‐epi‐Melianodiol, a new protolimonoid from Melia azedarach fruits, exhibits larvicidal activity and is associated with oxidative imbalance and midgut epithelial damage in Aedes aegypti larvae

Pest Management Science, Volume 82, Issue 9, Page 9240-9248, September 2026.
The bio‐guided phytochemical study resulted in the new compound 17‐epi‐melianodiol. The compound eliminated 100% of Aedes aegypti larvae at 100 ppm, causing pronounced morphological changes, cuticular damage, and extensive vacuolization. Abstract BACKGROUND In Brazil, Aedes aegypti is the primary vector of arboviruses such as dengue, chikungunya ...
Kethleen Duarte Crespo Soares, Thalya Soares Ribeiro Nogueira, Maria Aparecida Aride Bertonceli, Renata Rodrigues da Silva Robaina, Leticia Oliveira da Rocha, Francisco José Alves Lemos, Kátia Valevski Sales Fernandes, Raimundo Braz‐Filho, Ivo José Curcino Vieira   +8 more
wiley   +1 more source

Sustainable Polymer Biocomposites for Food Packaging: Green Nanotechnology, Circular Plastic Upcycling and Smart Functional Materials

Packaging Technology and Science, Volume 39, Issue 9, Page 1141-1178, September 2026.
Graphical abstract showing the development of biodegradable polymer biocomposites reinforced with natural fibres, green nanoparticles and waste‐plastic upcycling pathways toward sustainable smart food packaging materials ABSTRACT The fundamental hypothesis behind this review is that the combination of biodegradable polymer‐based biocomposites, which ...
Chandra Sekhar Espenti, Jaewoong Lee
wiley   +1 more source

Nanotechnology‐Based Immunostimulants in Aquaculture: Mechanisms, Advances and Practical Applications

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Nano‐immunostimulants improve fish health through targeted and controlled delivery of immunostimulatory compounds. Biodegradable polymeric and lipid‐based nanocarriers enhance immune responses, bioavailability and disease resistance while reducing antibiotic dependence and environmental impact.
Mustafa Öz, Enes Üstüner
wiley   +1 more source

Pyridyl‐Thiazole‐Thiosemicarbazones as Antitrypanosomatidae Agents: Design, Synthesis, and In Silico Profiling

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
A novel pyridine–thiazole derivative, Compound 8, exhibited potent dual antitrypanosomatid activity. It demonstrated remarkable in vitro efficacy against Trypanosoma cruzi (IC50 = 1.0 µM) and L. amazonensis (IC50 = 3.9 µM). Molecular docking studies suggested interactions with heme and multiple molecular targets.
Anderson José Firmino Santos da Silva, Daiane Santiago da Cruz Olimpio, Lucas Manoel da Silva Sousa, Graziella Leite Brondani, Tacylla Lima Silva, Wéllyda Belmira de Lira Silva, Natáli Tereza Capistrano Costa, Marcelo Zaldini Hernandes, Policarpo Ademar Sales Junior, Valéria Rêgo Alves Pereira, Ana Cristina Lima Leite   +10 more
wiley   +1 more source

Actinomycin Derivatives: Structural Diversification and Biological Activities

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Actinomycins are chromopeptide antibiotics exhibiting remarkable structural diversity and broad bioactivity. This review traces their development from naturally occurring D‐, X‐, A‐, G‐, Y‐, and Z‐type analogs to precursor‐directed, synthetic, and semisynthetic derivatives.
Özge Can, Erdal Bedir
wiley   +1 more source

Valorization of Ficus carica Pruning Residues as Selective Botanical Insecticides: Optimized Furanocoumarin Extraction, Efficacy Against Neotropical Stink Bugs, and Mechanistic Insights via Molecular Docking

Archives of Insect Biochemistry and Physiology, Volume 122, Issue 4, August 2026.
Optimized extracts from Ficus carica pruning waste exhibit strong biological activity against major stink bug pests. Complementary in silico analyses suggest this efficacy relies on pest‐specific acetylcholinesterase inhibition, predicting a promising, pollinator‐safe alternative for sustainable agriculture.
Thais A. Almeida, Arley R. Páez, Lara T. M. Costa, Guy Smagghe, Yara M. Cardoso, Letícia M. Faria, Eugênio E. Oliveira, João Paulo V. Leite   +7 more
wiley   +1 more source

Lippia umbellata Cav.: Chemical Composition, Insecticidal, and Antimicrobial Activities

Chemistry &Biodiversity, Volume 23, Issue 8, August 2026.
Hexane extracts of Lippia umbellata leaves and flowers contain lupenone, α‐amyrin, and hentriacontane. They exhibit insecticidal activity against Drosophila melanogaster and inhibit AChE in vitro and in silico. Furthermore, the extracts can inhibit the growth of medically important bacteria and yeasts, including multidrug‐resistant strains.
José Guillermo Avila‐Acevedo, Miriam Arlette López‐Pérez, Ana Karen Villagómez‐Guzmán, Edgar Antonio Estrella‐Parra, Nallely Álvarez‐Santos, Israel Valencia‐Quiroz, Julieta Orozco‐Martínez, Ma. Edith López‐Villafranco, Silvia Aguilar‐Rodríguez, Carlos Leonardo Céspedes‐Acuña, Juio Alarcón‐Enos, Ana María García‐Bores   +11 more
wiley   +1 more source