Results 71 to 80 of about 858,456 (300)
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Toward a Broader Understanding: A Formal Concept Analysis of the Micropolitics of a School
Acta Paedagogica Vilnensia, 2018 [full article in English] The micropolitics of a school is one of the key factors that determine changes in member interactions in a learning organization and requires a careful study in order to create a favorable school environment.
Aida Kairienė
doaj +1 more source
Approaches to conceptual clustering [PDF]
, 1985 Methods for Conceptual Clustering may be explicated in two lights. Conceptual Clustering methods may be viewed as extensions to techniques of numerical taxonomy, a collection of methods developed by social and natural scientists for creating ...
Fisher, Douglas, Langley, Pat
core +1 more source
Models of incremental concept formation [PDF]
, 1988 Given a set of observations, humans acquire concepts that organize those observations and use them in classifying future experiences. This type of concept formation can occur in the absence of a tutor and it can take place despite irrelevant and ...
Fisher, Douglas +2 more
core +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
A Concept Learning Approach to Multisensory Object Perception
, 2014 This paper presents a computational model of concept learning using Bayesian inference for a grammatically structured hypothesis space, and test the model on multisensory (visual and haptics) recognition of 3D objects. The study is performed on a set of artificially generated 3D objects known as fribbles, which are complex, multipart objects with ...
Nwogu, Ifeoma +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Application of the SP theory of intelligence to the understanding of natural vision and the development of computer vision [PDF]
, 2014 The SP theory of intelligence aims to simplify and integrate concepts in computing and cognition, with information compression as a unifying theme. This article discusses how it may be applied to the understanding of natural vision and the development of
Wolff, J. Gerard
core +2 more sources
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source