Results 11 to 20 of about 750,498 (385)
Oman Medical Journal, 2022 Objectives: We sought to estimate the percentage achievements of non-high-density lipoprotein cholesterol (non-HDL-C) target in patients with very high atherosclerotic cardiovascular diseases (ASCVD) risk stratified by triglyceride (TG) levels despite ...
Hilal Al-Sabti +23 more
doaj +1 more source
Electronegative LDL: A Circulating Modified LDL with a Role in Inflammation [PDF]
Mediators of Inflammation, 2013 Electronegative low density lipoprotein (LDL(−)) is a minor modified fraction of LDL found in blood. It comprises a heterogeneous population of LDL particles modified by various mechanisms sharing as a common feature increased electronegativity. Modification by oxidation is one of these mechanisms. LDL(−) has inflammatory properties similar to those of
Jordi Ordóñez Llanos +4 more
openaire +6 more sources
Journal of Medical and Scientific Research, 2023 Background: Dyslipidemia is one of the most prevalent risk factors contributing to atherosclerotic cardiovascular disease. Clinical trials have demonstrated that treatment of dyslipidemia reduces cardiovascular events.
Amit A +4 more
doaj +1 more source
Folia Medica Indonesiana, 2023 Highlights: 1. Uncertainty regarding the association between hypertension and the levels of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) signifies the need for more research, particularly in the realm of sex-specific analysis.
Arin Nurtya +4 more
doaj +1 more source
Liver Transplantation to Provide Low-Density-Lipoprotein Receptors and Lower Plasma Cholesterol in a Child with Homozygous Familial Hypercholesterolemia [PDF]
, 1984 A six-year-old girl with severe hypercholesterolemia and atherosclerosis had two defective genes at the low-density-lipoprotein (LDL) receptor locus, as determined by biochemical studies of cultured fibroblasts.
Cummings +9 more
core +1 more source
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease.
New England Journal of Medicine, 2006 BACKGROUND A low plasma level of low-density lipoprotein (LDL) cholesterol is associated with reduced risk of coronary heart disease (CHD), but the effect of lifelong reductions in plasma LDL cholesterol is not known.
Jonathan C. Cohen +3 more
semanticscholar +1 more source
Metabolism of low-density lipoproteins by cultured hepatocytes from normal and homozygous familial hypercholesterolemic subjects [PDF]
, 1986 The profoundly elevated concentrations of low-density lipoproteins (LDL) present in homozygous familial hypercholesterolemia lead to symptomatic cardiovascular disease and death by early adulthood.
Brewer, HB +6 more
core +1 more source
Lipid levels are inversely associated with infectious and all-cause mortality: international MONDO study results. [PDF]
, 2018 Cardiovascular (CV) events are increased 36-fold in patients with end-stage renal disease. However, randomized controlled trials to lower LDL cholesterol (LDL-C) and serum total cholesterol (TC) have not shown significant mortality improvements.
Canaud, Bernard +11 more
core +7 more sources
Correlation of fasting lipid profile in non-diabetic CKD patients on conservative management
National Board of Examinations Journal of Medical Sciences, 2023 Background- Chronic kidney disease is emerging as a major chronic disease worldwide. There is surge in incidence of CKD in developing countries that is likely to pose a major problem in both health and economic sector.
Deepak Sha K +2 more
doaj +1 more source
LDL protein nitration: Implication for LDL protein unfolding [PDF]
Archives of Biochemistry and Biophysics, 2008 Oxidatively- or enzymatically-modified low-density lipoprotein (LDL) is intimately involved in the initiation and progression of atherosclerosis. The in vivo modified LDL is electro-negative (LDL(-)) and consists of peroxidized lipid and unfolded apoB-100 protein.
Liana Asatryan +6 more
openaire +3 more sources