Microbiota‐targeted therapeutic strategies in hematological disorders. aHSCT: Transplanted immune cells from the donor may attack the recipient's tissues, especially when damage to the intestinal epithelium disrupts the gut microbiota, contributing to GVHD. Maintaining a balanced gut microbiota that supports immune regulation helps reduce GVHD risk and
Alireza Molajafari +3 more
wiley +1 more source
Oxidation of low-density lipoprotein by hemoglobin causes pulmonary microvascular endothelial barrier dysfunction through lectin-like oxidized LDL receptor 1. [PDF]
Meegan JE +6 more
europepmc +1 more source
ABSTRACT Background Antiretroviral therapy has transformed HIV into a chronic condition, yet cardiac injury remains a major issue. Purpose To assess the ability of cardiac MR imaging markers to predict cardiac injury and disease progression in HIV‐infected individuals. Study Type Prospective.
Chunyan Deng +5 more
wiley +1 more source
LDL receptor in alphavirus entry: structural analysis and implications for antiviral therapy. [PDF]
Wang N +10 more
europepmc +1 more source
ABSTRACT Background Long‐term blood pressure variability (BPV) is associated with cognitive decline, yet the underlying mechanisms have not been fully elucidated. Purpose To investigate the associations between long‐term BPV and hippocampal subfield volume and cognitive function and to assess the mediation effect of hippocampal subfield volume.
Fei Li +17 more
wiley +1 more source
Non‐linear association between tooth loss and cardiovascular diseases among middle‐aged adults
Abstract Background Although positive associations between fewer remaining teeth and an increased risk of various systemic diseases have been reported, the precise dose‐response relationship has not been fully clarified. This study aimed to evaluate the non‐linearity of the dose‐response association between the number of lost teeth and the risk of ...
Taro Kusama +7 more
wiley +1 more source
Gene expression patterns of the LDL receptor and its inhibitor Pcsk9 in the adult zebrafish brain suggest a possible role in neurogenesis. [PDF]
Gence L +6 more
europepmc +1 more source
The effects of royal jelly on human health: A narrative review of clinical studies
Abstract Royal jelly (RJ) is a natural bioactive substance with documented effects on human health. This narrative review synthesizes evidence from clinical and clinically relevant experimental studies evaluating the therapeutic potential of RJ.
Georgios Goras +2 more
wiley +1 more source
Apolipoprotein O modulates cholesterol metabolism via NRF2/CYB5R3 independent of LDL receptor. [PDF]
Chen J +10 more
europepmc +1 more source
Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz +10 more
wiley +1 more source

