Results 81 to 90 of about 370,495 (313)

Glycoxidized LDL increases lectin-like oxidized low density lipoprotein receptor-1 in diabetes mellitus

, 2009
Aims: LDL is subjected to glycoxidation in diabetes mellitus. We have evaluated the effect of glycoxidized LDL on lectin-like oxidized low density lipoprotein receptor-1 (LOX-1) expression in endothelial cells in vitro, as well as the relationship ...
Wong, Y, Bucala, R, Leng, L, Tan, KCB, Shiu, SWM   +4 more
core   +1 more source

A Microgel Platform Enables Site‐Specific Intestinal Delivery of Lactoferrin, Improving its Bioavailability for Targeted Alleviating Liver Injury and Colitis

Advanced Science, EarlyView.
This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan, Yixuan Li, Shanan Chen, Pengcheng Du, Kaiwen Wu, Hui Zhang, Kasper Hettinga, Lina Zhang, Gergely Toldi, Fazheng Ren, Yuan Li   +10 more
wiley   +1 more source

Isolation and in-vitro oxidation of human low density lipoproteins

International Journal of Medicine and Health Development, 1998
The role of low density lipoproteins (LDL) in the pathogensis of atherosclerosis has been gaining increasing importance. It is well accepted that LDL in their modified (i.e.
J C Igweh, N Leitinger, Rodregues Magarida, H Sinzinger   +3 more
doaj  

Honey improves lipid profile of diet-induced hypercholesterolemic rats

Universa Medicina, 2016
Background Coronary heart disease (CHD) is a major cause of morbidity and mortality throughout the world, including Indonesia. One of the risk factors for CHD is hypercholesterolemia.
Titis Nurmasitoh, Miranti Dewi Pramaningtyas   +1 more
doaj   +1 more source

LDL Receptors in Keratinocytes

Journal of Investigative Dermatology, 1992
The presence of sufficient amounts of cholesterol in the epidermis is necessary for proper functioning of plasma membranes in the viable epidermal cell layers and also for the barrier quality of lipid intercellular bilayers of the stratum corneum. Cholesterol can be generated by local epidermal synthesis, or imported from the circulation as low-density
Ponec, Maria, te Pas, Marinus F.W, Havekes, Louis, Boonstra, Johannes, Mommaas, A Mieke, Vermeer, Bert Jan   +5 more
openaire   +2 more sources

Effects of miR-27a/b on secretion of proinflammatory cytokines in ox-LDL- treated THP-1 macrophages.

, 2016
Effects of miR-27a/b on secretion of proinflammatory cytokines in ox-LDL- treated THP-1 macrophages.
Feng Yao (44334), Duo Gong (799287), Ping-Ping He (463143), Dan Liu (108669), Xi-Long Zheng (2342863), Min Zhang (111999), Chao-Ke Tang (463148), Gang Lan (799286), Yun-Cheng Lv (463141), Hai-Peng Cheng (799288), Yu-Lin Tan (799285), Wei-Dong Yin (665406), Liang Li (46069), Zhen-Wang Zhao (2816827), Xin-Ping Ouyang (463142), Wei Xie (16543)   +15 more
core   +1 more source

Targeting ANGPTL3 and IL‐33/ST2 Ameliorates Diabetic Kidney Disease by Reducing Lipotoxicity, Alleviating Inflammation and Inhibiting Fibrosis

Advanced Science, EarlyView.
Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li, Zhonglian Cao, Rongrui Zhou, Xu Cheng, Xiaozhi Hu, Shuwen Xu, Zihan Dou, Ling Du, Dianwen Ju   +8 more
wiley   +1 more source

Beneficial influence of low-density lipoprotein cholesterol on the endothelium in relation to endothelial repair

Environmental Health and Preventive Medicine
Background: Low-density lipoprotein cholesterol (LDLc) is regarded as a risk factor for endothelial dysfunction. However, LDLc stimulates the proliferation of hematopoietic stem cells (CD34-positive cells), which contribute to endothelial repair ...
Yuji Shimizu, Shin-Ya Kawashiri, Hirotomo Yamanashi, Seiko Nakamichi, Naomi Hayashida, Yasuhiro Nagata, Takahiro Maeda   +6 more
doaj   +1 more source

Efek minyak ikan toman (Channa micropeltes) terhadap kadar profil lipid mencit jantan (Mus musculus) model dislipidemia

Majalah Kedokteran Andalas, 2019
Tujuan: Untuk mengetahui efek minyak ikan toman (Channa micropeltes) terhadap profil lipid pada mencit jantan (Mus musculus). Metode: Penelitian ini adalah eksperimental laboratorium menggunakan rancangan randomized pre- dan post-test dengan menggunakan ...
Sadakata Sinulingga, Aprilia Putri, Intan Rahma Dewi, Melina Indah Sari, Mutiara Budi Azhar, Tri Suciati, Mariana Mariana, Subandrate Subandrate   +7 more
doaj   +1 more source

Effect of irisin on Bax, Bcl-2, and caspase-3 protein levels in ox-LDL-induced HUVECs.

, 2016
HUVECs were incubated with irisin and ox-LDL for 24 h. (A) The expression levels of caspase-3, Bax, and Bcl-2 were analyzed by western blot. GAPDH was used as a loading control. (B) Densitometric analysis of the related bands was performed. The data were
Zheng Zhou (152309), Shiwu Li (460656), Lijun Yang (356935), Xingli Wang (1466815), Haibo Song (648222), Yuan Zhang (41832), Lei Shao (227754), Qian Mu (779498), Qi Wu (263110), Fang Wang (105926), Dongqi Tang (136130), Fei Wu (117860), Miao Jiang (442328), Mingxiang Zhang (126631), Wen Zhang (7555), Liang Li (46069), Yuzhu Zhang (648223)   +16 more
core   +1 more source