Results 161 to 170 of about 1,464,846 (295)

Effect of type 2 diabetes on the inducible degrader of LDL receptor. [PDF]

J Lipid Res, 2023
Lam S, Lui DTW, Shiu SWM, Wong Y, Tan KCB.   +4 more
europepmc   +1 more source

Left ventricular diastolic dysfunction worsens prognosis in patients with heart failure due to dilated cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1183-1193, April 2025.
Abstract Aims The prognostic significance of left ventricular (LV) diastolic dysfunction (LVDD) severity in patients with dilated cardiomyopathy (DCM) remains uncertain. This study aimed to evaluate the association of LVDD severity and elevated left atrial pressure (eLAP) with patient outcomes in stable, non‐acutely decompensated patients with DCM ...
Mateusz Winiarczyk, Ewa Dziewięcka, Sylwia Wiśniowska‐Śmiałek, Agnieszka Stępień, Katarzyna Graczyk, Agata Leśniak‐Sobelga, Marta Hlawaty, Jakub Woźniak, Maryia Savitskaya, Katarzyna Holcman, Magdalena Kostkiewicz, Piotr Podolec, Paweł Rubiś   +12 more
wiley   +1 more source

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

Autophagy regulates MK-2206-induced LDL receptor expression and cholesterol efflux pathways. [PDF]

PLoS One
Sundvold H, Strøm TB.
europepmc   +1 more source

The effect of anti‐seizure medications on exposure to statins: A systematic review and meta‐analysis

Epileptic Disorders, EarlyView.
Abstract Objectives Antiseizure medications (ASMs) can reduce the efficacy of statin treatment, partly due to reduction in statin concentrations. In this systematic review and network meta‐analysis (NMA), we compared the effects of ASMs and the prototypical enzyme inducer rifampin on statin exposure.
Sharon Valiyev Huino, Hagar Cohen, Bruria Hirsh Raccah, Tomer Ben‐Shushan, Ilan Matok, Sara Eyal   +5 more
wiley   +1 more source

Functional characterization of 16 variants found in the LDL receptor gene. [PDF]

J Lipid Res
Konečná K, Přerovská T, Loja T, Fajkusová L, Koutná J, Kramárek M, Alves AC, Bourbon M, Freiberger T, Tichý L.   +9 more
europepmc   +1 more source

A randomized controlled trial of a multimodality digital health intervention to aid the delivery of the modified ketogenic diet therapy for epilepsy: The Keto eCoach trial protocol

Epilepsia Open, EarlyView.
Abstract Objective Dietary therapy is an effective treatment for drug‐resistant epilepsy; however, low adherence presents a significant barrier to use in the clinical setting. This study aims to evaluate a multimodality digital health intervention to overcome this barrier and improve outcomes in adults undertaking the modified ketogenic diet for ...
Neha Kaul, Lucy Vivash, Susanna Chen, Lillian King, Hannah Johns, Leonid Churilov, Zhibin Chen, John‐Paul Nicolo, Danielle Heaven, Ella Meredith, Ryan Ervine, Lisa Todd, Bernadette Zappa, Zanfina Ademi, Gopisankar Mohanannair Geethadevi, Michael Erlichster, Efstratios Skafidas, Terence J. O'Brien, Patrick Kwan   +18 more
wiley   +1 more source

Pathways and Molecular Mechanisms Governing LDL Receptor Regulation. [PDF]

Circ Res
Schmidt HM, Jarrett KE, de Aguiar Vallim TQ, Tarling EJ.   +3 more
europepmc   +1 more source

Higher Craving and Pleasure in Response to Exercise‐Related Cues in Patients With Anorexia Nervosa and Exercise Dependence

European Eating Disorders Review, EarlyView.
ABSTRACT Background Physical activity is common in patients with anorexia nervosa (AN), who often reported symptoms consistent with exercise dependence. Craving, the subjective urge to engage in a specific behaviour, is an important mechanism in the development of addiction and could be triggered by cues from the environment.
Giammarco Cascino, Laura Di Lodovico, Rossella Ceres, Rosa Cerra, Stefania Landi, Antonella Boccia, Alessio Maria Monteleone, Philip Gorwood, Palmiero Monteleone   +8 more
wiley   +1 more source

Vascular Contractile and Structural Properties in Diet-Induced Atherosclerosis-Prone CB₁-LDL Receptor Double Knockout Animal Model. [PDF]

Biomedicines
Shenker-Horváth K, Vass Z, Bányai B, Kiss S, Kovács KB, Kiss J, Trenka AP, Gém JB, Szénási A, Horváth EM, Jakus Z, Nádasy GL, Dörnyei G, Szekeres M.   +13 more
europepmc   +1 more source