Results 91 to 100 of about 1,038,793 (306)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Language learning strategies employed by engineering students learning English at the tertiary level in Thailand [PDF]

open access: yes, 2000
The present investigation is descriptive-interpretative in nature. It has been designed a) to describe types of language learning strategies which Thai engineering students reported employing; b) to investigate patterns of variations in frequency of ...
Intaraprasert, Channarong   +1 more
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Learning strategies, study habits and social networking activity of undergraduate medical students [PDF]

open access: yes, 2016
Objectives: To determine learning strategies, study habits, and online social networking use of undergraduates at an Irish medical school, and their relationship with academic performance.
O'Deasmhunaigh, Conall   +3 more
core   +1 more source

SPOR BİLİMLERİ FAKÜLTESİ ÖĞRENCİLERİNİN GENEL ÖĞRENME STRATEJİLERİNİ KULLANMA DÜZEYLERİNİN BAZI DEĞİŞKENLERE GÖRE İNCELENMESİ

open access: yesSelçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2017
Bu araştırma, Selçuk Üniversitesi Spor Bilimleri Fakültesi öğrencilerinin genel öğrenme stratejilerini kullanma düzeylerinin bazı değişkenlere cinsiyet, bölüm, sınıf, yaş göre farklılaşıp farklılaşmadığını tespit etmek amacıyla yapılmıştır ...
Özgür Gül   +2 more
doaj  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Lifelong learning strategies

open access: yes, 2011
This article describes how the language learning strategies that learners prefer in learning professional language at tertiary level can be used for lifelong education. It is well known that in language learning students use various learning strategies, but not all learners are equally successful in their studies. This research is based on the analysis
Kavaliauskienė, Galina   +2 more
openaire   +2 more sources

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Using metacognitive strategies to raise awareness of stress and intonation

open access: yesColombian Applied Linguistics Journal, 2018
Few studies have analyzed the impact of language awareness and metacognitive strategies for intelligibility in the context of English as an international language.
Diana Carolina Peñuela
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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