Results 71 to 80 of about 43,033 (298)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Career Development of College Students through Part-Time Work: The Role of Leader-Member Exchange and Taking Charge Behavior [PDF]

This study examines the potential benefit of college students' part-time work on their career development by focusing on leader-member exchange (LMX) and taking charge behavior in the workplace.
Tomoki Sekiguchi
core  

Pengaruh Leader Member Exchange dan Work Family Conflict terhadap Organizational Citizenship Behavior [PDF]

, 2012
This explanatory research aims to know the effect of Leader-Member Exchange (LMX) and Work-Family Conflict (WFC) to predict Organizational Citizenship Behavior (OCB) and to find which one is more effective to predict OCB.
Meilani Sandjaja, Seger Handoyo, NIDN. 0016026602   +1 more
core  

Examination of Leader-Member Exchange and Employee Performance of Nurses

Sağlık ve Hemşirelik Yönetimi Dergisi, 2019
INTRODUCTION: The aim of this study is to examine the perception of nurses regarding leader-member exchange and employee performance and to investigate the impact of the level of leader-member exchange on employee performance.
Özlem Özer
doaj   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Leader-member exchange and subjective well-being: The moderating role of metacognitive cultural intelligence

, 2020
Purpose: This study examines employees' metacognitive cultural intelligence as a moderator in the relationship between leader-member exchange (LMX) and employees' subjective well-being.
Huong Le (1428589), Jiang, Z, Radford, K, Zhou Jiang (176535), Le, H, Katrina Radford (12489256)   +5 more
core   +1 more source

The Mediating Role of Trust in Manager in The Effect of Leader-Member Exchange on Job Satisfaction in Nursing

Sağlık ve Hemşirelik Yönetimi Dergisi
Aim: The aim of the study is to determine the mediating role of trust in manager in the effect of leader-member exchange on job satisfaction of nurses working in a university hospital.
Nazlıhan Efe Sayan, Aysun Türe
doaj   +1 more source

Roles of perceived exchange quality and organisational identification in predicting turnover intention

IIMB Management Review, 2012
This paper explores whether the perceived quality of the leader–member exchange and the general environment of exchange could predict turnover intention.
Manish Kumar, Shailendra Singh
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source