Results 51 to 60 of about 3,048,804 (307)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Reflections on migratory and mobility patterns and labour market security of Ghanaian youth amidst the Covid-19 crisis

open access: yesSocial Sciences and Humanities Open, 2023
This article examines the changing migratory and mobility patterns of Ghanaian youth during the covid-19 pandemic using mixed methods research design. The study reveals that the patterns of migration, mobility and labor market security of the Ghanaian ...
Abdul Latif Anas   +2 more
doaj   +1 more source

EFFECTIVENESS OF WEB BASED E-LEARNING MEDIA ON INFORMATION AND COMMUNICATION TECHNOLOGY SUBJECT FOR IMPROVE ACHIEVEMENT STUDENTS OF GRADE X SMA NEGERI 1 KALASAN [PDF]

open access: yes, 2012
This research purposed to know the comparative effectiveness of the use of web based E-Learning media in Information Technology and Communication subjects to improve learning achievement students of grade X SMA Negeri 1 Kalasan when compared with ...
Mawar, Ramadhani
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Influence of narrative settings on learning success in virtual reality games – a case study with “Bridge of Knowledge VR”

open access: yesFrontiers in Virtual Reality
Gamification has received increasing attention in research and practice. Although narrations as gamification design elements are frequently implemented into gamified systems, specific content- and context-related design elements of narrations are only ...
Katharina Jahn   +3 more
doaj   +1 more source

PENGEMBANGAN DESAIN MEDIA PRESENTASI BERBASIS GOOGLE SLIDES ADD-ON PEAR-DECK PADA MATERI BARISAN DAN DERET SMA [PDF]

open access: yes, 2023
This research to describe the process of creating, feasibility and practicality of Google Slides Add-on Pear-Deck based presentation media on sequence and series SMA material. This research uses the 4-D development research method.
Alvino, Muhammad Alif Farrel
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Teachers Co-Designing and Enacting Elementary Data Science Curriculum through Connected Learning

open access: yesJournal of Statistics and Data Science Education
We detail a research-practice partnership between an elementary school and educational researchers with a common goal of increasing data science literacy among rural elementary students. Drawing on connected learning theory and using the CT-STEM taxonomy
Danielle Herro   +2 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Creating Makerspace in School Libraries in Nigeria: Implications and Challenges

open access: yesBilgi Dünyası, 2019
Libraries of all types are expected to be places where knowledge and skills are acquired. This paper attempts to look at the implications and challenges of creating makerspace in school libraries in Nigeria.
Oyeronke Adebayo   +3 more
doaj   +1 more source

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