Results 181 to 190 of about 1,464,846 (295)

Cold shock domain-containing protein E1 is a posttranscriptional regulator of the LDL receptor. [PDF]

Sci Transl Med, 2022
Smith GA, Padmanabhan A, Lau BH, Pampana A, Li L, Lee CY, Pelonero A, Nishino T, Sadagopan N, Xia VQ, Jain R, Natarajan P, Wu RS, Black BL, Srivastava D, Shokat KM, Chorba JS.   +16 more
europepmc   +1 more source

Safety and Metabolic Effects of Withania somnifera Seed Extract and Powder in Rats: Insights From DPP‐4 Molecular Docking

Food Safety and Health, EarlyView.
Withania somnifera seed extract and powder improved metabolic parameters in rats, particularly at higher extract doses, without evident hepatic, renal, hematological, or histopathological toxicity. Molecular docking further predicted strong DPP‐4 inhibitory potential of withanone, supporting the antidiabetic potential of W. somnifera seeds.
Muhammad Usman Khalid, Muhammad Waqar, Muhammad Tauseef Sultan, Muhammad Maaz, Ahmad Mujtaba Noman, Hassan Raza, Muhammad Israr, Djilali Benabdelmoumene, Abdifetah Ibrahim Omar   +8 more
wiley   +1 more source

Multimodal Therapy Achieves Secondary Prevention LDL-C Targets in LDL-Receptor Null Homozygous Familial Hypercholesterolemia. [PDF]

JACC Case Rep
Alkhairy A, Xiang P, Khoo JK, Taylor CM, Francis GA.   +4 more
europepmc   +1 more source

PANDORA-Seq unveils the hidden small noncoding RNA landscape in atherosclerosis of LDL receptor-deficient mice. [PDF]

J Lipid Res, 2023
Hernandez R, Shi J, Liu J, Li X, Wu J, Zhao L, Zhou T, Chen Q, Zhou C.   +8 more
europepmc   +1 more source

Effectiveness of a Primary‐Care‐Centered Integrated Care Intervention for Stratified Cardiovascular Risk Control in China: Study Protocol for a Pragmatic Cluster Randomized Controlled Trial

Health Care Science, EarlyView.
This study developed a multifaceted intervention to strengthen primary care for cardiovascular risk management by leveraging both primary care and county hospitals in rural China. The purpose of this multicentre, cluster‐randomized controlled trial is to evaluate the effectiveness of intervention on the prevention of cardiovascular risks among patients
Weijia Lu, Xinxin Xia, Ziming Wang, Yaoyun Zhang, Yiting Lin, Wuxiang Xie, Jin Xu   +6 more
wiley   +1 more source

AFM reveals differential effects of acidification on LDL- and oxidized LDL-receptor interactions: biomechanical implications in atherogenesis. [PDF]

Cell Mol Biol Lett
Wang K, Sun C, Zhuang H, Jiang XC, Chen Y.   +4 more
europepmc   +1 more source

LDL receptor-mediated endocytosis of <i>Escherichia coli</i> α-hemolysin mediates renal epithelial toxicity. [PDF]

Proc Natl Acad Sci U S A
Kuhn HW, Smither MR, Jin RJ, Collins CA, Ma H, Sina J, Gaut JP, Diamond MS, Hunstad DA.   +8 more
europepmc   +1 more source

Resveratrol Mediates Anti-Atherogenic Actions In Vitro and in LDL Receptor-Deficient Mice Fed a High-Fat Diet via Antioxidant, Anti-Inflammatory and Plaque-Stabilising Activities. [PDF]

Antioxidants (Basel)
Alahmadi A, Alotibi R, Chan YH, Taha S, Rifqi D, Alshehri N, Alalawi S, Alradi F, Gibbs A, Hughes TR, Ramji DP.   +10 more
europepmc   +1 more source

LDL receptor promotes urinary tract infection by α-hemolysin-producing <i>Escherichia coli</i> and long-term histopathologic sequelae in the kidney. [PDF]

Proc Natl Acad Sci U S A
Possenriede L, Sendtner GW, Falahat P, Miranda J, Schmidt A, Ludwig KU, von Vietinghoff S.   +6 more
europepmc   +1 more source

Epigenetic Predictors of Smoking: External Validation and Association With Smoking‐Related Cancer Risk

International Journal of Cancer, EarlyView.
ABSTRACT Tobacco smoking has a strong influence on DNA methylation (DNAm), enabling the development of DNAm‐based smoking predictors, yet external evaluations of these have remained limited. We aimed to assess six DNAm‐based smoking predictors in a large sample of middle‐aged and older Australians for (i) their accuracy and reliability, and (ii) their ...
Xiaoyu Fan, Danmeng Lily Li, Allison M. Hodge, Julie K. Bassett, Nina Afshar, Melissa C. Southey, Graham G. Giles, Roger L. Milne, Pierre‐Antoine Dugué   +8 more
wiley   +1 more source