Results 31 to 40 of about 226,507 (202)
MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases. [PDF]
, 2014 Low-grade systemic inflammation is often associated with metabolic syndrome, which plays a critical role in the development of the obesity-associated inflammatory diseases, including insulin resistance and atherosclerosis.
DeFranco, Anthony L +19 more
core +2 more sources
Adropin: An endocrine link between the biological clock and cholesterol homeostasis [PDF]
, 2018 This article explores two translation models circling around the key issue “equivalence” in translation studies. They are the Jerome Model and the Horace Model. They differentiate from each other in the aspects of the translating priorities and purposes,
et al,, Rao, D. C
core +4 more sources
Measurement of total hepatic low density lipoprotein receptor levels in the hamster.
Journal of Lipid Research, 1993 The ability to measure the total concentration of low density lipoprotein (LDL) receptors in hepatic tissues is of crucial importance to understanding changes in hepatic cholesterol metabolism.
PG Cosgrove, BJ Gaynor, HJ Harwood, Jr
doaj +1 more source
Rapid fluorometric assay of LDL receptor activity by DiI-labeled LDL.
Journal of Lipid Research, 1993 DiI-LDL (3,3'-dioctadecylindocarbocyanine-low density lipoprotein) has been extensively used in morphological and microscopic studies of receptor-mediated metabolism of LDL in many cell lines.
ZF Stephan, EC Yurachek
doaj +1 more source
Human Coronary Smooth Muscle Cells Internalize Versican-Modified LDL Through LDL Receptor–Related Protein and LDL Receptors [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2002 Versican-like proteoglycans are the main component of the intimal extracellular matrix interacting with low density lipoprotein (LDL). The aim of this study has been to investigate the receptors involved in versican-modified LDL uptake by human vascular smooth muscle cells (VSMCs). We have found that versican-LDL interaction leads to the following: (1)
Llorente-Cortés, Vicenta +4 more
openaire +3 more sources
Ezetimibe therapy: mechanism of action and clinical update. [PDF]
, 2012 The lowering of low-density lipoprotein cholesterol (LDL-C) is the primary target of therapy in the primary and secondary prevention of cardiovascular events.
Dayspring, Thomas D +2 more
core +1 more source
Regulation of macrophage apoE secretion and sterol efflux by the LDL receptor
Journal of Lipid Research, 2007 Factors that regulate apolipoprotein E (apoE) secretion by macrophages will have important effects on vessel wall lipid flux and atherosclerosis. Macrophages express the LDL receptor, which binds apoE with high affinity and could thereby affect the net ...
Danijela Lucic +5 more
doaj +1 more source
LDL Receptors in Keratinocytes
Journal of Investigative Dermatology, 1992 The presence of sufficient amounts of cholesterol in the epidermis is necessary for proper functioning of plasma membranes in the viable epidermal cell layers and also for the barrier quality of lipid intercellular bilayers of the stratum corneum. Cholesterol can be generated by local epidermal synthesis, or imported from the circulation as low-density
Ponec, Maria +5 more
openaire +2 more sources
Non-sterol regulation of low density lipoprotein receptor gene expression in T cells
Journal of Lipid Research, 1994 Non-sterol regulation of low density lipoprotein (LDL) receptor gene expression was examined in a mitogen-responsive human T cell line. Stimulation of the leukemic T cell line Jurkat with the phorbol ester phorbol 12-myristate 13-acetate (PMA) and the ...
R S Makar, P E Lipsky, J A Cuthbert
doaj +1 more source
Journal of Lipid Research, 1997 Studies with animal models suggest that saturated fatty acids raise low density lipoprotein (LDL)-cholesterol levels by reducing LDL receptor-mediated clearance. To examine this directly in humans, we studied the effects of lowering dietary saturated fat
V A Mustad +6 more
doaj +1 more source