Results 41 to 50 of about 1,751,270 (304)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Stakeholder engagement as a facilitator of organizational learning [PDF]

open access: yes, 2008
This paper examines the relationship between stakeholder engagement and competence building. Following the dual perspective of the firm, which indicated that managers deal with both transactions and competences concurrently, we argue that stakeholder ...
Eweje, Gabriel, Wu, Minyu
core  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

“The Parents Were Brilliant!” Engaging Parents in STEM Learning: Insights from Preservice Teachers’ Field Experience

open access: yesSocial Sciences
This study describes a field-based experience in parent engagement with preservice teachers, children, parents, and teachers in three Irish elementary schools, focused on a STEM education program, Science for Fun.
Sandra Ryan, Eleanor Walsh, Maeve Liston
doaj   +1 more source

How Does Prior Knowledge Influence Learning Engagement? The Mediating Roles of Cognitive Load and Help-Seeking

open access: yesFrontiers in Psychology, 2020
Research on learning engagement and cognitive load theory have proceeded in parallel with little cross-over of ideas. The aim of this research was to test an integrative model that examines how prior knowledge influences learning engagement via cognitive
Anmei Dong   +2 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Navigating the gender dynamics of food and nutrition security in southwestern Uganda

open access: yesAcademia Nutrition and Dietetics
Household food and nutrition security is a critical aspect of human well-being, yet gender dynamics within households significantly influence access to and control over food resources. Women’s roles in the food system are often undervalued and
Prudence Kemigisha
doaj   +1 more source

Relations among Engagement, Self-Efficacy, and Anxiety in Mathematics among Omani Students [PDF]

open access: yes, 2019
Introduction.  Mathematics is one of the most important academic subjects in school. However, it is one of the most difficult subjects, and both students and teachers face difficulties in this subject.
Abu-Hilal, Maher M., Al Abed, Adnan S
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Implementing Guided Inquiry Learning and Measuring Engagement Using an Electronic Health Record System in an Online Setting [PDF]

open access: yes, 2018
In many courses, practical hands-on experience is critical for knowledge construction. In the traditional lab setting, this construction is easy to observe through student engagement.
Maity, Pallavi   +2 more
core  

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