Direct infection of dendritic cells during chronic viral infection suppresses antiviral T cell proliferation and induces IL-10 expression in CD4 T cells. [PDF]
PLoS ONE, 2014 Elevated levels of systemic IL-10 have been associated with several chronic viral infections, including HCV, EBV, HCMV and LCMV. In the chronic LCMV infection model, both elevated IL-10 and enhanced infection of dendritic cells (DCs) are important for ...
Carmen Baca Jones +5 more
doaj +1 more source
Blockade but not overexpression of the junctional adhesion molecule C influences virus-induced type 1 diabetes in mice [PDF]
, 2013 Type 1 diabetes (T1D) results from the autoimmune destruction of insulin-producing beta-cells in the pancreas. Recruitment of inflammatory cells is prerequisite to beta-cell-injury.
Aurrand-Lions, Michel +10 more
core +3 more sources
Reemergence of Lymphocytic Choriomeningitis Mammarenavirus, Germany
Emerging Infectious Diseases, 2023 Lymphocytic choriomeningitis mammarenavirus (LCMV) is a globally distributed zoonotic pathogen transmitted by house mice (Mus musculus). We report the reemergence of LCMV (lineages I and II) in wild house mice (Mus musculus domesticus) and LCMV lineage ...
Calvin Mehl +10 more
doaj +1 more source
Fast LCMV-Based Methods for Fundamental Frequency Estimation [PDF]
IEEE Transactions on Signal Processing, 2013 Recently, optimal linearly constrained minimum variance (LCMV) filtering methods have been applied to fundamental frequency estimation. Such estimators often yield preferable performance but suffer from being computationally cumbersome as the resulting cost functions are multimodal with narrow peaks and require matrix inversions for each point in the ...
Jensen, Jesper Rindom +4 more
openaire +4 more sources
Constant-Beamwidth LCMV Beamformer with Rectangular Arrays
Algorithms, 2023 This paper presents a novel approach utilizing uniform rectangular arrays to design a constant-beamwidth (CB) linearly constrained minimum variance (LCMV) beamformer, which also improves white noise gain and directivity. By employing a generalization of the convolutional Kronecker product beamforming technique, we decompose a physical array into ...
Vitor Probst Curtarelli, Israel Cohen
openaire +2 more sources
Congenitally acquired persistent lymphocytic choriomeningitis viral infection reduces neuronal progenitor pools in the adult hippocampus and subventricular zone. [PDF]
PLoS ONE, 2014 Lymphocytic choriomeningitis virus (LCMV) can be transmitted through congenital infection, leading to persistent infection of numerous organ systems including the central nervous system (CNS).
Tony Sun, Michael J Vasek, Robyn S Klein
doaj +1 more source
Chronic viral infection promotes sustained Th1-derived immunoregulatory IL-10 via BLIMP-1 [PDF]
, 2014 During the course of many chronic viral infections, the antiviral T cell response becomes attenuated through a process that is regulated in part by the host. While elevated expression of the immunosuppressive cytokine IL-10 is involved in the suppression
Brüstle, Anne +12 more
core +1 more source
Virology Journal, 2023 Background Increased glucose uptake and utilization via aerobic glycolysis are among the most prominent hallmarks of tumor cell metabolism. Accumulating evidence suggests that similar metabolic changes are also triggered in many virus-infected cells ...
Lucia Baďurová +5 more
doaj +1 more source
Mouse-to-Human Transmission of Variant Lymphocytic Choriomeningitis Virus
Emerging Infectious Diseases, 2007 A case of lymphocytic choriomeningitis virus (LCMV) infection led to investigation of the reservoir. LCMV was detected in mice trapped at the patient's home, and 12 isolates were recovered.
Sébastien Emonet +4 more
doaj +1 more source
mBio, 2022 Lymphocytic choriomeningitis virus (LCMV) is a well-studied mammarenavirus that can be fatal in congenital infections. However, our understanding of LCMV and its interactions with human host factors remains incomplete.
Jamin Liu +7 more
doaj +1 more source