Results 131 to 140 of about 415,916 (299)
Employee User Innovation Generated from Routine Improvement Activities:
Maketingu JanaruIn recent years, it has become clear that User Innovation occurs within firms, as well as outside the firm. Employees within an organization may be lead users who contribute to commercially attractive innovations, and more efficient approaches to this ...
Ryohei Yonemitsu
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Root Cause Analysis Of Five Costly Centrifugal Pump Failures
, 1990 Lecturepg. 15Machinery failure analysis and troubleshooting are often pursued in a somewhat haphazard, unstructured fashion. This paper presents a novel, proven, and well focused approach which can quickly lead to the root cause identification of ...
Bloch, Heinz P
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Taking advantage of online communities for generating innovative ideas [PDF]
The use of the internet for business purposes and among consumers is spreading at an impressive rate. Companies use it for a lot of different activities like, for example, marketing, online shopping and customer service.
Tietz, Robert, Herstatt, Cornelius
core
Suppliers versus lead users: examining collaboration in mass customisation [PDF]
, 2008 Mass customisation has been hailed as the manufacturing paradigm of the future, and has accordingly received much academic interest. Nevertheless, it is important to gain a better understanding of the ways in which mass customisation performance may be ...
Al-Zu’b, Zu’bi Mohammad
core
Temperature Measurement At Low Flow On Typical ANSI Chemical Process Pumps
, 2000 Lecturepg. 1Chemical process pumps can be required to handle highly temperature sensitive liquids. Improper operation of such a centrifugal pump can lead to potentially dangerous liquid temperatures within the pump casing.
Kludt, Francis H. +2 more
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source