Results 61 to 70 of about 11,751,396 (310)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Conscientization, Dialogue and Collaborative Problem Based Learning

open access: yesJournal of Problem Based Learning in Higher Education, 2013
It has been argued that Paulo Freire’s concept of conscientization, where critical awareness and engagement are central to a problem-posing pedagogy, provides the philosophical principles to underpin Problem Based Learning (PBL). By using dialogue groups
Conscientization, Dialogue and Collaborative Problem Based Learning
doaj  

Deep Reinforcement Learning using Cyclical Learning Rates [PDF]

open access: yesarXiv, 2020
Deep Reinforcement Learning (DRL) methods often rely on the meticulous tuning of hyperparameters to successfully resolve problems. One of the most influential parameters in optimization procedures based on stochastic gradient descent (SGD) is the learning rate.
arxiv  

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

Meta-SGD: Learning to Learn Quickly for Few-Shot Learning [PDF]

open access: yesarXiv, 2017
Few-shot learning is challenging for learning algorithms that learn each task in isolation and from scratch. In contrast, meta-learning learns from many related tasks a meta-learner that can learn a new task more accurately and faster with fewer examples, where the choice of meta-learners is crucial.
arxiv  

Positive semidefinite support vector regression metric learning [PDF]

open access: yesarXiv, 2020
Most existing metric learning methods focus on learning a similarity or distance measure relying on similar and dissimilar relations between sample pairs. However, pairs of samples cannot be simply identified as similar or dissimilar in many real-world applications, e.g., multi-label learning, label distribution learning.
arxiv  

What Interactive Web Features are Most Used [PDF]

open access: yes, 2021
The use of interactive features in websites has become common place on the internet. People use these tools to help navigate and understand the content related to that website.
Tyler, Travis
core   +1 more source

To learn and not to learn – that is the question

open access: yesProcedia - Social and Behavioral Sciences, 2011
AbstractProblem StatementForms of examination in a Higher Educational setting. Existing practice often lacks the connection between learning processes that are deeper and reflective to their character. It is also usually focused on the individual and therefore fails to meet collaborative learning practice.
Maria Gustavson, Ellinor Silius-Ahonen
openaire   +2 more sources

Microglial reprogramming: a potential new frontier in enhancing immunotherapy for melanoma brain metastasis

open access: yesMolecular Oncology, EarlyView.
Microglia act as tumor suppressors during brain metastasis colonization but shift to a tumor‐promoting role after melanoma brain metastases form. NF‐κB/RelA signaling emerges as a key driver of this phenotypic shift. Targeting this pathway reprograms microglia into a pro‐inflammatory state, enhancing antitumor immunity and immune checkpoint inhibitor ...
Noam Savion‐Gaiger   +2 more
wiley   +1 more source

5. Serial Team Teaching and the Evolving Scholarship of Learning: Students’ Perspective

open access: yesCollected Essays on Learning and Teaching, 2011
Faculty and students at the University of Toronto were surveyed and interviewed to form a case study of serial team teaching, in which multiple instructors take turns teaching a segment of the same course in sequence.
Melody Neumann   +12 more
doaj   +1 more source

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