Results 191 to 200 of about 61,903 (248)

Abscopal Effect in Radiation Therapy: The Immune Mechanisms and Clinical Advances

MedComm, Volume 7, Issue 9, September 2026.
The schematic outlines the key events of the abscopal effect. (Ignition) Local radiotherapy (RT) induces the release of immunogenic signals from the tumor, leading to dendritic cell (DC) activation. (Orchestration) In the tumor‐draining lymph node (TDLN), DCs prime naive T cells into cytotoxic T lymphocytes (CTLs), a process modulated by regulatory T ...
Yihong Dong, Moran Chen, Xupeng Hou, Xiaoya Tang, Xiaoli Yu, Jing Liu   +5 more
wiley   +1 more source

Summary of the Safety Assessment Data of the Most Common Organogermanium Food Ingredient, Asaigermanium (Poly-trans-[(2-carboxyethyl)germasesquioxane]). [PDF]

J Food Sci
Doiyama S, Nakamura T.
europepmc   +1 more source

Cyclodextrin‐Based Supramolecular Complex Modulates the Bioaccessibility and Vascular Activity of Plinia peruviana Extract

ChemistryOpen, Volume 15, Issue 9, September 2026.
Cyclodextrin complexation improved the delivery of plant polyphenols by increasing intestinal bioaccessibility while preserving vascular activity and maintaining low oral toxicity. This strategy highlights the potential of supramolecular systems to enhance the therapeutic value of natural products for cardiovascular health.
Priscila L. Paula, Nubia B. Andrade, Matheus T. Branca, Lucas de Araújo Carvalho, Bruno A. de Oliveira, Adilson D. da Silva, Angela C. Resende, Lara M. Campos, José Maria Barbosa‐Filho, Luiz Fernando C. Oliveira, Vinícius N. Rocha, Ângelo Márcio L. Denadai, Rodrigo L. Fabri   +12 more
wiley   +1 more source

Environmental and sustainable valorization of spent adsorbent: safety and acute toxicity evaluation in rats via probit analysis. [PDF]

Sci Rep
Aita SA, Mahmoud R, El-Ela FIA, Arafa EG, Zaher A.   +4 more
europepmc   +1 more source

Integrative Phytochemical, Antioxidant, and NLRP3‐Linked and Anti‐Inflammatory Evaluation of Salvia balansae (Aurès Chemotype): Insights Into Its Safety and Therapeutic Potential

ChemistryOpen, Volume 15, Issue 9, September 2026.
An endemic Aurès chemotype of Salvia balansae emerges as a rich source of luteolin, rosmarinic acid, and other polyphenols with potent antioxidant and NLRP3‐linked anti‐inflammatory activities. Protection against experimental inflammation, favorable enzyme‐modulating properties, and a wide safety margin highlight its promise as a pharmaceutical and ...
Khadra Afaf Bendrihem, Messaoud Hachemi, Mohamed Aimene Mihoubi, Fares Mohamed Amine, Majid Sharifi‐Rad, Dalal Houhou, Rahma Guemmaz, Khaled Kherraz, Azzeddine Zeraib, Assia Abdelmalek, Aicha Mouane, Nour Elhouda Ayeb, Chawki Bensuici, Maria Chikha, Kamel Nagaz, Ayomide Victor Atoki, Mohammed Messaoudi   +16 more
wiley   +1 more source

Acute toxicity and sex-dependent lethality of isotonitazene in fischer 344 rats. [PDF]

Front Toxicol
Hernandez YL, Vinerean H, Aggarwal S.
europepmc   +1 more source

Integrated In Silico Discovery of Thymoquinone Analogs Targeting the Keap1–Nrf2 Pathway for Amyotrophic Lateral Sclerosis Therapy

ChemistryOpen, Volume 15, Issue 9, September 2026.
Integrated in silico discovery of thymoquinone analogs as potent Keap1 inhibitors for ALS therapy. Using validated QSAR, docking, and 200 ns MD simulations, we identified brain‐penetrant leads (CHEMBL3416163, CHEMBL4636830, and CHEMBL221598) with binding affinities up to fourfold stronger than thymoquinone, offering a targeted strategy to restore redox
Jabir C. Nalicho, Petro E. Mabeyo, Andrew S. Paluch, Lucas Paul   +3 more
wiley   +1 more source

Efficacy and limitations of ultraviolet-C light for control of Lygus hesperus (Hemiptera: Miridae) eggs and nymphs in strawberry. [PDF]

J Econ Entomol
Koubek CT, Aghaee MA.
europepmc   +1 more source

Synthesis of Sulfonamides in the Biobased Solvent Cyrene

ChemistryOpen, Volume 15, Issue 9, September 2026.
An alternative and efficient protocol for sulfonamide synthesis using the biobased solvent Cyrene is reported. A broad range of amines reacts smoothly with sulfonyl chlorides at room temperature, furnishing 20 sulfonamides in moderate to high yields within 30–60 min. Products are isolated by simple precipitation without chromatography, while Cyrene can
Michela Galli, Andrea Fulminante, Alessandro Fiori, Valerio Fasano, Alessandra Silvani, Daniele Passarella, Andrea Citarella   +6 more
wiley   +1 more source

Stage-Dependent Embryolethality of Diclofenac Sodium: Quantitative Assessment of Dose-Time Interaction and Critical Windows of Susceptibility in the In Ovo Chicken Embryo Model. [PDF]

Vet Sci
Kizilay H, Rama ST.
europepmc   +1 more source