Results 91 to 100 of about 750,498 (385)
Proof That Lower Is Better--LDL Cholesterol and IMPROVE-IT.
New England Journal of Medicine, 2015 The so-called LDL hypothesis is the concept that excess low-density lipoprotein (LDL) cholesterol is a causal factor in the development of atherosclerotic vascular disease.
J. Jarcho, J. Keaney
semanticscholar +1 more source
, 2016 Although multi-label learning can deal with many problems with label ambiguity, it does not fit some real applications well where the overall distribution of the importance of the labels matters.
Geng, Xin
core +1 more source
Advanced Materials, EarlyView.This work has developed a dual enzyme‐mimicking and ultrasound‐responsive Nb2C‐Pt@HA‐PEG nanozyme. ROS‐eliminating and antiinflammatory capability of Nb2C‐Pt@HA‐PEG under US irradiation are demonstrated on macrophages and endothelial cells in vitro. Nb2C‐Pt@HA‐PEG‐mediated sonocatalytic therapy exerts an outstanding anti‐atherosclerosis efficacy by ...
Qianqian Bai +6 more
wiley +1 more source
Molecular genetics of the LDL receptor gene in familial hypercholesterolemia
Human Mutation, 1992 The low density lipoprotein (LDL) receptor is a cell surface transmembrane protein that mediates the uptake and lysosomal degradation of plasma LDL, thereby providing cholesterol to cells.
H. Hobbs, Michael S. Brown, J. Goldstein
semanticscholar +1 more source
Structural Properties of High and Low Density Water in a Supercooled Aqueous Solution of Salt
, 2011 We consider and compare the structural properties of bulk TIP4P water and of a sodium chloride aqueous solution in TIP4P water with concentration c = 0.67 mol/kg, in the metastable supercooled region. In a previous paper [D. Corradini, M.
Corradini, D., Gallo, P., Rovere, M.
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Increased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with type 2 diabetes and effect of metformin [PDF]
, 2010 OBJECTIVE The aim of this study was to investigate whether apolipoprotein B100 of LDL suffers increased damage by glycation, oxidation, and nitration in patients with type 2 diabetes, including patients receiving metformin therapy.
A. Ceriello +25 more
core +3 more sources
Advanced Materials, EarlyView.The artesunate nanoplatform selectively targets ECM CAF, functioning as a GTPase inhibitor through disruption of intracellular serine homeostasis. This metabolic intervention effectively suppresses MAPK cascade activity, which consequently inhibits PTT‐induced CAF to ECM CAF differentiation.
Dongdong Zheng +19 more
wiley +1 more source
A correlative study of uric acid with lipid profile
Asian Journal of Medical Sciences, 2013 Objective: the study was conducted to verify the association of hyperuricemia with lipid profile in a group of Assamese people so as to take necessary precautions from developing future cardiovascular disease (CVD).
Devajit Sarmah
doaj +1 more source
Lipoprotein lipase-facilitated uptake of LDL is mediated by the LDL receptor [PDF]
Journal of Lipid Research, 2007 LPL mediates the uptake of lipoproteins into different cell types independent of its catalytic activity. The mechanism of this process and its physiological relevance are not clear. Taking into account the importance of the endothelial barrier for lipoprotein uptake, in vitro studies with primary aortic endothelial cells from wild-type and low density ...
Martin Merkel +6 more
openaire +3 more sources
EFEKTIVITAS KOMBINASI DL-αTOKOFEROL DAN ASAM ASKORBAT TERHADAP KADAR LDL-OX, sCD36, sVCAM-1 DAN NO PADA ANAK SINDROM NEFROTIK [PDF]
, 2015 Latar Belakang: Stres oksidatif, disfungsi endotel dan inflamasi mendasari proses aterosklerosis pada anak sindrom nefrotik (SN). Kombinasi dl-α-tokoferol dan asam askorbat berpotensi menurunkan proses stress oksidatif dan disfungsi endotel banyak ...
MELLYANA, Omega
core