Results 191 to 200 of about 140,038 (304)

PANDORA-Seq unveils the hidden small noncoding RNA landscape in atherosclerosis of LDL receptor-deficient mice. [PDF]

J Lipid Res, 2023
Hernandez R, Shi J, Liu J, Li X, Wu J, Zhao L, Zhou T, Chen Q, Zhou C.   +8 more
europepmc   +1 more source

Associations of C‐Reactive Protein–Triglyceride–Glucose Index With the Incidence and Progression of Cardiometabolic Multimorbidity in Middle‐Aged and Older Chinese Individuals: A Prospective Cohort Study From CHARLS

iLABMED, EarlyView.
This study investigated the association between C‐reactive protein‐triglyceride‐glucose index (CTI) and cardiometabolic multimorbidity (CMM) over a 9‐year follow‐up in a Chinese middle‐aged and older population. Higher CTI levels were significantly associated with an increased risk of CMM.
Zhengfeng Wu, Honghong Zhang, Yajun Zheng, Haijing Zhao, Jie Liu, Yuhan Ma, Yuqi Liu   +6 more
wiley   +1 more source

Resveratrol Mediates Anti-Atherogenic Actions In Vitro and in LDL Receptor-Deficient Mice Fed a High-Fat Diet via Antioxidant, Anti-Inflammatory and Plaque-Stabilising Activities. [PDF]

Antioxidants (Basel)
Alahmadi A, Alotibi R, Chan YH, Taha S, Rifqi D, Alshehri N, Alalawi S, Alradi F, Gibbs A, Hughes TR, Ramji DP.   +10 more
europepmc   +1 more source

A Review of Progress on Targeting LDL Receptor-Dependent and -Independent Pathways for the Treatment of Hypercholesterolemia, a Major Risk Factor of ASCVD. [PDF]

Cells, 2023
Srivastava RAK.
europepmc   +1 more source

Bifidobacterium animalis BGI‐L99 Ameliorates Polycystic Ovary Syndrome by Modulating the Gut Microbiota‐Bile Acid‐IL‐22 Axis

iMetaMed, EarlyView.
Polycystic ovary syndrome (PCOS) is described as a complex endocrine‐metabolic disorder frequently accompanied by reproductive dysfunction and depression‐like behaviors. During PCOS progression, gut microbiota dysbiosis and systemic bile acid disturbances co‐occur, severely disrupting host immune and metabolic homeostasis. B.
Haoyu Wang, Weixuan Chen, Xiaofang Li, Xiaohong Lu, Tianli Liu, Jiarui Liang, Yajie Wang, Mengzhen Jia, Ruiyu Zhang, Yuzheng Gu, Jielei Zhu, Jiayi Ma, Zhinan Wu, Yiyi Zhong, Haifeng Zhang, Tao Yang, Liang Xiao, Zhigang Liu, Yuanqiang Zou   +18 more
wiley   +1 more source

AFM reveals differential effects of acidification on LDL- and oxidized LDL-receptor interactions: biomechanical implications in atherogenesis. [PDF]

Cell Mol Biol Lett
Wang K, Sun C, Zhuang H, Jiang XC, Chen Y.   +4 more
europepmc   +1 more source

Probiotics‐derived postbiotics improve host metabolic syndrome by activating the adipocyte thermogenic signaling pathway in high‐fat diet‐fed mice

iMetaOmics, EarlyView.
This schematic illustrates how probiotics‐derived postbiotics (PLBK®1–5) combat high‐fat diet‐induced obesity. Postbiotics remodel gut microbiota, boosting beneficial metabolites. These metabolites activate adipocyte thermogenesis (Ucp1/AMPK pathway), resulting in reduced body weight, improved insulin sensitivity, and alleviated hepatic steatosis in ...
Ye Tian, Liujing Huang, Yifan Liu, Xudong Mai, Yanbo Cheng, Bingdong Liu, Yixin Chen, Liwei Xie   +7 more
wiley   +1 more source

LDL receptor promotes urinary tract infection by α-hemolysin-producing <i>Escherichia coli</i> and long-term histopathologic sequelae in the kidney. [PDF]

Proc Natl Acad Sci U S A
Possenriede L, Sendtner GW, Falahat P, Miranda J, Schmidt A, Ludwig KU, von Vietinghoff S.   +6 more
europepmc   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

LDL receptor-mediated endocytosis of <i>Escherichia coli</i> α-hemolysin mediates renal epithelial toxicity. [PDF]

Proc Natl Acad Sci U S A
Kuhn HW, Smither MR, Jin RJ, Collins CA, Ma H, Sina J, Gaut JP, Diamond MS, Hunstad DA.   +8 more
europepmc   +1 more source