Results 41 to 50 of about 139,691 (264)

How different are the differences? A commentary on the paper “Beat-based dancing to music has evolutionary foundations in vocal learning”

BMC Neuroscience
We propose that while examining homologies and convergences in auditory-motor synchronization between humans and non-human animals is informative, examining differences in behaviour and brain mechanisms can help to better define the boundaries of the ...
Virginia B. Penhune
doaj   +1 more source

Plastic surgical training and the Internet: how plastic surgeons learn

British Journal of Plastic Surgery, 1998
We intend to create a Distance Learning Resource for Plastic Surgeons using all the capabilities of the Internet including video Internet. In order to assess the suitability of current plastic surgery teaching methods for adaptation for use on the Internet we were obliged to ask the fundamental question 'how do surgical trainees learn plastic surgery?'
J, Coates, A, Rowsell
openaire   +2 more sources

Perceptual learning and adult cortical plasticity [PDF]

The Journal of Physiology, 2009
The visual cortex retains the capacity for experience‐dependent changes, or plasticity, of cortical function and cortical circuitry, throughout life. These changes constitute the mechanism of perceptual learning in normal visual experience and in recovery of function after CNS damage. Such plasticity can be seen at multiple stages in the visual pathway,
Charles D, Gilbert, Wu, Li, Valentin, Piech   +2 more
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Plasticity, learning and cognition

, 2011
As is becoming increasingly clear, spiders are not entirely instinct driven and inflexible in their behaviour. Here we review evidence for behavioural plasticity, learning and other cognitive processes such as attentional priming and memory. We first examine these attributes in several natural contexts: predation, interactions with conspecifics and ...
Jakob, Elizabeth, Skow, Christa Danielle, Long, Skye M   +2 more
openaire   +2 more sources

Time scales of memory, learning, and plasticity [PDF]

Biological Cybernetics, 2012
After only about 10 days would the storage capacity of our nervous system be reached if we stored every bit of input. The nervous system relies on at least two mechanisms that counteract this capacity limit: compression and forgetting. But the latter mechanism needs to know how long an entity should be stored: some memories are relevant only for the ...
Tetzlaff, Christian, Kolodziejski, Christoph, Markelic, Irene, Woergoetter, Florentin   +3 more
openaire   +3 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Early processing of traumatic material and contextual information in posttraumatic stress disorder and its relation to memory impairments

Scientific Reports
Posttraumatic stress disorder (PTSD) is characterized by exaggerated responses to trauma-relevant cues and impairments in relation to contextual information.
Francesca Zidda, Frauke Steiger-White, Tobias Winkelmann, Michaela Ruttorf, Jamila Andoh, Frauke Nees, Herta Flor   +6 more
doaj   +1 more source

A saturation hypothesis to explain both enhanced and impaired learning with enhanced plasticity

eLife, 2017
Across many studies, animals with enhanced synaptic plasticity exhibit either enhanced or impaired learning, raising a conceptual puzzle: how enhanced plasticity can yield opposite learning outcomes?
TD Barbara Nguyen-Vu, Grace Q Zhao, Subhaneil Lahiri, Rhea R Kimpo, Hanmi Lee, Surya Ganguli, Carla J Shatz, Jennifer L Raymond   +7 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source