Results 181 to 190 of about 61,903 (248)

Apiol-Rich and Caryophyllene-Oxygenated Essential Oils from Amazonian <i>Piper</i> Species as Dual-Action Biopesticides: Broad-Spectrum and Selective Antifeedant. [PDF]

Molecules
Ruiz-Vásquez L, Andrés Yeves MF, Vela Mendoza MDJ, Ruiz Mesia L, Ruiz Mesia W, Ricopa Cotrina H, Tapia D, Valcarcel F, Gonzalez-Coloma A.   +8 more
europepmc   +1 more source

Unraveling the Anti‐Arthritic Potential of Bioactive Compounds From Melaleuca alternifolia Oil: Integrated In Vivo, Molecular Docking, and Network Pharmacology Insights

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
Melaleuca alternifolia oil demonstrated significant anti‐arthritic effects in CFA‐induced rats by reducing paw edema, PGE2 levels, and inflammatory biomarkers. It improved hematological and histopathological parameters, modulated cytokine expression, and showed promising phytochemical‐target interactions through GC–MS, network pharmacology, and ...
Sana Sabir, Aisha Mobashar, Hossam Kamli, Hafiza Mahnoor Baghdadi, Bushra Akhtar, Amir Ali, Sana Saleem, Khalid Hussain, Kiran Mashaal, Esmael M. Alyami, Mona Alsolami, Fakhreldeen Dabiellil, Pravin Badhe, Gehan M. Elossaily, Muhammad Shahab, Abdel‐Rhman Z. Gaafar   +15 more
wiley   +1 more source

Genetic heterogeneity and pathogenic potential of historical Crimean-Congo hemorrhagic fever virus isolates in China. [PDF]

Virol Sin
Moming A, Bai Y, Zhu Q, Jin J, Fang Y, Huang S, Wu Q, Su Z, Zhao G, Tang S, Wang M, Hu Z, Zhang Y, Deng F, Shen S.   +14 more
europepmc   +1 more source

FAM107A loss facilitates TTK‐OPTN‐mediated mitophagy to drive docetaxel resistance in castration‐resistant prostate cancer

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
In the progression of docetaxel resistance, downregulation of FAM107A releases its transcriptional repression of TTK, leading to TTK upregulation. TTK enhances the interaction and phosphorylation of OPTN. This activates mitophagy in tumor cells, facilitates clearance of damaged mitochondria, reduces intracellular reactive oxygen species accumulation ...
Yishan Zhang, Fan Zou, Mingdong Wang, Chenyue Wu, Yingwei Xie, Yongjun Quan, Wei Yan, Yupeng Zheng, Lianhua Li, Yuexin Liu, Jian Yu, Hao Ping   +11 more
wiley   +1 more source

Phytochemical Profile and Bioactive Potential of <i>Erythroxylum nummularium</i> Peyr: Evaluation of Antioxidant, Antimicrobial, and Antinociceptive Properties. [PDF]

Antioxidants (Basel)
da Silva NS, Amorim ÍTC, de Souza FM, Lima BO, Dos Santos TC, de Oliveira DM, Marques LM, Cruz MP, de Carvalho AL, Yatsuda R, Moreira BO.   +10 more
europepmc   +1 more source

Quinoline and Phthalimide Substituted Silicon Phthalocyanines as Multi‐Target Inhibitors of Cholinesterases and Carbonic Anhydrases

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Two novel axially substituted silicon phthalocyanines were synthesized and characterized. Compound 2a exhibited significantly enhanced inhibition of AChE, BChE, hCA I and hCA II, supported by molecular docking and SAR analysis, highlighting its potential as a multifunctional enzyme inhibitor with promising biological activity.
Seda Ünlü, Zeynep Köksal, Kevser Kübra Kırboğa, Fikriye Tuncel Elmalı   +3 more
wiley   +1 more source

Fisetin Attenuates Uterine Leiomyoma in Rats: Potential Crosstalk Between HMGB1, SphK1/S1P, and TGF‐β Signaling

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Fisetin attenuates monosodium glutamate‐induced uterine leiomyoma by reducing sex hormones and suppressing S1P/SphK1 signaling, HMGB1‐mediated inflammation, and fibrotic markers. These coordinated effects alleviate fibrosis and restore uterine tissue architecture, highlighting fisetin as a promising natural therapeutic candidate.
Nashwa Maghraby, Esraa Khalaf, Marwa T. Hussien, Ahmed M. A. Sobh, Nagla T. Elmelegy   +4 more
wiley   +1 more source

Paralysis efficiency (PD₅₀) scales linearly with lethality (LD₅₀) in spider venoms. [PDF]

Toxicon X
Lyons K, Leonard D, McSharry L, Martindale M, Collier BL, Vitkauskaite A, Dunbar JP, Dugon MM, Healy K.   +8 more
europepmc   +1 more source

Next‐Generation Pluronic Micelles for Advanced Drug Delivery Application

Macromolecular Materials and Engineering, Volume 311, Issue 9, September 2026.
The present review provides a comprehensive overview of Pluronic‐based micelles for advanced drug and gene delivery. It highlights their structure, classification, synthesis, self‐assembly, and functionalization, as well as their biocompatibility and stimuli‐responsive properties.
Manoj Gundeti, Nithin Vidiyala, Shreya Dalvi, Rushikesh Girase, Sunil kumar Thota, Keshav Raj Paudel, Sathish Dyawanapelly   +6 more
wiley   +1 more source

Imidazopyridine derivatives as promising anti-<i>Toxoplasma gondii</i> agents: <i>in vitro</i> studies, <i>in vivo</i> testing, and molecular modeling analysis. [PDF]

RSC Adv
Sabt A, Okasha H, Farag H, Fahmy ZH, Selim EAH, Ibrahim HAA, Thabit MG, Radwan AF, Eldehna WM, R Mostafa R.   +9 more
europepmc   +1 more source