Results 71 to 80 of about 6,793 (233)

Primary large cell neuroendocrine carcinoma of the distal ureter: A rare entity

Human Pathology: Case Reports, 2021
Large cell neuroendocrine carcinoma (LCNEC) of the ureter is an extremely rare entity. Herein, we present a case of primary LCNEC of the distal ureter in an 80-year-old male with a history of intermittent hematuria and a mass in the right distal ureter ...
Harpreet Kaur Rai, George Goucher, Jehonathan H. Pinthus, Phillip Williams   +3 more
doaj   +1 more source

A Retrospective Study on the Clinicopathological Characteristics and Prognostic Analysis of Gynecologic Neuroendocrine Carcinoma

Cancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Gynecologic neuroendocrine carcinomas (NECs) are rare, highly aggressive malignancies with early metastatic potential and limited evidence to guide optimal management across different primary sites. Aims To characterize the clinicopathological features, treatment patterns, survival outcomes, and prognostic factors of gynecologic ...
Yedan Ren, Sen Li, Simin Xiang, Junfen Xu   +3 more
wiley   +1 more source

Large-cell neuroendocrine carcinoma of the gynecologic tract: Prevalence, survival outcomes, and associated factors

Frontiers in Oncology, 2022
BackgroundWe aimed to assess the clinical behavior of gynecologic large-cell neuroendocrine carcinoma (LCNEC) via a retrospective analysis of data from 469 patients.MethodsPatients diagnosed with gynecologic LCNEC from 1988 to 2015 were identified using ...
Li Pang, Jie Chen, Xiaohan Chang
doaj   +1 more source

Molecular heterogeneity of non-small cell lung carcinoma patient-derived xenografts closely reflect their primary tumors [PDF]

, 2017
Availability of lung cancer models that closely mimic human tumors remains a significant gap in cancer research, as tumor cell lines and mouse models may not recapitulate the spectrum of lung cancer heterogeneity seen in patients. We aimed to establish a
Balbin, Barretina, Cancer Genome Atlas Research N, Cancer Genome Atlas Research N., Chen, Chen, Conway, Cox, Cox, Daniel, Deeb, Domcke, Drake, Eirew, El-Maraghi, Fichtner, Forbes, Gandara, Gao, Garnett, Gazdar, Gillet, Hao, Herrmann, Ikebuchi, Ilie, Imielinski, John, Johnson, Lee, Li, Loo, Malaney, Mattern, Mishra, Mo, Pardoll, Rikova, Rodriguez, Sanders, Saunders, Sharma, Singh, Stewart, Tong, Trejo, Williams, Zhang, Zhu   +48 more
core   +1 more source

Combined Large Cell Neuroendocrine Carcinomas of the Lung: Integrative Molecular Analysis Identifies Subtypes with Potential Therapeutic Implications [PDF]

, 2022
Simple Summary In this manuscript, we offer an integrated molecular analysis of 44 combined large cell neuroendocrine carcinomas (CoLCNECs) in order to deepen the knowledge about these rare histotypes and to clarify their relationship with lung cancers ...
Benvenuti M. R., Bercich L., Berruti A., Bossi P., Bria E., Capella C., Cattaneo L., Centonze G., Ciaparrone C., Del Gobbo A., Fabbri A., Ferrero S., Filugelli M., Garzone G., Giudice L., Giugno R., Gkountakos A., Grillo F., Infante M., Maisonneuve P., Mangogna A., Mastracci L., Milella M., Milione M., Monti V., Pastorino U., Pilotto S., Prinzi N., Pusceddu S., Rolli L., Sabella G., Scarpa A., Simbolo M., Spaggiari P., Testi A.   +34 more
core   +1 more source

Primary Lung Carcinoma with a Component of Large Cell Neuroendocrine Carcinoma (LCNEC)

Haigan, 2008
目的．大細胞神経内分泌癌は臨床病理学的に新たに確立されたまれな腫瘍であるが，その組織像は均一でないことがある．この研究の目的は，当院で経験した大細胞神経内分泌癌の成分を含んだ混合型大細胞神経内分泌癌もしくは混合型小細胞癌の臨床病理学的特徴を解明することである．対象．2003年4月から2008年3月までの間に，大細胞神経内分泌癌の成分を含んだ混合型大細胞神経内分泌癌もしくは混合型小細胞癌と診断された4例を対象とした．結果．性別は全例男性であり，年齢は65～85歳で平均76.8歳であった．術前のpositron emission tomography（PET）with 18F-fluorodeoxyglucose（FDG）検査では全例腫瘍に高度な集積が認められた．術式は区域切除が1例，肺葉切除が3例で ...
Ryo Maeda, Noritaka Isowa, Yuji Kawasaki, Hirokazu Tokuyasu, Hirokazu Touge   +4 more
openaire   +2 more sources

Treatment‐related changes in the prostate: past, present and future therapies

Histopathology, Volume 88, Issue 1, Page 40-52, January 2026.
Radiation therapy alters tumour morphology and immunoprofile in prostate cancer. Residual carcinoma shows distorted glandular architecture on H&E and loss of basal markers with preserved AMACR expression by immunohistochemistry, aiding in the recognition of treatment effect in prostate biopsies.
Katrina Collins, Liang Cheng
wiley   +1 more source

神経内分泌系腫瘍におけるロゼット構造の形態学的検討とその病理診断への応用 [PDF]

, 2012
筑波大学University of Tsukuba博士（医学）Doctor of Philosophy in Medical Sciences2011【要旨 ...
96386, 里見, 介史
core   +1 more source

The association between XPC Lys939Gln gene polymorphism and urinary bladder cancer susceptibility: a systematic review and meta-analysis [PDF]

, 2013
BACKGROUND: Numerous epidemiological studies have been conducted to explore the association between the Lys939Gln polymorphism of Xeroderma pigmentosum group C (XPC) gene and urinary bladder cancer susceptibility. However, the results remain inconclusive.
Kun Dou, Qingzhu Xu, Xiaolu Han
core   +1 more source

Bone metastases from neuroendocrine neoplasms: Results of an Italian nationwide survey of natural history and management

Journal of Neuroendocrinology, Volume 38, Issue 1, January 2026.
Abstract Bone metastases (BMs) were reported in <15% of cases of neuroendocrine neoplasms (NENs). Their clinical behavior is various and clinical management is still undefined. This study aimed to describe the clinical practical management and survival outcome of neuroendocrine neoplasm patients with BMs.
Nicola Fazio, Patrick Maisonneuve, Anna Maria Frezza, Nicoletta Ranallo, Toni Ibrahim, Anna La Salvia, Maria Pia Brizzi, Chiara De Divitiis, Salvatore Tafuto, Sara Pusceddu, Riccardo Marconcini, Mauro Cives, Cristina Ferrari, Davide Campana, Delia De Lisi, Daniele Santini, Antongiulio Faggiano, Roberta Modica, Sara Massironi, Antonio Bianchi, Francesco Panzuto, Lorenzo Antonuzzo, Elisa Pellegrini, Vito Amoroso, Ivana Puliafito, Elettra Merola, Nicola Silvestris, Chiara Maria Grana, Francesca Spada   +28 more
wiley   +1 more source