Results 21 to 30 of about 750,498 (385)

Safety and Efficacy of Bempedoic Acid to Reduce LDL Cholesterol

New England Journal of Medicine, 2019
Background Short‐term studies have shown that bempedoic acid, an inhibitor of ATP citrate lyase, reduces levels of low‐density lipoprotein (LDL) cholesterol.
K. Ray, H. Bays, A. Catapano, N. Lalwani, L. Bloedon, L. Sterling, P. Robinson, C. Ballantyne   +7 more
semanticscholar   +1 more source

Platelet interaction with bioactive lipids formed by mild oxidation of low-density lipoprotein [PDF]

, 2006
Oxidation of low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic mediators that play a crucial role in cardiovascular and inflammatory diseases.
Siess, Wolfgang
core   +1 more source

Association of Triglyceride-Lowering LPL Variants and LDL-C–Lowering LDLR Variants With Risk of Coronary Heart Disease

Journal of the American Medical Association (JAMA), 2019
Importance Triglycerides and cholesterol are both carried in plasma by apolipoprotein B (ApoB)–containing lipoprotein particles. It is unknown whether lowering plasma triglyceride levels reduces the risk of cardiovascular events to the same extent as ...
B. Ference, J. Kastelein, K. Ray, H. Ginsberg, M. Chapman, C. Packard, U. Laufs, C. Oliver‐Williams, A. Wood, A. Butterworth, E. di Angelantonio, J. Danesh, S. Nicholls, Deepak L. Bhatt, M. Sabatine, A. Catapano   +15 more
semanticscholar   +1 more source

Hong Kong Chinese parental attitudes towards vaccination and associated socio-demographic disparities [PDF]

, 2016
Background: Most previous studies on parental attitudes towards vaccination focused on a disease-specific vaccine. In this study we describe general attitudes towards vaccination in Chinese parents and associated socio-demographic disparities.
Fielding, R, Lam, WWT, Wang, LDL
core   +1 more source

Evaluation of Serum HDL and LDL levels in Type II Diabetes Mellitus

Journal of Lumbini Medical College, 2013
Introduction: Diabetes mellitus is a type of metabolic disorder characterized by hyperglycemia resulting from defect in insulin secretion, insulin action or both.
K R Joshi, K K Hiremath, S P Gupta
doaj   +1 more source

Possibilities of transition of the strategy from glucosecentricity to organoprotection when prescribing antidiabetic drugs in patients with type 2 diabetes mellitus in the perimenapause

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2023
Obesity, type 2 diabetes mellitus and cardiovascular diseases associated with these conditions remain one of the largest global health problems. According to statistics, at least 90 % of patients with type 2 diabetes mellitus are obese or at least ...
V. V. Smirnov, Yu. B. Semenova, A. B. Shapovalova, N. N. Matveeva, V. A. Zubarev   +4 more
doaj   +1 more source

Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis.

Journal of the American Medical Association (JAMA), 2016
IMPORTANCE The comparative clinical benefit of nonstatin therapies that reduce low-density lipoprotein cholesterol (LDL-C) remains uncertain. OBJECTIVE To evaluate the association between lowering LDL-C and relative cardiovascular risk reduction across
Michael G. Silverman, B. Ference, K. Im, S. Wiviott, R. Giugliano, S. Grundy, E. Braunwald, M. Sabatine   +7 more
semanticscholar   +1 more source

Cervical cancer prevention practices through screening and vaccination: A cross-sectional study among Hong Kong Chinese women [PDF]

, 2015
postprin
Fielding, R, Lam, WWT, Wang, LDL
core   +1 more source

Performance evaluation of green logistics: Paving the way towards circular economy

Cleaner Logistics and Supply Chain, 2022
The linear flow of production causes several problems, mainly concerning the environmental pillar of sustainability. In logistics, a more circular and green production system is linked to the implementation of Green Logistics (GL), which aims to reduce ...
E.D. de Souza, J.C. Kerber, M. Bouzon, C.M.T. Rodriguez   +3 more
doaj  

Mechanisms of dysregulation of low-density lipoprotein receptor expression in vascular smooth muscle cells by inflammatory cytokines [PDF]

, 2006
Objective - Although inflammation is a recognized feature of atherosclerosis, the impact of inflammation on cellular cholesterol homeostasis is unclear.
Ma, KL, Moorhead, JF, Powis, SH, Ruan, XZ, Tao, JL, Varghese, Z, Wheeler, DC   +6 more
core   +1 more source