Intracellular transports and atherogenesis
There is a great progress in understanding the cellular and molecular aspects of atherosclerosis, which is one of the leading causes of death. Yet, there are questions regarding the cellular and metabolic mechanisms that lead to atherogenesis.
Alexander A. Mirоnоv +4 more
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Non-high-density lipoprotein (non-HDL) cholesterol in adolescence as a predictor of atherosclerotic cardiovascular diseases in adulthood [PDF]
Defined as the total cholesterol minus high-density lipoprotein (HDL), non-HDL cholesterol has been increasingly acknowledged as a measure of risk estimation for developing atherosclerotic cardiovascular diseases (ASCVD).
Saeed Shoar +7 more
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LDL protein nitration: Implication for LDL protein unfolding [PDF]
Oxidatively- or enzymatically-modified low-density lipoprotein (LDL) is intimately involved in the initiation and progression of atherosclerosis. The in vivo modified LDL is electro-negative (LDL(-)) and consists of peroxidized lipid and unfolded apoB-100 protein.
Ryan T, Hamilton +6 more
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Zi Han Zhai,1,2 Jun Hao Ning,1,2 Linda Dong-Ling Wang1,3 1Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, 225001, People’s Republic of China; 2Jiangsu Key Laboratory of Experimental & Translational Non-Coding RNA ...
Zhai ZH, Ning JH, Wang LDL
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In this article, the history of the LDL receptor is recounted by its codiscoverers. Their early work on the LDL receptor explained a genetic cause of heart attacks and led to new ways of thinking about cholesterol metabolism. The LDL receptor discovery also introduced three general concepts to cell biology: receptor-mediated endocytosis, receptor ...
Joseph L, Goldstein, Michael S, Brown
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Association of CYP2D6*4 Polymorphism With Response to Atorvastatin in Patients With High Low-Density Lipoprotein Level in Northern Iran, Guilan Provice [PDF]
Background: People who take statins respond differently to them due to genetic differences. One of the most significant enzymes involved in drug metabolism is cytochrome P450 2D6 (CYP2D6) enzyme, coded by the CYP2D6 gene.
Raziyeh Asadollahpour +8 more
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A Meta-Analysis of eHealth Interventions on Ischaemic Heart Disease Health Outcomes
Background: Electronic Health (eHealth) interventions as a secondary prevention tool to empower patients’ health in decision-making and behaviour. Objective: With the growing body of evidence supporting the use of eHealth interventions, the intention is ...
Puteri Sofia Nadira Megat Kamaruddin +4 more
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The effect of 12 weeks of calistenic exercises in the workplace on body composition indices and some blood factors of middle-aged female employees [PDF]
1. Avancini A, Trestini I, Tregnago D, Wiskemann J, Lanza M, Milella M, Pilotto S. Physical activity for oncological patients in COVID-19 era: no time to relax. JNCI Cancer Spectrum. 2020;4(6):pkaa071. 2.
mehdi ghafari +3 more
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PCSK9 Inhibitor Therapy as an Alternative for Statin Intolerance
Scientific relevance. The main cause of cardiovascular pathologies is atherosclerosis, which is secondary to lipid metabolism disorders, in particular, the accumulation of low-density lipoprotein (LDL) cholesterol.
K. O. Shnaider +3 more
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Increased Serum Lipid Levels in Patients with Subjective Tinnitus [PDF]
Introduction: The aim was to investigate the link between tinnitus and serum levels of total cholesterol (TC), triglyceride (TRG), low-density (LDL) and high-density lipoprotein (HDL) in the central anatolian Turkish population.
Deniz Avcı
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