Results 91 to 100 of about 415,916 (299)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
A Comparison of Two Lead User Measures and an Exploration of their Nature
, 2012 application/pdfThis research compares and contrasts two lead user measures－one from the field of innovation management and one from the field of consumer study. The first measure, Leading Edge Status (LES) was first proposed by Morrison (1995)．The second
勝又, 壮太郎
core
The Outbreak of Lead Poisoning in Opium Users: Presentation and Chelation Therapy
Acta Medica Iranica, 2019 Recently, there have been a few reports of an outbreak of lead poisoning due to opium contaminated with lead in Iran. This study aimed to evaluate the clinical features of lead toxicity in opium abusers, and response to oral chelation therapy based on ...
Abbas Aghabiklooei +3 more
doaj
Changes in hygiene standards for lead in the context of indoor shooting range workers exposure
Medycyna PracyA significant increase in the number of indoor shooting ranges for many years in Poland and most European countries is connected with a raising number of people potentially exposed to lead (both employees and users).
Adam Daragó +3 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Fostering social innovation: identifying lead users for participatory design
, 2013 Participatory design fosters the integration of users into the process of generating new products and services. Although a relatively well established technique known to result in useful and usable outcomes, one of its widely recognized limitations is ...
Tracy Ross (1249074) +5 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Improvements In Bearing Life Using New Sealing Technology [PDF]
, 2005 Lecturepg. 103As many as 91 percent of all rolling element bearings fail to achieve their calculated theoretical lifetimes. One of the primary reasons for this failure is contamination of the lubricants.
Rehmann, Chris
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