Advanced Science, EarlyView.By integrating single‐nuclei and spatial transcriptomics, this study presents a stereoscopic landscape of maize leaf to Puccinia polysora infection. Epidermal and mesophyll cells initiate primary defenses via RLPs/RLKs and jasmonic acid signaling. Cell‐cell communication analyses further reveal the underlying the dynamics of the underlying immune ...
Qiongqiong Wang +16 more
wiley +1 more source
Learning components for mixed reality mass casualty incident training: a modified Delphi study. [PDF]
BMC Med EducGyllencreutz L, Pusa S, Baxter R.
europepmc +1 more source
Evaluating the Utilities of Foundation Models in Single‐Cell Data Analysis
Advanced Science, EarlyView.This study delivers the first systematic, task‐level evaluation of single‐cell foundation models across eight core analytical tasks. By benchmarking 10 leading models with the scEval framework, it reveals where foundation models truly add value, where task‐specific methods still dominate, and provides concrete, reproducible guidelines to steer the next
Tianyu Liu +4 more
wiley +1 more source
Ensemble of transformers for depression emotion classification. [PDF]
Cogn NeurodynKasap F, İlhan Omurca S, Ekinci E.
europepmc +1 more source
Paving the Way to Elucidate Hg's Role in Tumorigenesis
Advanced Science, EarlyView.Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li +10 more
wiley +1 more source
Pass/Fail Grading and United States Medical Licensing Examination (USMLE) Step 1 Reform: Implications for Clinical-Year Assessment and USMLE Step 2 Clinical Knowledge (CK) Performance. [PDF]
CureusKhorsand Askari M +2 more
europepmc +1 more source
Advanced Science, EarlyView.This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin +12 more
wiley +1 more source
The necessity of multimodal feedback for learning effective pedagogical policies with reinforcement learning. [PDF]
Sci RepChe L, Guo P, Isleem HF, Wang Z.
europepmc +1 more source
De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning
Advanced Science, EarlyView.Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li +23 more
wiley +1 more source
AI expectation violations and learner engagement in EFL contexts: a cognitive-affective recovery model. [PDF]
Front PsycholYu J, Dai X, Qiu B, Guo W, Wang R, Na M.
europepmc +1 more source