Results 41 to 50 of about 965,123 (374)

Remnant cholesterol predicts cardiovascular disease beyond LDL and ApoB: a primary prevention study.

European Heart Journal, 2021
AIMS Emerging evidence suggests that remnant cholesterol (RC) promotes atherosclerotic cardiovascular disease (ASCVD). We aimed to estimate RC-related risk beyond low-density lipoprotein cholesterol (LDL-C) and apolipoprotein B (apoB) in patients without
Renato Quispe, S. Martin, E. Michos, Isha Lamba, R. Blumenthal, Anum Saeed, J. Lima, R. Puri, Sarah O. Nomura, M. Tsai, J. Wilkins, C. Ballantyne, S. Nicholls, S. Jones, M. Elshazly   +14 more
semanticscholar   +1 more source

Cholesterol deposition in macrophages: foam cell formation mediated by cholesterol-enriched oxidized low density lipoprotein.

Journal of Lipid Research, 1997
Oxidized low density lipoprotein (LDL) is thought to mediate the transformation of macrophages to cholesterol-rich foam cells. Yet convincing evidence for this process is lacking in vitro.
P Greenspan, H Yu, F Mao, R L Gutman
doaj   +1 more source

Which lipid measurement should we monitor? An analysis of the LIPID study [PDF]

, 2014
OBJECTIVES: To evaluate the optimal lipid to measure in monitoring patients, we assessed three factors that influence the choice of monitoring tests: (1) clinical validity; (2) responsiveness to therapy changes and (3) the size of the long-term ‘signal ...
Glasziou, Paul P., Irwig, Les, Kirby, Adrienne C., Simes, R. John, Tonkin, Andrew M.   +4 more
core   +1 more source

Influence of an atherogenic diet on the structure of swine low density lipoproteins

Journal of Lipid Research, 1980
Five groups of three swine each were fed a basal diet supplemented with 15% tallow and either 0.0, 1.0, 1.5, 2.0%, or 2.5% cholesterol. The animals were studied over a period of 9 weeks to observe changes in plasma lipids and low density lipoproteins ...
H J Pownall, R L Jackson, R I Roth, A M Gotto, J R Patsch, F A Kummerow   +5 more
doaj   +1 more source

Quantifying Atherogenic Lipoproteins: Current and Future Challenges in the Era of Personalized Medicine and Very Low Concentrations of LDL Cholesterol. A Consensus Statement from EAS and EFLM.

Clinical Chemistry, 2018
BACKGROUND The European Atherosclerosis Society-European Federation of Clinical Chemistry and Laboratory Medicine Consensus Panel aims to provide recommendations to optimize atherogenic lipoprotein quantification for cardiovascular risk management ...
M. Langlois, M. Chapman, C. Cobbaert, S. Mora, A. Remaley, E. Ros, G. Watts, J. Borén, H. Baum, E. Bruckert, A. Catapano, O. Descamps, A. von Eckardstein, P. Kamstrup, G. Kolovou, F. Kronenberg, A. Langsted, K. Pulkki, N. Rifai, G. Sypniewska, O. Wiklund, B. Nordestgaard   +21 more
semanticscholar   +1 more source

Lipoprotein metabolism in familial hypercholesterolemia: Serial assessment using a one-step ultracentrifugation method

Practical Laboratory Medicine, 2015
Objectives: It is well known that familial hypercholesterolemia (FH) is a common inherited disorder that can markedly elevate the level of plasma LDL cholesterol.
Hayato Tada, Masa-aki Kawashiri, Atsushi Nohara, Akihiro Inazu, Hiroshi Mabuchi, Masakazu Yamagishi, Kenshi Hayashi   +6 more
doaj   +1 more source

An integrated mathematical model of cellular cholesterol biosynthesis and lipoprotein metabolism [PDF]

, 2018
Cholesterol regulation is an important aspect of human health. In this work we bring together and extend two recent mathematical models describing cholesterol biosynthesis and lipoprotein endocytosis to create an integrated model of lipoprotein ...
Pool, Frances, Sweby, Peter K., Tindall, Marcus J.   +2 more
core   +2 more sources

Carbohydrate Restriction-Induced Elevations in LDL-Cholesterol and Atherosclerosis: The KETO Trial. [PDF]

JACC Adv
Budoff M, Manubolu VS, Kinninger A, Norwitz NG, Feldman D, Wood TR, Fialkow J, Cury R, Feldman T, Nasir K.   +9 more
europepmc   +3 more sources

Addressing dyslipidemic risk beyond LDL-cholesterol [PDF]

Journal of Clinical Investigation, 2022
Despite the success of LDL-lowering drugs in reducing cardiovascular disease (CVD), there remains a large burden of residual disease due in part to persistent dyslipidemia characterized by elevated levels of triglyceride-rich lipoproteins (TRLs) and reduced levels of HDL.
Alan R. Tall, David G. Thomas, Ainara G. Gonzalez-Cabodevilla, Ira J. Goldberg   +3 more
openaire   +3 more sources

Interaction of aging and dietary fat in the regulation of low density lipoprotein transport in the hamster.

Journal of Lipid Research, 1989
These studies were undertaken to examine the effect of aging on low density lipoprotein (LDL) metabolism in the male hamster. When the hamsters were maintained on a low-cholesterol, low-triglyceride diet, rates of LDL transport in the various tissues of ...
D K Spady, J M Dietschy
doaj   +1 more source