Results 51 to 60 of about 1,571,252 (311)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Shop Class for the Next Millenium: Education through Computer-Enriched Handicrafts

Journal of Interactive Media in Education, 1998
In this paper we use our experiences with the HyperGami program as a springboard for a broader look at the future of computationally-enriched handicrafts.
Mike Eisenberg, Ann Nishioka Eisenberg
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Instilling purpose and value in the implementation of digital badges in higher education

International Journal of Educational Technology in Higher Education, 2019
This qualitative multi-case study examined digital badge programs being used at three higher education institutions, at the course level, the department level, and the university level.
Jill Stefaniak, Kimberly Carey
doaj   +1 more source

PENDAMPINGAN PENYUSUNAN DESAIN PEMBELAJARAN BERORIENTASI PADA AKM DAN PISA UNTUK GURU

Jurnal Pengabdian dan Edukasi Sekolah, 2022
Based on PISA results, Indonesian students' reading scores are ranked 72 out of 77 participating countries. This minimal ability certainly needs to be overcome, one of which is by increasing the competence of teachers in schools.
Churun Lu’lu’il Maknun, Rahma Nasir, Manto Lumban Gaol, Uncok Manigor Jokkas Siahaan, Ni Made Intan Kertiyani   +4 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Designing adaptive learning environments for continuing education: Stakeholders’ perspectives on indicators and interventions

Computers in Human Behavior Reports
Adaptive learning environments (ALE) provide great potential for personalizing and supporting learning processes in continuing education (CE). However, valid frameworks for designing ALE for CE have been missing so far.
Yvonne M. Fromm, Dirk Ifenthaler
doaj   +1 more source

Dynamic Learning Organisations Supporting Knowledge Creation for Competitive and Integrated Product Design [PDF]

, 2009
Organised by: Cranfield UniversityThis paper shows that learning strategies and a structured approach to turn organisations into learning organisms have a major influence on the success of engineering programs in general, and on integrated design ...
Riel, A., Tichkiewitch, S., Messnarz, R., Spork, G.   +3 more
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Learning Technologies in Support of Self-Directed Learning

Journal of Interactive Media in Education, 1998
Self-directed learning is a continuous engagement in acquiring, applying and creating knowledge and skills in the context of an individual learner's unique problems.
Gerhard Fischer, Eric Scharff
doaj   +1 more source