Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Estrategias de aprendizaje que utilizan los estudiantes chinos que aprenden español como lengua extranjera [PDF]
marcoELE. Revista de Didáctica Español Lengua Extranjera, 2018 Este trabajo se enmarca en el análisis de estrategias de aprendizaje que utilizan los estudiantes chinos en el aprendizaje de español. El diseño es cuantitativo; para realizar el objetivo del estudio, se adapta el cuestionario Strategy Inventory for ...
Feng, Yao, Iriarte, Fernando
doaj
STUDY ON THE STUDENTS LEARNING STRATEGIES IN \ud LISTENING COMPREHENSION AT ENGLISH DEPARTMENT OF UMM [PDF]
, 2010 As one of the components of language teaching, listening takes a longest part among other \ud language skills. It becomes a starter to learn language. Students cannot be able to interpret \ud message accurately and creatively if their listening is not ...
FITRI ASTUTI, RAHMA
core
CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
Malaysian and Indonesian Learners: They Are Judges of How They Learn English Most Effectively in and Out of Classrooms [PDF]
, 2016 The position of English is that of a Second Language in Malaysia and a Foreign Language in Indonesia. But the objective is the same that is to enable the learners to communicate effectively and efficiently in social and professional situations. Learners'
Kardiansyah, M. Y. (M) +2 more
core
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
A STUDY ON LEARNING STRATEGIES EMPLOYED BY HIGH ACHIEVERS OF ENGLISH DEPARTMENT,UNIVERSITY OF MUHAMMADIYAH MALANGIN LEARNING ENGLISH [PDF]
, 2007 English language becomes a key to enter the globalization because English is used in any international communication and business recently. Accordingly, it is the most important thing that should be mastered by the students especially students of ...
RAHMADHANI, RAYMON
core
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source