Results 171 to 180 of about 45,100 (264)

Peptide‐Enabled Nanoplatforms for Malaria and Leishmaniasis: From Intracellular Targeting to Translational Diagnostic Perspectives

open access: yesChemMedChem, Volume 21, Issue 18, 28 September 2026.
Peptide‐enabled nanoplatforms offer multifunctional strategies for the treatment and diagnosis of malaria and leishmaniasis. Liposomal, polymeric, and metallic nanocarriers, together with cell‐penetrating peptides and parasite‐derived mimotopes, can improve targeted drug delivery, stability, bioavailability, and intracellular localization.
Christian S. Carnero Canales   +7 more
wiley   +1 more source

Beyond the Active Site: First‐In‐Class Leishmania Infantum Trypanothione Reductase Dimerization Disruptors as Antileishmanial Leads

open access: yesChemMedChem, Volume 21, Issue 18, 28 September 2026.
This review outlines a pioneering strategy to inhibit Leishmania infantum trypanothione reductase by disrupting its dimer interface. From peptides to small‐molecule proteomimetics, multiple chemotypes achieved potent enzymatic inhibition and notable cellular antileishmanial activity, highlighting a new therapeutic paradigm.
María‐José Camarasa   +3 more
wiley   +1 more source

Cytotoxicity, antibacterial efficacy, and fluoride content of commercial herbal toothpastes. [PDF]

open access: yesBDJ Open
Poeaim N   +7 more
europepmc   +1 more source

Physicochemical Characterization and Larvicidal Activity of a Rutin-Zn Material against <i>Aedes aegypti</i>. [PDF]

open access: yesACS Omega
Santos DS   +10 more
europepmc   +1 more source

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