Results 111 to 120 of about 415,916 (299)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Architecture and Environmental Numbness [PDF]
صفه, 2015 The quality of living environment depends on users’ active response. Users’ unawareness and passive, insensitive and indifferent reaction to their surroundings—collectively called ‘environmental numbness’—adversely affects users’ wellbeing and will ...
Sara Rahmani
doaj
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
This study investigated the influence of ICT use by librarians on library user satisfaction in public universities in Edo State. The research identified the level of library users’ satisfaction, examined the level of ICT use by librarians, and determined
ADEYEYE, Sophia Vivian +1 more
core
Lead Markets: Drivers of the Global Diffusion of Innovations [PDF]
Multinational corporations are often faced with regionally varying market conditions, local environments and demand preferences. This paper presents the lead markets concept of developing global innovation that takes advantage of the lead market ...
Marian Beise
core
How To Avoid Building Problems Into Pumping Systems
, 1994 Tutorialpg. 125A poorly performing pump frequently exhibits both hydraulic and mechanical problems. Excessive noise, vibration, degradation of discharge pressure, repeated bearing failures, and sometimes impeller breakage lead to high maintenance costs ...
Nelson, William E., Dufour, John W.
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Identifying lead users in a living lab environment
, 2013 This paper emphasizes the identification process of lead users within a living lab environment. Lead users are seen as important contributors to the living lab methodology since they express needs before the general market does.
Coorevits, Lynn +2 more
core
Disabled persons as lead users in mobile user interface design [PDF]
, 2005 In order to understand user needs, traditionally only current users of a productare examined. Classical research on problem solving shows, however, that current users are strongly constrained by their real-world experience, an effect called functional ...
Hannukainen, Pia
core
Traversable Ledger for Responsible Data Sharing and Access Control in Health Research
InformationHealthcare institutions and health registries often store patients’ health data. In order to ensure privacy, sensitive medical information is stored separately from the identifying information of the patient.
Sunanda Bose, Dusica Marijan
doaj +1 more source