Results 181 to 190 of about 2,612,734 (405)

Exploring heart failure prevalence and dimensions: A comprehensive NT‐proBNP study in high‐risk primary care patients

ESC Heart Failure, EarlyView.
The diagnostic pathway of high‐risk primary care patients through NT‐proBNP. Abstract Introduction Early detection of heart failure (HF), particularly in asymptomatic individuals, is essential for timely intervention. This study aimed to determine the prevalence of HF among high‐risk individuals in primary care using N‐terminal probrain natriuretic ...
Ahmet Celik, Emrah Yesil, Unal Kılıç, Gizem Akcay Ozyurt, Selman Aytimur, Mustafa Demir, Huseyin Naci Eker, Ayse Siddika Col, Cemil Ilker Altiparmak, Mustafa Ergen, Selen Bozkaya, Ismail Sefa Okyay, Ibrahim Ethem Kerem, Kiristin Marina Arap, Melike Yirtar, Deniz Korkmaz, Ali Kırdağ, Ismail Turkay Ozcan   +17 more
wiley   +1 more source

Identification of a novel Arg→Cys mutation in the LDL receptor that contributes to spontaneous hypercholesterolemia in pigs

Journal of Lipid Research, 1999
We previously carried out genetic and metabolic studies in a partially inbred herd of pigs carrying cholesterol-elevating mutations. Quantitative pedigree analysis indicated that apolipoprotein (apo)B and a second major gene were responsible for the ...
Kurt A.A. Grunwald, Kathryn Schueler, Patricia J. Uelmen, Beth A. Lipton, Mary Kaiser, Kimberly Buhman, Alan D. Attie   +6 more
doaj  

ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells. [PDF]

Nat Commun, 2023
Lee J, Lee H, Lee H, Shin M, Shin MG, Seo J, Lee EJ, Park SA, Park S.   +8 more
europepmc   +1 more source

Stoichiometric Binding of Low Density Lipoprotein (LDL) and Monoclonal Antibodies to Ldl Receptors in a Solid Phase Assay

, 1989
Ian R. van Driel, Mark S. Brown, J L Goldstein   +2 more
openalex   +1 more source

Dapagliflozin effect on functional mitral regurgitation and myocardial remodelling: The DEFORM trial

ESC Heart Failure, EarlyView.
Abstract Aims Functional mitral regurgitation (FMR) is associated with adverse outcomes in patients with heart failure, and current guideline‐directed medical therapy (GDMT) offers limited efficacy in managing FMR. This study aims to evaluate the therapeutic impact of the sodium‐glucose cotransporter 2 inhibitor (SGLT2i) dapagliflozin in patients with ...
Zhuoshan Huang, Rui Fan, Shaozhao Zhang, Junlin Zhong, Yiquan Huang, Peihan Xie, Shanshan Yin, Xiaomin Ye, Xinghao Xu, Rihua Huang, Zhenyu Xiong, Yue Guo, Menghui Liu, Yifen Lin, Suhua Li, Xiaoxian Qian, Jinlai Liu, Xiaodong Zhuang, Xinxue Liao   +18 more
wiley   +1 more source

Low density lipoprotein metabolism in the normal to moderately elevated range of plasma cholesterol: comparisons with familial hypercholesterolemia

Journal of Lipid Research, 1983
Low density lipoprotein (LDL) metabolism was investigated using a pulse injection of 125I-labeled LDL in 20 subjects who did not have familial hypercholesterolemia (FH) (plasma cholesterol 160-297 mg/dl) and in 9 subjects who did have heterozygous FH ...
L A Simons, S Balasubramaniam, J Holland
doaj  

Natto consumption suppresses atherosclerotic plaque progression in LDL receptor-deficient mice transplanted with iRFP-expressing hematopoietic cells. [PDF]

Sci Rep, 2023
Kawamata T, Wakimoto A, Nishikawa T, Ikezawa M, Hamada M, Inoue Y, Kulathunga K, Salim FN, Kanai M, Nishino T, Gentleman K, Liu C, Mathis BJ, Obana N, Fukuda S, Takahashi S, Taya Y, Sakai S, Hiramatsu Y.   +18 more
europepmc   +1 more source

Simultaneous visualization of LDL receptor distribution and clathrin lattices on membranes torn from the upper surface of cultured cells. [PDF]

, 1991
David A. Sanan, R G Anderson
openalex   +1 more source

The discovery of PCSK9 inhibitors: A tale of creativity and multifaceted translational research. [PDF]

, 2013
Elguindy, A, Yacoub, MH
core   +1 more source

Prognostic value of lipid parameters among patients with heart failure: A systematic review and meta‐analysis

ESC Heart Failure, EarlyView.
Abstract Aims We sought to evaluate the prognostic value of different lipid parameters in patients with heart failure (HF). Methods and Results Electronic databases including MEDLINE, Embase, CENTRAL, and Web of Science were searched to identify studies that reported the association of any of the four lipid parameters [total cholesterol (TC), high ...
Ahmed Sayed, Hesham Afify, Malak Munir, Ibrahim ElGarhy, Omar Shazly, Mohamed ElRefaei, Saeed Ahmed, Ahmed Mazen Amin, Omar Chikh Amine, Islam Y. Elgendy   +9 more
wiley   +1 more source