Results 51 to 60 of about 44,701 (203)

Modeling Supports Combinatorial Effects Between Pharmacological and Non‐Pharmacological Interventions to Prevent Opioid‐Induced Cardiac Arrest

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Few studies have quantified the effects of non‐pharmacological interventions (e.g., rescue breathing) in the setting of community opioid overdose. We extended a previously validated model for opioid antagonists by incorporating the mechanism of rescue breathing, and quantified combinatorial effects between rescue breathing and various formulations of ...
Bradlee Thrasher   +12 more
wiley   +1 more source

Determination of Total Levels of Secondary Metabolites and Oral Acute Toxicity Testing of Purple Leaf Ethanol Extract (PLEE) in Wistar Rats

open access: yesJournal of Public Health and Pharmacy
Introduction: The use of traditional medicines derived from the active ingredients of several types of plants is preferred by the community in treating several types of diseases. One of the plants that has been used by the community as medicine is purple
Niluh Puspita Dewi   +4 more
doaj   +1 more source

Estimation of LD50 by moving averages [PDF]

open access: yesJournal of Hygiene, 1952
Methods of graduation of a series of observations by means of moving averages were discussed by Sheppard (1914), and subsequently by Sherriff (1920) and a number of other writers. These methods based on least squares or weighted least squares solutions differ from actuarial or summation methods.
openaire   +2 more sources

Fe‐Free Photocatalysis‐Self‐Fenton System for Ultraefficient Water Purification Enabled by Carbon Nitride With Strong Built‐in Electric Field

open access: yesEcoEnergy, EarlyView.
This study reports a photocatalytic H₂O₂ production rate of 14.9 mmol g⁻¹ h⁻¹, representing a 22.2‐fold enhancement. Additionally, the Fe‐free PSFs achieved complete degradation of 100 mg·L⁻¹ tetracycline within 10 min across a wide pH range. ABSTRACT Photocatalytic‐self‐Fenton system (PSFs) hold great promise for water purification through in situ ...
Yuhan Yan   +6 more
wiley   +1 more source

Uji Toksisitas Akut Dermal Gel Antioksidan Topikal C-4-Hidroksi-3-Metoksifenilkaliks[4] Resorsinarena Secara In Vivo Pada Tikus Wistar

open access: yesJurnal Penelitian Pendidikan, Psikologi dan Kesehatan
Pemberian antioksidan topikal merupakan cara yang efektif untuk melindungi kerusakan kulit yang disebabkan oleh sinar ultraviolet. Senyawa C-4-hidroksi-3-metoksifenilkaliks[4]-resorcinarene telah diteliti aktivitas antioksidannya, tabir surya, dan ...
Wade Marlinda   +2 more
doaj   +1 more source

Acute oral toxicity evaluation of Hridayarnava Rasa (A Herbo-Mineral Ayurvedic Formulation) prepared from aśodhita and śodhita tāmra bhasma

open access: yesAncient Science of Life, 2018
Background: Herbo-mineral preparations used in Ayurveda are seen as a matter of concern nowadays; especially for containing metals such as mercury, lead, and copper.
Chandrashekhar Yuvaraj Jagtap   +3 more
doaj   +1 more source

An algorithm for seizure detection in rodents

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Epilepsy animal research often relies on long‐term intracranial electroencephalographic (iEEG) recordings. Here, we describe an artificial neural network (ANN) algorithm for automatic detection of seizures. Methods The algorithm was trained on iEEG recordings of three mouse models of chronic epilepsy: (1) the pilocarpine model of ...
Lyna Kamintsky   +9 more
wiley   +1 more source

Harnessing Free Radical Scavenging Potential of Caffeic Acid as a Nutraceutical—A Review

open access: yesFood Safety and Health, EarlyView.
Caffeic acid has emerged as a promising bioactive molecule with multiple pharmacological properties, including antioxidant, antimicrobial, anti‐inflammatory, organ protective properties and metal‐chelating ability. This review emphasizes the dietary sources, structural characteristic, molecular mechanism underlying health promoting effects of caffeic ...
Pavitra Behra   +2 more
wiley   +1 more source

Acute toxicity of antiparasitic selamectin-based drug

open access: yesРоссийский паразитологический журнал
The purpose of the research is to evaluate some toxicological parameters of antiparasitic selamectin-based drug.Materials and methods. The study drug is a solution for external use, 1 mL of which contains the active component selamectin (120 mg), as well
D. V. Kadyrova
doaj   +1 more source

Biocontrol of the pine processionary moth Thaumetopoea pityocampa (Denis and Schiffermuller, 1775) with plant extracts

open access: yesArxius de Miscel-lània Zoològica, 2019
Control biològic de la papallona de la processionària del pi Thaumetopoea pityocampa (Denis i Schiffermuller, 1775) mitjançant diversos extractes vegetals La finalitat del present estudi és oferir alternatives amb bioinsecticides elaborats a partir de
M. Kherroubi,   +3 more
doaj   +1 more source

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