Results 41 to 50 of about 4,901,852 (302)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Erfaringer med e-porteføljer og personlige læringsmiljøer
Dansk Universitetspaedagogisk Tidsskrift, 2011 Siden 2007 har undervisere og studerende på Humanistisk Informatiks første semester løbende eksperimenteret med implementering af digitale porteføljer, og hvad der kan betegnes som personlige læringsmiljøer.
Thomas Ryberg, Helle Wentzer
doaj +2 more sources
The Potential of Artificial Intelligence in Higher Education
Revista Virtual Universidad Católica del Norte, 2021 Artificial Intelligence (AI) is seeping into many aspects of our everyday lives, with common internet applications, smartphones and even household appliances.
Helen Crompton, Donggil Song
doaj +1 more source
Creativity and Conflict: How theory and practice shape student identities in design education [PDF]
, 2009 By exploring the role of student identities in shaping attitudes to learning, this study asks how design students draw on experience to work across theory and practice.
New, Christopher, Tynan, Jane
core +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Scientific Reports, 2023 Deep learning, aided by the availability of big data sets, has led to substantial advances across many disciplines. However, many scientific problems of practical interest lack sufficiently large datasets amenable to deep learning. Prediction of antibody
Brajesh K. Rai +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Heliyon, 2022 The lack of relevant and disaggregated data about schools is a challenge for organizations implementing and funders looking to invest in kindergarten through 12th-grade education programs in New York City (NYC), often forcing organizations to make ...
Steven Azeka +2 more
doaj +1 more source
A review of ten years of implementation and research in aligning learning design with learning analytics at the Open University UK [PDF]
, 2017 There is an increased recognition that learning design drives both student learning experience and quality enhancements of teaching and learning. The Open University UK (OU) has been one of few institutions that have explicitly and systematically ...
Holmes, Wayne +3 more
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source