Results 71 to 80 of about 370,495 (313)

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

Advanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang, Xiangyao Wang, Yaxin Wu, Liping Liu, Gaoshaer Nuerlan, Ahsawle Ozathaley, Xiaorui Zhang, Jinping Wang, Bowen Yang, Jing Mao, Yan Liu, Shiqiang Gong   +11 more
wiley   +1 more source

Synergistic effects of serum albumin and HDL cholesterol concentrations on serum oxidized LDL cholesterol concentration in obese individuals with normal glycoregulation and patients with type 2 diabetes mellitus [PDF]

Vojnosanitetski Pregled
Background/Aim. Serum albumin and high-density lipoprotein (HDL) cholesterol molecules have multiple physiological functions, including an antioxidant role in neutralizing the harmful effects of oxidized low-density lipoprotein (oxLDL).
Pejin Radoslav, Milankov Andrijana, Ičin Tijana, Bajkin Ivana, Niković Jelena, Jovanović Aleksandar, Tanackov Ilija   +6 more
doaj   +1 more source

The effects of miR-497 suppression on the proliferation and apoptosis of ox-LDL-induced HUVECs.

, 2016
(A) Cell cycle changes detected by a flow cytometer. The cells were stained with PI prior to detection. Suppression of miR-497 could partially increase the percentage of S-phase cells that were reduced by the addition of ox-LDL.
Shenming Wang (181422), Ridong Wu (418007), Mian Wang (153332), Xiangdong Xu (81057), Chen Yao (137375), Shi Tang (495124)   +5 more
core   +1 more source

Intestinal Source Control of Lipid Metabolism by Enzyme‐Probiotic Encapsulated, Spatiotemporal Crosslinked, and Small Intestine‐Adhesive Hydrogel Microspheres

Advanced Science, EarlyView.
A thiol‐modified alginate hydrogel microsphere‐encapsulated enzyme‐probiotic biohybrid (AKK‐COD) system has been developed to address the spatiotemporal delivery and colonization challenges of small intestine‐targeted probiotic for lipid metabolism regulation. The system exerts sequential functions of intragastric protection, small intestinal adhesion,
Xiaolin Wu, Weiwen Liang, Siqi He, Guangyuan Chen, Hui Zhou, Xinglong Wang, Yifei Li, Dingcai Wu, Bingna Zheng, Ruoxu Dou, Rongkang Huang   +10 more
wiley   +1 more source

PSYNDEX Tests Review für LDL - Lernfortschrittsdiagnostik Lesen

, 2010
This is a PSYNDEX Tests Review of LDL - Lernfortschrittsdiagnostik Lesen. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Mayer, Anne-Kathrin
core   +1 more source

Stage‐Specific H3K14 and H3K23 Succinylation Orchestrates Insect Metamorphosis and Oogenesis

Advanced Science, EarlyView.
Stage‐specific succinylation of histone H3 at lysine 14 and 23 differentially controls insect metamorphosis and oogenesis through distinct GPCR‐PKC signaling cascades, revealing an evolutionarily conserved epigenetic mechanism that coordinates key life‐history traits.
Yu‐Pu Jing, Lunjie Li, Libin Yang, Lin‐Jie Zhang, Qiang Yan, Ci Zhang, Zanrong Wen, Guangze Yu, Qian Li, Shutang Zhou   +9 more
wiley   +1 more source

Supplemental Material - Silencing p62 reduces ox-LDL-induced M1 polarization and inflammation in macrophages by inhibiting mTOR/NF-κB signaling pathways

, 2022
Supplemental Material for Silencing p62 reduces ox-LDL-induced M1 polarization and inflammation in macrophages by inhibiting mTOR/NF-κB signaling pathways by Wei Yang, Guangming Su and Yanhong Liu in European Journal of ...
Yanhong Liu (124527), Guangming Su (13107161), Wei Yang (109917)   +2 more
core   +1 more source

Lactoferrin Deficiency During Lactation Causes Adult Obesity‐Related Metabolic Disease Through Persistent Adipose Dysfunction Driven by Impaired Adipocyte Development

Advanced Science, EarlyView.
Lactational lactoferrin deficiency exerts lasting effects on epididymal adipose tissue development from lactation into adulthood: it impairs adipocyte hyperplasia and induces pathological hypertrophy, resulting in lower body weight yet exacerbated metabolic dysfunction under a high‐fat diet in adulthood.
Qin An, Yunxia Zou, Wenli Wang, Zhimei Cheng, Zhuoxing Zhang, Ruwei Liu, Xiong Wang, Kunlun Huang, Fangrong Ding, Yunping Dai, Qingyong Meng, Yali Zhang   +11 more
wiley   +1 more source

Towards an Open Architecture for LDL

, 1989
We extend LDL to allow programs to call external procedures and vice versa. This extension allows the modularization of LDL, since external predicates are equivalent to external procedures written in LDL.
Ravi Krishnamurthy, An Ldl, Danette Chimenti, Ruben Gamboa   +3 more
core