Results 51 to 60 of about 60,420 (305)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Basics of Language for Language Learners [PDF]
, 2017 Second edition ; Tools and Strategies for Language Learning -- Sounding Like a Native Speaker -- Thinking Like a Native Speaker -- Acting Like a Native Speaker ; Item not openly available.
Culicover, Peter W. +1 more
openaire +2 more sources
Fostering autonomy in intercultural language learning in the foreign language classroom: A case study of international students learning English at a higher education institution in Ireland [PDF]
, 2012 This study is concerned with the concept of autonomy in intercultural language learning, understood here as the capacity to take responsibility for one’s own language and intercultural development.
Sudhershan, Aleksandra
core
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Language learning motivation : current insights and implications [PDF]
, 2005 The issue of learner motivation has long exercised researchers and practitioners in the field of language education. However, it is only within the past decade or so that we have witnessed productive interaction between the interests of researchers and
Ushioda, Ema
core
Learner Autonomy: Effectiveness and Challenges at Intermediate Level in Punjab, Pakistan
Journal of Communication and Cultural Trends, 2022 The effectiveness of learner autonomy with respect to second language acquisition has been investigated by various researchers all over the world. Still, it is not given adequate attention in Pakistan, where language proficiency is mostly a matter of ...
Muhammad Rizwan Ilyas, Sadia Azam
doaj +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Studies in Self-Access Learning Journal, 2021 Advising in language learning (ALL) can be defined as “the process of helping someone become an effective, aware, and reflective language learner” (Kato & Mynard, 2016, p. 1).
Hülya Şen, Mümin Şen
doaj +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source